MYPN (myopalladin) - Rat Genome Database

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Gene: MYPN (myopalladin) Chlorocebus sabaeus
Analyze
Symbol: MYPN
Name: myopalladin
RGD ID: 18663831
Description: ENCODES a protein that exhibits cytoskeletal protein binding (inferred); muscle alpha-actinin binding (inferred); protein kinase activity (inferred); INVOLVED IN sarcomere organization (inferred); ASSOCIATED WITH arrhythmogenic right ventricular cardiomyopathy (ortholog); atrial fibrillation (ortholog); Autosomal Dominant Intellectual Developmental Disorder 70 (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1963,173,243 - 63,279,777 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl963,174,804 - 63,279,133 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604823,941,972 - 24,047,621 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MYPN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1963,173,243 - 63,279,777 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl963,174,804 - 63,279,133 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604823,941,972 - 24,047,621 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
MYPN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381068,087,897 - 68,212,017 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1068,087,897 - 68,212,017 (+)EnsemblGRCh38hg38GRCh38
GRCh371069,865,764 - 69,971,774 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361069,539,256 - 69,641,780 (+)NCBINCBI36Build 36hg18NCBI36
Build 341069,538,999 - 69,641,464NCBI
Celera1063,143,861 - 63,246,302 (+)NCBICelera
Cytogenetic Map10q21.3NCBI
HuRef1063,865,720 - 63,971,479 (+)NCBIHuRef
CHM1_11070,147,622 - 70,253,538 (+)NCBICHM1_1
T2T-CHM13v2.01068,956,458 - 69,080,820 (+)NCBIT2T-CHM13v2.0
Mypn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391062,951,574 - 63,039,731 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1062,951,574 - 63,039,731 (-)EnsemblGRCm39 Ensembl
GRCm381063,115,795 - 63,203,952 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1063,115,795 - 63,203,952 (-)EnsemblGRCm38mm10GRCm38
MGSCv371062,578,543 - 62,666,700 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361062,511,137 - 62,604,287 (-)NCBIMGSCv36mm8
Celera1064,215,962 - 64,304,031 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.54NCBI
Mypn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82025,435,554 - 25,521,149 (+)NCBIGRCr8
mRatBN7.22025,429,898 - 25,522,443 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2025,436,843 - 25,522,443 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2026,129,740 - 26,215,377 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02025,482,765 - 25,568,401 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02026,069,325 - 26,154,935 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02026,988,820 - 27,074,106 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2026,988,774 - 27,074,138 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02028,829,554 - 28,914,644 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42025,457,133 - 25,531,818 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12025,471,952 - 25,589,885 (-)NCBI
Celera2026,744,077 - 26,818,492 (+)NCBICelera
Cytogenetic Map20p11NCBI
Mypn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542520,471,047 - 20,544,105 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542520,461,654 - 20,545,626 (+)NCBIChiLan1.0ChiLan1.0
MYPN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2880,270,078 - 80,375,293 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11080,275,401 - 80,380,616 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01064,590,232 - 64,696,512 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11066,916,666 - 67,006,529 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1066,902,008 - 67,004,967 (+)Ensemblpanpan1.1panPan2
MYPN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1419,364,146 - 19,468,827 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl419,381,416 - 19,465,995 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha419,496,464 - 19,606,631 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0419,633,801 - 19,743,812 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl419,651,134 - 19,737,009 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1419,516,593 - 19,626,556 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0419,738,577 - 19,848,657 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0420,081,868 - 20,191,947 (+)NCBIUU_Cfam_GSD_1.0
Mypn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721361,561,178 - 61,649,670 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493652110,050,638 - 10,142,395 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493652110,050,638 - 10,142,395 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYPN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1471,299,505 - 71,387,025 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11471,283,271 - 71,388,591 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21477,293,135 - 77,398,516 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Mypn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247542,467,071 - 2,598,386 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247542,466,980 - 2,596,288 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 13
Below cutoff 16 4 36

Sequence


RefSeq Acc Id: ENSCSAT00000005574   ⟹   ENSCSAP00000003793
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl963,174,804 - 63,279,133 (-)Ensembl
RefSeq Acc Id: XM_007963283   ⟹   XP_007961474
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1963,173,243 - 63,276,155 (-)NCBI
Vero_WHO_p1.0NW_02366604823,941,972 - 24,044,182 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007963285   ⟹   XP_007961476
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1963,173,561 - 63,263,783 (-)NCBI
Vero_WHO_p1.0NW_02366604823,941,972 - 24,031,884 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038009168   ⟹   XP_037865096
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604823,941,972 - 24,047,621 (-)NCBI
RefSeq Acc Id: XM_038009169   ⟹   XP_037865097
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604823,941,972 - 24,047,621 (-)NCBI
RefSeq Acc Id: XM_038009170   ⟹   XP_037865098
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604823,941,972 - 24,016,920 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007961474 (Get FASTA)   NCBI Sequence Viewer  
  XP_007961476 (Get FASTA)   NCBI Sequence Viewer  
  XP_037865096 (Get FASTA)   NCBI Sequence Viewer  
  XP_037865097 (Get FASTA)   NCBI Sequence Viewer  
  XP_037865098 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000003793.1
RefSeq Acc Id: XP_007961474   ⟸   XM_007963283
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R5A4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007961476   ⟸   XM_007963285
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R5A4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000003793   ⟸   ENSCSAT00000005574
RefSeq Acc Id: XP_037865096   ⟸   XM_038009168
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R5A4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037865097   ⟸   XM_038009169
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037865098   ⟸   XM_038009170
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000007529 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000005574.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
KEGG Report csab:103216100 UniProtKB/TrEMBL
NCBI Gene MYPN ENTREZGENE
PANTHER IG-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  IMMUNOGLOBULIN UniProtKB/TrEMBL
Pfam I-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A0D9R5A4 ENTREZGENE, UniProtKB/TrEMBL