ACOT6 (acyl-CoA thioesterase 6) - Rat Genome Database

Name: ACOT6
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: ACOT6 (acyl-CoA thioesterase 6) Chlorocebus sabaeus

Analyze

Symbol:

ACOT6

Name:

acyl-CoA thioesterase 6

RGD ID:

18642323

Description:

ENCODES a protein that exhibits fatty acyl-CoA hydrolase activity (inferred); INVOLVED IN acyl-CoA metabolic process (inferred); fatty acid metabolic process (inferred); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); schizophrenia (ortholog); FOUND IN cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

putative acyl-coenzyme A thioesterase 6

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ACOT6 (acyl-CoA thioesterase 6)	NCBI	Ortholog
Mus musculus (house mouse):	Acot6 (acyl-CoA thioesterase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Acot6 (acyl-CoA thioesterase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ACOT6 (acyl-CoA thioesterase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ACOT6 (acyl-CoA thioesterase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Acot6 (acyl-CoA thioesterase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ACOT6 (acyl-CoA thioesterase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Acot6 (acyl-CoA thioesterase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	50,826,561 - 50,834,462 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666053	39,008,311 - 39,016,103 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

intellectual disability (ISO)

schizophrenia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acyl-CoA metabolic process (IEA)

fatty acid metabolic process (IEA)

Cellular Component

cytosol (ISO)

Molecular Function

fatty acyl-CoA hydrolase activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ACOT6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	50,826,561 - 50,834,462 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666053	39,008,311 - 39,016,103 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

ACOT6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	73,610,945 - 73,619,888 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	73,610,945 - 73,619,888 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	74,077,649 - 74,086,592 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	73,153,301 - 73,156,345 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	14	54,119,631 - 54,122,671 (+)	NCBI		Celera
Cytogenetic Map	14	q24.3	NCBI
HuRef	14	54,251,313 - 54,254,353 (+)	NCBI		HuRef
CHM1_1	14	74,023,109 - 74,026,149 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	67,818,457 - 67,827,400 (+)	NCBI		T2T-CHM13v2.0

Acot6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	84,147,538 - 84,158,128 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	84,147,428 - 84,158,123 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	84,100,654 - 84,109,783 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	84,100,654 - 84,111,349 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	85,441,604 - 85,450,733 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	84,990,402 - 85,001,102 (+)	NCBI		MGSCv36	mm8
Celera	12	85,547,614 - 85,556,743 (+)	NCBI		Celera
Cytogenetic Map	12	D1	NCBI
cM Map	12	39.04	NCBI

Acot6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	109,463,513 - 109,472,587 (+)	NCBI		GRCr8
mRatBN7.2	6	103,732,372 - 103,741,446 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	103,732,372 - 103,741,446 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	103,894,180 - 103,903,254 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	104,193,399 - 104,202,473 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	103,562,847 - 103,571,921 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	107,581,357 - 107,590,431 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	107,581,608 - 107,590,373 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	117,946,002 - 117,963,918 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	108,146,690 - 108,155,388 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	108,150,145 - 108,193,873 (+)	NCBI
Celera	6	101,561,356 - 101,570,442 (+)	NCBI		Celera
Cytogenetic Map	6	q31	NCBI

ACOT6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	74,691,158 - 74,709,999 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	73,907,658 - 73,926,511 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	54,171,652 - 54,179,322 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	73,029,435 - 73,037,223 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	73,034,520 - 73,037,170 (+)	Ensembl	panpan1.1		panPan2

ACOT6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	46,905,354 - 46,911,627 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	46,852,880 - 46,911,640 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	46,589,770 - 46,595,919 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	47,134,480 - 47,140,629 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	47,081,692 - 47,140,579 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	46,802,068 - 46,808,222 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	46,820,344 - 46,826,490 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	47,210,706 - 47,216,944 (+)	NCBI		UU_Cfam_GSD_1.0

Acot6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	29,130,634 - 29,138,703 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936488	2,930,114 - 2,939,325 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936488	2,930,291 - 2,938,300 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACOT6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	96,984,716 - 96,992,873 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	96,984,547 - 96,990,400 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	102,742,804 - 102,785,288 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Acot6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624734	27,901,129 - 27,908,976 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007987228	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007987229	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_007987228 ⟹ XP_007985419

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	24	50,826,561 - 50,834,462 (+)	NCBI
Vero_WHO_p1.0	NW_023666053	39,008,311 - 39,016,103 (+)	NCBI

Sequence:

show sequence

CCTGAGGTGTGATCCACCCACCTGGGCCTCCCAAAAATTCTAGGATTACAGGCATGAGCCACCG
CGCCCGGCCGGATTGGTCATTAACTCTTATTTCAACAGATACTCCTTCATTTGGGACACTGGTG
TATTTGCACAAATTCTAGGCGCTCCACGCAGCGGCCTGGAGCCTGTCCCCAAGTCCAACCAATG
GGAGTAGTGTTAAGGGTTCCGCCCTCGACTCCTTTCAAGCACCAGGCAAAGCCGCCAGGCCCGC
CCACTGACTCCGGGGAGCTGAGTCGTCCCTGTTCTACCCAAGTCGGGATGGCAGCGACGCTGAT
CCTGGAGCCCGCGGGCCGCTGCTGCTGGGATGAGCCCGTGCGCATCGCCGCGCGCGGCCTGGCC
CCGGAACAGCGGGTCACGCTGCGCACGTCCCTGCACGACGAGAAGGGCGCGCTCTTCCGGGCCC
ACGCGCGCTACCGCGCCGACGCCCGCGGCGAGCTGGACCTGGAGCGCGCGCCCGCGCTGGGCGG
CAGCTTCGCGGGGCTCGAGCCCATGGGGCTGCTCTGGGCGTTGGAGCCCGAGAAAGCCTTGGTG
CGGCTGGTGAAGCGCGACGTGCGGACGCCCTTTGCCGTGGAGCTGGAAGTGCTGGACGGCCACG
GCCCTGAGCCCGGGCGGCTGCTGTGTCGGGCGCAGAACAAGCGCGACTTTCTCCAACCGGGGGT
GCGGCGCGAGCCGGTGCGCGCGGGCCGGGTGCGCGCCGCGCTCTTCCTGCCGCCGGGCGAGGGG
CCCTTTCCTGGGGTCATTGATCTGTTTGGGAGTGGCGGTGGCCTTTGTGAATACAGGGCCAGCC
TCCTGGCCGGACACGGTTTTGCTGTGCTTGCCCTGGCTTATTTCAGATTTGAAGACCTCCCTGA
AGATCTGAATGATGTACATCTGGAGTACTTTGAAGAAGCCGTGGACTTTATGCTGCAGCATCCA
GAGGTGAAAGGTCCTAGTATTGGGCTTCTTGGATTTTCCAAAGGAGGTGACCTGTGTCTCTCAA
TGGCTTCTTTCTTGAAGGGCATCACAGCCACTGTTCTTATCAATGCCTGTGTAGCCAACACCAT
AACTCCTCTACATTACAAGGATATGATTATTCCTAAACTTGTCGATGATCTAGGAAAAGTAAAA
ATCACGAAGTCAGGATTTCTCACTTTTATGGACACTTGGAGCAATCCACTGGAGGAACGCAATC
ACCAAAGTCTTATTCCATTGGAAAAGGCCCAGGGCCCCTTCTTGTTTATTGTTGGCATGGATGA
TCAAAACTGGAAGAGTGAATTCTACGCTCAGATAGCCTCTGAAAGGCTACAAGCTCACGGGAAA
GAAAGACCCCAGATAATCTGTTACCCAGAAACAGGTCACTGTATTGACCCACCTTATTTTCCTC
CTTCTAGAGCCTCTGTGCATGCTGTTTTGGGTGAGACAGTATTCTATGGAGGTGAGCCAAAGGC
TCACTCAAAGGCACAGGTAGATGCCTGGCAGCAAATTCAAACTTTCTTCCGTAAACATCTCAAT
GGTAAAAAATGTGTCAAGCACAGCAAAATATAACATTGCAGCCACAGACCAGATACCATTAATA
AAAATCCTATTCATACAACTC

hide sequence

RefSeq Acc Id:

XM_007987229 ⟹ XP_007985420

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	24	50,827,238 - 50,834,462 (+)	NCBI
Vero_WHO_p1.0	NW_023666053	39,008,730 - 39,016,103 (+)	NCBI

Sequence:

show sequence

CAAGCGCGACTTTCTCCAACCGGGGGTGCGGCGCGAGCCGGTGCGCGCGGGCCGGGTGCGCGCC
GCGCTCTTCCTGCCGCCGGATTTGAAGACCTCCCTGAAGATCTGAATGATGTACATCTGGAGTA
CTTTGAAGAAGCCGTGGACTTTATGCTGCAGCATCCAGAGGTGAAAGGTCCTAGTATTGGGCTT
CTTGGATTTTCCAAAGGAGGTGACCTGTGTCTCTCAATGGCTTCTTTCTTGAAGGGCATCACAG
CCACTGTTCTTATCAATGCCTGTGTAGCCAACACCATAACTCCTCTACATTACAAGGATATGAT
TATTCCTAAACTTGTCGATGATCTAGGAAAAGTAAAAATCACGAAGTCAGGATTTCTCACTTTT
ATGGACACTTGGAGCAATCCACTGGAGGAACGCAATCACCAAAGTCTTATTCCATTGGAAAAGG
CCCAGGGCCCCTTCTTGTTTATTGTTGGCATGGATGATCAAAACTGGAAGAGTGAATTCTACGC
TCAGATAGCCTCTGAAAGGCTACAAGCTCACGGGAAAGAAAGACCCCAGATAATCTGTTACCCA
GAAACAGGTCACTGTATTGACCCACCTTATTTTCCTCCTTCTAGAGCCTCTGTGCATGCTGTTT
TGGGTGAGACAGTATTCTATGGAGGTGAGCCAAAGGCTCACTCAAAGGCACAGGTAGATGCCTG
GCAGCAAATTCAAACTTTCTTCCGTAAACATCTCAATGGTAAAAAATGTGTCAAGCACAGCAAA
ATATAACATTGCAGCCACAGACCAGATACCATTAATAAAAATCCTATTCATACAACTC

hide sequence

Protein Sequences


Protein RefSeqs	XP_007985419	(Get FASTA)	NCBI Sequence Viewer
	XP_007985420	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000019070.1

RefSeq Acc Id:	XP_007985419 ⟸ XM_007987228
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_007985420 ⟸ XM_007987229
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9SDY1 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000019571	UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000019661.1	UniProtKB/TrEMBL
Gene3D-CATH	alpha/beta hydrolase	UniProtKB/TrEMBL
InterPro	AB_hydrolase	UniProtKB/TrEMBL
	BAAT_C	UniProtKB/TrEMBL
NCBI Gene	ACOT6	ENTREZGENE
PANTHER	ACYL-COENZYME A THIOESTERASE 6-RELATED	UniProtKB/TrEMBL
	ACYL-COENZYME A THIOESTERASE-RELATED	UniProtKB/TrEMBL
Pfam	BAAT_C	UniProtKB/TrEMBL
Superfamily-SCOP	alpha/beta-Hydrolases	UniProtKB/TrEMBL
UniProt	A0A0D9SDY1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD