SHPK (sedoheptulokinase) - Rat Genome Database

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Gene: SHPK (sedoheptulokinase) Chlorocebus sabaeus
Analyze
Symbol: SHPK
Name: sedoheptulokinase
RGD ID: 18668276
Description: ENCODES a protein that exhibits kinase activity (inferred); sedoheptulokinase activity (inferred); INVOLVED IN cellular response to interleukin-13 (ortholog); cellular response to interleukin-4 (ortholog); pentose-phosphate shunt, non-oxidative branch (ortholog); ASSOCIATED WITH Abderhalden-Kaufmann-Lignac Syndrome (ortholog); Canavan disease (ortholog); cystinosis (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,104,139 - 3,138,545 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl163,105,527 - 3,138,389 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605918,691,695 - 18,720,574 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SHPK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,104,139 - 3,138,545 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl163,105,527 - 3,138,389 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605918,691,695 - 18,720,574 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SHPK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38173,608,240 - 3,636,250 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl173,608,240 - 3,636,250 (-)EnsemblGRCh38hg38GRCh38
GRCh37173,511,534 - 3,539,544 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36173,458,305 - 3,486,365 (-)NCBINCBI36Build 36hg18NCBI36
Build 34173,458,304 - 3,486,365NCBI
Celera173,525,274 - 3,553,357 (-)NCBICelera
Cytogenetic Map17p13.2NCBI
HuRef173,403,309 - 3,431,324 (-)NCBIHuRef
CHM1_1173,522,339 - 3,550,373 (-)NCBICHM1_1
T2T-CHM13v2.0173,497,275 - 3,525,315 (-)NCBIT2T-CHM13v2.0
Shpk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391173,090,153 - 73,115,337 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1173,090,286 - 73,115,337 (+)EnsemblGRCm39 Ensembl
GRCm381173,199,132 - 73,224,511 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1173,199,460 - 73,224,511 (+)EnsemblGRCm38mm10GRCm38
MGSCv371173,012,984 - 73,038,008 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,015,677 - 73,040,701 (+)NCBIMGSCv36mm8
Celera1180,736,568 - 80,761,767 (+)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1145.25NCBI
Shpk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81058,316,065 - 58,340,489 (+)NCBIGRCr8
mRatBN7.21057,817,551 - 57,841,981 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1057,817,629 - 57,841,980 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1062,473,323 - 62,497,644 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01061,961,788 - 61,986,111 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01057,460,929 - 57,485,241 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01059,765,328 - 59,789,676 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1059,765,258 - 59,789,678 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01059,504,502 - 59,528,849 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41060,075,861 - 60,100,209 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11060,089,463 - 60,112,512 (+)NCBI
Celera1056,940,488 - 56,964,835 (+)NCBICelera
Cytogenetic Map10q24NCBI
Shpk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546713,169,063 - 13,212,269 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546713,169,072 - 13,209,585 (+)NCBIChiLan1.0ChiLan1.0
SHPK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21911,219,432 - 11,248,307 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11713,186,609 - 13,235,292 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0173,657,764 - 3,686,791 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1173,654,237 - 3,683,422 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl173,654,237 - 3,683,421 (-)Ensemblpanpan1.1panPan2
SHPK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1947,445,969 - 47,486,756 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha946,608,830 - 46,649,250 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0948,291,864 - 48,332,347 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl948,288,115 - 48,320,151 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1947,069,503 - 47,110,121 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0947,358,836 - 47,399,242 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0947,414,415 - 47,454,872 (-)NCBIUU_Cfam_GSD_1.0
Shpk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560255,558,019 - 55,586,647 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936677314,294 - 342,855 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936677314,328 - 342,892 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHPK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1249,712,177 - 49,732,246 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11249,713,224 - 49,732,319 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21251,572,902 - 51,592,034 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Shpk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247866,267,914 - 6,297,626 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247866,271,636 - 6,296,872 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 4 4
Low 32 20 56
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008009873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000011684   ⟹   ENSCSAP00000009750
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl163,105,527 - 3,138,389 (-)Ensembl
RefSeq Acc Id: XM_008009873   ⟹   XP_008008064
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1163,104,139 - 3,138,545 (-)NCBI
Vero_WHO_p1.0NW_02366605918,691,695 - 18,720,574 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008008064 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000009750.1
Reference Protein Sequences
RefSeq Acc Id: XP_008008064   ⟸   XM_008009873
- UniProtKB: A0A0D9RMB1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000009750   ⟸   ENSCSAT00000011684


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013604 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011684.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.40 UniProtKB/TrEMBL
InterPro ATPase_NBD UniProtKB/TrEMBL
  Carb_kinase_FGGY_N UniProtKB/TrEMBL
  SHK UniProtKB/TrEMBL
NCBI Gene SHPK ENTREZGENE
PANTHER SEDOHEPTULOKINASE UniProtKB/TrEMBL
  SUGAR KINASE UniProtKB/TrEMBL
Pfam FGGY_N UniProtKB/TrEMBL
Superfamily-SCOP SSF53067 UniProtKB/TrEMBL
UniProt A0A0D9RMB1 ENTREZGENE, UniProtKB/TrEMBL