ALCAM (activated leukocyte cell adhesion molecule) - Rat Genome Database

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Gene: ALCAM (activated leukocyte cell adhesion molecule) Chlorocebus sabaeus
Analyze
Symbol: ALCAM
Name: activated leukocyte cell adhesion molecule
RGD ID: 18672578
Description: ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN axon guidance (ortholog); motor neuron axon guidance (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); COVID-19 (ortholog); FOUND IN T cell receptor complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CD166 antigen
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12275,261,104 - 75,475,201 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2275,260,970 - 75,321,082 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604191,034,797 - 91,244,770 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ALCAM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12275,261,104 - 75,475,201 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2275,260,970 - 75,321,082 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604191,034,797 - 91,244,770 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ALCAM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383105,366,909 - 105,576,900 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3105,366,909 - 105,576,900 (+)EnsemblGRCh38hg38GRCh38
GRCh373105,085,753 - 105,295,744 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363106,568,403 - 106,778,434 (+)NCBINCBI36Build 36hg18NCBI36
Build 343106,568,879 - 106,776,709NCBI
Celera3103,484,109 - 103,694,111 (+)NCBICelera
Cytogenetic Map3q13.11NCBI
HuRef3102,460,407 - 102,670,632 (+)NCBIHuRef
CHM1_13105,048,389 - 105,258,778 (+)NCBICHM1_1
T2T-CHM13v2.03108,084,937 - 108,294,916 (+)NCBIT2T-CHM13v2.0
Alcam
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391652,069,359 - 52,273,444 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1652,069,359 - 52,274,437 (-)EnsemblGRCm39 Ensembl
GRCm381652,248,996 - 52,453,081 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1652,248,996 - 52,454,074 (-)EnsemblGRCm38mm10GRCm38
MGSCv371652,249,109 - 52,453,110 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361652,170,261 - 52,373,422 (-)NCBIMGSCv36mm8
Celera1652,580,657 - 52,784,804 (-)NCBICelera
Cytogenetic Map16B5NCBI
cM Map1632.88NCBI
Alcam
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81161,804,932 - 62,005,250 (+)NCBIGRCr8
mRatBN7.21148,336,123 - 48,536,296 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1148,336,169 - 48,537,954 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1157,110,123 - 57,309,926 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01149,771,802 - 49,971,585 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01148,895,907 - 49,095,677 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01150,780,735 - 50,985,083 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1150,781,127 - 50,985,083 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01153,964,563 - 54,165,636 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41149,424,243 - 49,630,071 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11149,481,831 - 49,687,660 (+)NCBI
Celera1148,024,575 - 48,218,199 (+)NCBICelera
Cytogenetic Map11q21NCBI
Alcam
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554276,494,124 - 6,545,963 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554276,494,657 - 6,544,668 (+)NCBIChiLan1.0ChiLan1.0
ALCAM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22103,319,297 - 103,529,920 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13103,325,067 - 103,534,696 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03102,468,354 - 102,677,932 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13109,407,296 - 109,616,518 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3109,407,992 - 109,616,518 (+)Ensemblpanpan1.1panPan2
ALCAM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13310,983,363 - 11,195,170 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3310,983,363 - 11,370,085 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3311,088,414 - 11,300,048 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03311,141,772 - 11,353,405 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3311,141,772 - 11,353,405 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13311,011,197 - 11,222,028 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03311,078,031 - 11,289,490 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03311,486,320 - 11,697,980 (+)NCBIUU_Cfam_GSD_1.0
Alcam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602145,582,988 - 145,771,697 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936701895,376 - 1,084,172 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936701895,414 - 1,084,155 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALCAM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13153,794,993 - 153,998,208 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113153,794,991 - 153,998,241 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213162,988,454 - 163,045,771 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Alcam
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473144,091,769 - 44,280,621 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473144,092,505 - 44,280,022 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 20 60
Low 16 20
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000004331   ⟹   ENSCSAP00000002586
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2275,260,970 - 75,321,082 (-)Ensembl
RefSeq Acc Id: XM_038003247   ⟹   XP_037859175
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604191,034,797 - 91,244,770 (+)NCBI
RefSeq Acc Id: XM_038003248   ⟹   XP_037859176
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604191,034,797 - 91,244,770 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037859175 (Get FASTA)   NCBI Sequence Viewer  
  XP_037859176 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000002586.1
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000002586   ⟸   ENSCSAT00000004331
RefSeq Acc Id: XP_037859175   ⟸   XM_038003247
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R1U7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037859176   ⟸   XM_038003248
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R1U7 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000006293 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000004331.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
NCBI Gene ALCAM ENTREZGENE
PANTHER CELL SURFACE GLYCOPROTEIN MUC18-RELATED UniProtKB/TrEMBL
  PTHR11973:SF2 UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A0D9R1U7 ENTREZGENE, UniProtKB/TrEMBL