AEBP2 (AE binding protein 2) - Rat Genome Database

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Gene: AEBP2 (AE binding protein 2) Chlorocebus sabaeus
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Symbol: AEBP2
Name: AE binding protein 2
RGD ID: 18641604
Description: ENCODES a protein that exhibits transcription coregulator activity (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH genetic disease (ortholog); Hirschsprung's disease (ortholog); Waardenburg syndrome (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc finger protein AEBP2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11119,288,551 - 19,401,925 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1119,288,493 - 19,374,301 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606915,752,746 - 15,865,180 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
AEBP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11119,288,551 - 19,401,925 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1119,288,493 - 19,374,301 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606915,752,746 - 15,865,180 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
AEBP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381219,404,072 - 19,522,227 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1219,404,045 - 19,720,801 (+)EnsemblGRCh38hg38GRCh38
GRCh371219,592,426 - 19,675,161 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361219,483,900 - 19,564,846 (+)NCBINCBI36Build 36hg18NCBI36
Build 341219,483,899 - 19,564,845NCBI
Celera1224,745,851 - 24,829,274 (+)NCBICelera
Cytogenetic Map12p12.3NCBI
HuRef1219,361,681 - 19,444,406 (+)NCBIHuRef
CHM1_11219,558,199 - 19,640,737 (+)NCBICHM1_1
T2T-CHM13v2.01219,280,830 - 19,399,011 (+)NCBIT2T-CHM13v2.0
Aebp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396140,567,480 - 140,624,198 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6140,546,644 - 140,713,010 (+)EnsemblGRCm39 Ensembl
GRCm386140,622,454 - 140,678,472 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6140,622,663 - 140,678,472 (+)EnsemblGRCm38mm10GRCm38
MGSCv376140,571,184 - 140,625,939 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366140,585,069 - 140,639,824 (+)NCBIMGSCv36mm8
Celera6143,668,935 - 143,740,627 (+)NCBICelera
Cytogenetic Map6G2NCBI
cM Map670.71NCBI
Aebp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84175,258,286 - 175,297,149 (+)NCBIGRCr8
mRatBN7.24173,527,881 - 173,566,033 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4173,528,344 - 173,593,100 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4179,823,344 - 179,860,945 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04175,607,547 - 175,645,144 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04174,228,112 - 174,265,711 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04174,799,378 - 174,863,260 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4174,810,959 - 174,863,260 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04239,031,912 - 239,094,663 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44177,821,215 - 177,876,673 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14178,028,657 - 178,089,785 (+)NCBI
Celera4162,087,101 - 162,139,793 (+)NCBICelera
Cytogenetic Map4q44NCBI
Aebp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541315,495,073 - 15,561,227 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541315,514,247 - 15,561,233 (+)NCBIChiLan1.0ChiLan1.0
AEBP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21024,884,711 - 25,045,660 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11224,881,473 - 25,005,854 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01219,440,493 - 19,522,549 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11219,825,465 - 19,907,462 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1219,825,465 - 19,907,462 (+)Ensemblpanpan1.1panPan2
AEBP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12727,654,141 - 27,722,922 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2727,656,406 - 27,722,433 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2718,726,338 - 18,820,890 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02727,963,731 - 28,059,654 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2727,970,883 - 28,059,557 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12727,812,537 - 27,907,188 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02727,795,952 - 27,891,792 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02718,431,183 - 18,526,580 (+)NCBIUU_Cfam_GSD_1.0
Aebp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494588,905,278 - 88,967,401 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365486,810,002 - 6,889,614 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365486,828,190 - 6,890,287 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AEBP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl553,617,358 - 53,691,509 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1553,617,362 - 53,691,487 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2556,913,021 - 56,987,152 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Aebp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475218,956,481 - 19,023,620 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475218,954,095 - 19,023,656 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 22 44
Low 14 20 16
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000006137   ⟹   ENSCSAP00000004347
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1119,288,493 - 19,374,301 (+)Ensembl
RefSeq Acc Id: XM_007967841   ⟹   XP_007966032
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11119,288,552 - 19,372,645 (+)NCBI
Vero_WHO_p1.0NW_02366606915,781,825 - 15,865,180 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007967842   ⟹   XP_007966033
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11119,288,552 - 19,401,925 (+)NCBI
Vero_WHO_p1.0NW_02366606915,752,746 - 15,865,180 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007967847   ⟹   XP_007966038
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11119,288,551 - 19,371,320 (+)NCBI
Vero_WHO_p1.0NW_02366606915,781,825 - 15,865,174 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007967849   ⟹   XP_007966040
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11119,289,237 - 19,372,645 (+)NCBI
Vero_WHO_p1.0NW_02366606915,781,825 - 15,864,432 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007966032 (Get FASTA)   NCBI Sequence Viewer  
  XP_007966033 (Get FASTA)   NCBI Sequence Viewer  
  XP_007966038 (Get FASTA)   NCBI Sequence Viewer  
  XP_007966040 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004347
  ENSCSAP00000004347.1
RefSeq Acc Id: XP_007966038   ⟸   XM_007967847
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007966033   ⟸   XM_007967842
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007966032   ⟸   XM_007967841
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R6V8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007966040   ⟸   XM_007967849
- Peptide Label: isoform X4
RefSeq Acc Id: ENSCSAP00000004347   ⟸   ENSCSAT00000006137


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008085 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006137.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene AEBP2 ENTREZGENE
PANTHER ZINC FINGER PROTEIN AEBP2 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN AEBP2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A0D9R6V8 ENTREZGENE, UniProtKB/TrEMBL