LLPH (LLP homolog, long-term synaptic facilitation factor)

Gene: LLPH (LLP homolog, long-term synaptic facilitation factor) Chlorocebus sabaeus

Analyze

Symbol:

LLPH

Name:

LLP homolog, long-term synaptic facilitation factor

RGD ID:

18660734

Description:

ENCODES a protein that exhibits basal RNA polymerase II transcription machinery binding (inferred); RNA binding (inferred); INVOLVED IN positive regulation of dendritic spine development (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN chromosome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

protein LLP homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	61,806,190 - 61,813,789 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	61,805,855 - 61,813,742 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	183,910,252 - 183,918,710 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

dendrite extension (IEA)

positive regulation of dendritic spine development (ISO)

Cellular Component

chromosome (ISO)

nucleolus (IEA)

Molecular Function

basal RNA polymerase II transcription machinery binding (IEA)

protein binding (ISO)

RNA binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

LLPH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	61,806,190 - 61,813,789 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	61,805,855 - 61,813,742 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	183,910,252 - 183,918,710 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LLPH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	66,116,555 - 66,130,750 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	66,116,555 - 66,130,750 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	66,510,335 - 66,524,530 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	64,803,109 - 64,810,800 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	12	66,183,159 - 66,190,843 (-)	NCBI		Celera
Cytogenetic Map	12	q14.3	NCBI
HuRef	12	63,569,736 - 63,577,414 (-)	NCBI		HuRef
CHM1_1	12	66,483,713 - 66,491,397 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	66,096,061 - 66,110,256 (-)	NCBI		T2T-CHM13v2.0

Llph
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	120,062,967 - 120,067,976 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	120,062,975 - 120,068,487 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	120,227,048 - 120,232,071 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	120,227,070 - 120,232,582 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	119,664,116 - 119,669,126 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	119,630,120 - 119,635,130 (+)	NCBI		MGSCv36	mm8
Celera	10	122,589,231 - 122,594,255 (+)	NCBI		Celera
Cytogenetic Map	10	D2	NCBI
cM Map	10	67.94	NCBI

Llph
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	57,620,925 - 57,625,924 (+)	NCBI		GRCr8
mRatBN7.2	7	55,735,317 - 55,740,341 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	55,735,400 - 55,740,339 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	57,643,034 - 57,646,763 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	59,846,217 - 59,849,946 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	59,623,559 - 59,627,289 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	65,004,544 - 65,009,509 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	65,005,791 - 65,008,823 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	65,223,409 - 65,228,370 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	126,240,444 - 126,241,523 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	59,510,526 - 59,515,726 (+)	NCBI
Celera	7	52,492,001 - 52,495,730 (+)	NCBI		Celera
Cytogenetic Map	7	q22	NCBI

Llph
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955458	12,785,194 - 12,791,915 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955458	12,785,194 - 12,791,918 (-)	NCBI	ChiLan1.0	ChiLan1.0

LLPH
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	28,222,470 - 28,229,670 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	28,219,238 - 28,226,435 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	22,777,107 - 22,784,862 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	23,283,068 - 23,290,777 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	23,283,068 - 23,290,777 (+)	Ensembl	panpan1.1		panPan2

LLPH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	8,631,891 - 8,638,922 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	8,631,879 - 8,639,226 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	8,562,755 - 8,570,274 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	8,743,792 - 8,751,304 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	8,742,707 - 8,751,589 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	8,620,085 - 8,627,597 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	8,866,273 - 8,873,322 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	8,987,767 - 8,994,826 (-)	NCBI		UU_Cfam_GSD_1.0

Llph
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	49,907,501 - 49,912,796 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936545	4,195,768 - 4,202,613 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936545	4,197,328 - 4,202,557 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LLPH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	30,474,375 - 30,485,057 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	30,478,545 - 30,485,534 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	33,720,154 - 33,726,378 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Llph
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624802	2,176,739 - 2,182,680 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	36		35
Low		20	25
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008003925	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000002421 ⟹ ENSCSAP00000000735

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	11	61,805,855 - 61,813,742 (-)	Ensembl

RefSeq Acc Id:

XM_008003925 ⟹ XP_008002116

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	11	61,806,190 - 61,813,789 (-)	NCBI
Vero_WHO_p1.0	NW_023666037	183,910,252 - 183,918,710 (+)	NCBI

Sequence:

show sequence

CTCCCGGCATGCACTGCGTCCGGCCCGGGTGTCCTCTGCCCGGAAGACGGAAGTGCAAAGACTT
CCGGTCGGCGTGATCCTGAGGCGTGTGTGTTGGTTTTTCAGGTAAAACATGGCTAAAAGCTTAC
GGAGTAAGTGGAAAAGAAAGATGCGTGCTGAAAAGAGAAAAAAGAATGCCCCAAAGGAGCTCAG
CAGGCTTAAAAGTATTCTCAAACTAGAAGGTGATGTTTTAATGAAAGATGTTCAAGAGATAGCA
ACTGTGGTGGTACCCAAACGCAAACATTGCCAAGAGAAAATGCAATGTGAGGTAAAAGATGAAA
AAGATGACATGAAAATGGAGACTGATATTAAGAGAAACAAAAAGACTCTTCTAGACCAGCATGG
ACAGTACCCAATATGGATGAACCAAAGGCAAAGAAAAAGGCTGAAGGCAAAGCGAGAGAAAGGA
AAGGGGAAAAGCAAAGCAAAAGCAGTGAAAGTGGCAAAGGGTTTGGCCTGGTAGACTCTTAAAA
CCTTGGAAAATGCCACACGGGATAGATGATGGATTAGAATGTATACACATGTATACTTTGATTT
CAGCTGCCACCAAATGAAAACTATTTGTTTTCCTATTTTAACTTGGCCTTTTTTCTGCAGTTCA
AACCCAGCATAACTCCTCAAGTTTGTTTTGGGAACTTAAATAAAATATTTTCTTTGATACAAAC
AAGCTCTACTGATACTTTAATTGGATGCTACCCAATATCCAGTTATAATCAGGCCTCAAAGTTC
TGTCAGGTATTAATGTGGTTAGACGTTCTTACAAGTGGTAATTATAGTCAGTAGAGATAAAACA
GATGATGTACTGACAAATTTTTGTGAACTCAGATTTAAAGAAAGCTGTTGTATAATCATATCGT
TTAAAAATACAACATTAGGGCCCGGGCACGGTGGCTCACACCTGTAATCCCAGCACTTCGGGAG
GCCGAGGCAGGTGGATCACCAGGTCATTTCAAGACCAGCCTGGCTAATATGGTGAAACCCCATC
TCTACTAAAAATACGAAATCAGTTGAGCATGGTGGCGCGCACCTGTAGTCCCAGCTACTCAGGA
GGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGAGGTTGCAATGAGCCGAGATTGCCCCA
CTGCACTCCACCCTGGGCAACGGAGCAGGACTCTGTCTCAAAAAAAAAAAAAAAAATACATTAA
TGGATCTTATAAAGTACTTGTGTGGAGCTTTGATTCCACAGAATAAAAGATATTTTGTGTGTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008002116	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000000735
	ENSCSAP00000000735.1

RefSeq Acc Id:	XP_008002116 ⟸ XM_008003925
- UniProtKB:	A0A0D9QWJ6 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000000735 ⟸ ENSCSAT00000002421

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000004392	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000002421.1	UniProtKB/TrEMBL
InterPro	LAPS18-like	UniProtKB/TrEMBL
KEGG Report	csab:103238658	UniProtKB/TrEMBL
NCBI Gene	LLPH	ENTREZGENE
PANTHER	PROTEIN LLP HOMOLOG	UniProtKB/TrEMBL
	PTHR34253	UniProtKB/TrEMBL
Pfam	Laps	UniProtKB/TrEMBL
UniProt	A0A0D9QWJ6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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