ZFP42 (ZFP42 zinc finger protein)

Gene: ZFP42 (ZFP42 zinc finger protein) Chlorocebus sabaeus

Analyze

Symbol:

ZFP42

Name:

ZFP42 zinc finger protein

RGD ID:

18668846

Description:

ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); genomic imprinting (ortholog); in utero embryonic development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); factor XI deficiency (ortholog); genetic disease (ortholog); FOUND IN protein-containing complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

zinc finger protein 42 homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	133,858,632 - 133,866,138 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	133,864,858 - 133,865,790 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	114,278,733 - 114,286,347 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

factor XI deficiency (ISO)

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to leukemia inhibitory factor (ISO)

female gonad development (IEA)

genomic imprinting (ISO)

in utero embryonic development (ISO)

male gonad development (IEA)

positive regulation of transcription by RNA polymerase II (ISO)

spermatid development (ISO)

Cellular Component

cytoplasm (IEA)

nucleus (IEA)

PcG protein complex (IEA)

protein-containing complex (ISO)

transcription regulator complex (IEA)

Molecular Function

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IEA)

metal ion binding (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

ZFP42
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	133,858,632 - 133,866,138 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	133,864,858 - 133,865,790 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	114,278,733 - 114,286,347 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

ZFP42
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	187,995,771 - 188,005,246 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	187,995,771 - 188,005,046 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	188,916,925 - 188,926,200 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	189,153,919 - 189,163,193 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	4	186,226,500 - 186,235,743 (+)	NCBI		Celera
Cytogenetic Map	4	q35.2	NCBI
HuRef	4	184,653,751 - 184,663,028 (+)	NCBI		HuRef
CHM1_1	4	188,893,484 - 188,902,761 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	191,341,992 - 191,352,990 (+)	NCBI		T2T-CHM13v2.0

Zfp42
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	43,748,100 - 43,760,041 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	43,748,100 - 43,760,017 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	43,295,067 - 43,307,009 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	43,295,063 - 43,306,980 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	44,380,421 - 44,392,363 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	44,793,888 - 44,805,777 (-)	NCBI		MGSCv36	mm8
Celera	8	45,980,115 - 45,992,188 (-)	NCBI		Celera
Cytogenetic Map	8	A4	NCBI
cM Map	8	23.89	NCBI

Zfp42
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	55,568,903 - 55,577,883 (+)	NCBI		GRCr8
mRatBN7.2	16	48,836,463 - 48,845,443 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	48,836,648 - 48,845,401 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	54,232,714 - 54,241,617 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	57,606,749 - 57,615,729 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	52,870,722 - 52,879,624 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	52,016,590 - 52,026,346 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	16	51,743,302 - 51,753,068 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	52,150,048 - 52,158,306 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	52,150,122 - 52,158,381 (+)	NCBI
Celera	16	46,809,653 - 46,819,299 (+)	NCBI		Celera
Cytogenetic Map	16	q12.1	NCBI

Zfp42
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	21,222,138 - 21,227,341 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	21,222,129 - 21,227,341 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZFP42
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	185,718,834 - 185,735,904 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	186,073,425 - 186,090,495 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	180,152,673 - 180,162,899 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	192,342,123 - 192,350,455 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	192,349,144 - 192,350,076 (+)	Ensembl	panpan1.1		panPan2

ZFP42
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	43,091,607 - 43,092,521 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	43,091,607 - 43,092,371 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	43,582,074 - 43,582,988 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	45,313,708 - 45,314,622 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	45,313,708 - 45,314,472 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	43,273,694 - 43,274,608 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	43,880,184 - 43,881,098 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	43,983,748 - 43,984,662 (-)	NCBI		UU_Cfam_GSD_1.0

Zfp42
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	36,322,857 - 36,323,627 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936554	1,786,355 - 1,787,125 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZFP42
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	7,402,071 - 7,403,247 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	7,401,729 - 7,409,027 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	8,282,671 - 8,290,195 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Zfp42
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624769	18,934,076 - 18,935,002 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624769	18,933,990 - 18,935,008 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium
Low	14	9	14
Below cutoff	6	8	11

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008000510	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000018443 ⟹ ENSCSAP00000017899

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	7	133,864,858 - 133,865,790 (+)	Ensembl

RefSeq Acc Id:

XM_008000510 ⟹ XP_007998701

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	7	133,858,632 - 133,866,138 (+)	NCBI
Vero_WHO_p1.0	NW_023666037	114,278,733 - 114,286,347 (+)	NCBI

Sequence:

show sequence

CCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGTCCGGCCTAAAAGCGT
AAATGTGATTACACCTACGCGTATTTGTTCAACAGACATTTATTGAGTGTTCACCACGTGCTAA
TGCGGGGTGTCTGGGCTCGGGAGGCGCTGCCACGTGGCGGATGCGCAGTGCCCGGCGGCCGGGC
TGAGGGGTGAACGCGGGGACCAGGGGGCCCCGGGCTGAGGGTTTGCGTGCGGGCCGGGTGCCTG
GGGGCCCCAGGCTGAGAGTGCGCGCGCCGCCCCGGTGCCAGGCGGCTCCCGGCAGAAGGTGAGC
GCGCGGGCCAGGGGGCTCCAGGGCGGCGCCCCAGGGCGGGGCGGGCCACGCCCTCCCTAACCCT
GGCGGAGCTGAAGGGTTGGCGTAGCCTGATTAGACCGCGTCAGTCCGGAGGGTGGGCCTTGGGA
GGGGGCGCAGGGCAGTCCACGTTTGCACTGCAGTTTCTCCTTTGTTTTACGTTTGGAAGGAGGT
GGCATTGAAAATAGCAGAGCGCTTCGCAGTAACAGGGACAAATGGACTGAGGCTGGAGCCTGTG
TGAACAGAACAGAAGAGGCGTTCGCTGTCGTAGAGCTCACAGTCTAGCAGGTGTTTGCTGGAGA
CAATTTACTCAGATCACTACTCCCTGGAGGTGGTTGATACATCCTGGTGTAAACCTTCAAGAAG
GACACAGGCAGGAAAACATGAACCAGCAAGTGAAGAAACGGGCAAAGACGAGACGCCAGAAAGA
CCTGGGTGGAAGAGCCCCCCAGAGGGCTAAGCCCAGGCCAGGCAAGGCAAGCCAAGACCTGCAG
GCGGAAATGGAGCCTGTGGGCACAGTGTGGGCCTTCTGTGATGACCATGTGTGCTATGAGCCTG
GCCCTCAGGCTGCTGGAGAGGACGATTTCTCAGACTGTTACATAGAATGCATCATAAGGGGTGA
GTTTTCTCAACCCATCCTGGAAGAGGACTCACTTTTTGAGTCCTTGGAATACCTAAAGAAAGGA
TCCGAACAAGAGCTTTCTCAAAAGGTTCTCGAAGCAAGCTCCCTTCTTGAATGTTCTTTGCAAT
ACATGAAAAAAGGGGCAAAGAAAGAGCTTCCTCAAAAGATCGTTGGAGAGAATTCACTCGAGTA
TTCTGAGCACGTGACAGGCAAGAAGCTTCCGCCTGGAGGAATACCTGGCAATGACCTATCAGAT
CCTAAACAGCTCGCAGAATTTGCTAGAAAGAAGCCCCCCATAAATAAAGAATATGACAGTCTGA
GTGCAATCGCTTGTCCTCAGAGTGGATGCAGTAAGAAGTTGAGGAACAGAGCTGCCCTGAAAAA
GCATCTCCTCACTCATGGTCCCCGAGACCACATCTGTGCAGAATGCGGGAAAGCCTTCGTTGAG
AGCTCAAAACTAAAAAGACATTTCCTGGTTCACACTGGAGAGAAACCGTTTCAGTGCACTTTTG
AAGGGTGCGGAAAGCGCTTCTCCCTGGACTTCAATTTGCGTACACATGTACGCATCCACACGGG
GGAGAAACGTTTCGTGTGTCCCTTTGAAGGCTGTAACAGGAGGTTTACTCAGTCAAATAACCTG
AAATCCCACATCCTAACGCATGCAAATACGAACAAGAATGAACAAGACGGAGAGTGGTCCTCCA
ACAGGATACGCAGAAGAGTGATCAGTGATCAGTGACAAATCGGCCTCTTGATTATTGTTTCTAG
GATGGAATTTTTAAATCAATATTGCAGCCCCAAAAGTGGTTATAATTTGGTGTTTCTAAGATGC
TCCTACACTTTGTGATACCGTTTTGAGAACATGGTGTATTTTTTTTCTTTTTTGTTTTATTTAG
AACTTTGTATTCTTAAAATGTGCTTCCAACAGGAAGGTCAGTGATAAACTGACTTCAAAAGCAA
GACCTTTAATATATTATCTGTTGGATTATTAGATATAAGACTTATTTTCATGTACTATAAATAT
GAAAATAACTTTGATTTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_007998701	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000017899.1

RefSeq Acc Id:	XP_007998701 ⟸ XM_008000510
- UniProtKB:	A0A0D9SAL0 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000017899 ⟸ ENSCSAT00000018443

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000000092	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000018443.1	UniProtKB/TrEMBL
Gene3D-CATH	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	Znf_C2H2_sf	UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/TrEMBL
NCBI Gene	ZFP42	ENTREZGENE
PANTHER	TRANSCRIPTIONAL REPRESSOR PROTEIN YY	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN 42 HOMOLOG	UniProtKB/TrEMBL
Pfam	zf-C2H2	UniProtKB/TrEMBL
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
SMART	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57667	UniProtKB/TrEMBL
UniProt	A0A0D9SAL0	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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