PDXK (pyridoxal kinase) - Rat Genome Database

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Gene: PDXK (pyridoxal kinase) Chlorocebus sabaeus
Analyze
Symbol: PDXK
Name: pyridoxal kinase
RGD ID: 18638960
Description: ENCODES a protein that exhibits organic cyclic compound binding (ortholog); phosphotransferase activity, alcohol group as acceptor (ortholog); pyridoxal binding (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); pyridoxal metabolic process (ortholog); pyridoxal phosphate biosynthetic process (ortholog); PARTICIPATES IN hypophosphatasia pathway; vitamin B6 metabolic pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pyridoxal (pyridoxine, vitamin B6) kinase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1287,489,249 - 87,534,376 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl287,489,315 - 87,531,621 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605415,561,891 - 15,606,396 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PDXK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1287,489,249 - 87,534,376 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl287,489,315 - 87,531,621 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605415,561,891 - 15,606,396 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PDXK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382143,737,000 - 43,738,097 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2143,719,094 - 43,762,307 (+)EnsemblGRCh38hg38GRCh38
GRCh372145,138,978 - 45,182,188 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362143,963,406 - 44,006,616 (+)NCBINCBI36Build 36hg18NCBI36
Build 342143,963,405 - 44,006,608NCBI
Celera2130,244,819 - 30,287,780 (+)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2130,506,765 - 30,550,585 (+)NCBIHuRef
CHM1_12144,717,696 - 44,718,791 (+)NCBICHM1_1
T2T-CHM13v2.02142,092,543 - 42,093,640 (+)NCBIT2T-CHM13v2.0
Pdxk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391078,272,581 - 78,300,782 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1078,272,578 - 78,300,809 (-)EnsemblGRCm39 Ensembl
GRCm381078,436,747 - 78,464,948 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1078,436,744 - 78,464,975 (-)EnsemblGRCm38mm10GRCm38
MGSCv371077,899,492 - 77,927,693 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361077,842,099 - 77,868,104 (-)NCBIMGSCv36mm8
Celera1079,458,844 - 79,487,046 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Pdxk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82010,209,975 - 10,232,012 (+)NCBIGRCr8
mRatBN7.22010,210,276 - 10,232,314 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2010,210,289 - 10,232,110 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2010,909,956 - 10,931,608 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02010,270,865 - 10,292,517 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02010,742,295 - 10,763,997 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02010,930,651 - 10,952,194 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2010,930,518 - 10,952,391 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02013,102,429 - 13,123,972 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42010,541,656 - 10,563,199 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12010,541,882 - 10,563,426 (+)NCBI
Celera2011,721,159 - 11,742,702 (+)NCBICelera
Cytogenetic Map20p12NCBI
Pdxk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540741,482,216 - 41,494,177 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540741,482,216 - 41,494,174 (-)NCBIChiLan1.0ChiLan1.0
PDXK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22239,727,200 - 39,771,206 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12134,577,814 - 34,621,766 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02129,977,286 - 30,021,266 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12143,276,660 - 43,319,866 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2143,273,237 - 43,313,637 (+)Ensemblpanpan1.1panPan2
Pdxk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497136,928,712 - 36,956,834 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936500509,510 - 529,455 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936500510,977 - 539,166 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
Pdxk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474530,157,446 - 30,175,803 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474530,157,446 - 30,175,905 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000005999   ⟹   ENSCSAP00000004211
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl287,489,315 - 87,531,621 (+)Ensembl
RefSeq Acc Id: XM_007969539   ⟹   XP_007967730
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1287,503,468 - 87,534,376 (+)NCBI
Vero_WHO_p1.0NW_02366605415,571,804 - 15,606,396 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007969544   ⟹   XP_007967735
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1287,489,249 - 87,534,376 (+)NCBI
Vero_WHO_p1.0NW_02366605415,561,891 - 15,606,383 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007967730 (Get FASTA)   NCBI Sequence Viewer  
  XP_007967735 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004211
  ENSCSAP00000004211.1
RefSeq Acc Id: XP_007967735   ⟸   XM_007969544
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R6H2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007967730   ⟸   XM_007969539
- Peptide Label: isoform X1
Ensembl Acc Id: ENSCSAP00000004211   ⟸   ENSCSAT00000005999


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000007949 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000005999.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.1190.20 UniProtKB/TrEMBL
InterPro PM/HMP-P_kinase-1 UniProtKB/TrEMBL
  PyrdxlKinase UniProtKB/TrEMBL
  Ribokinase-like UniProtKB/TrEMBL
NCBI Gene PDXK ENTREZGENE
PANTHER PTHR10534 UniProtKB/TrEMBL
  PYRIDOXAL KINASE UniProtKB/TrEMBL
Pfam Phos_pyr_kin UniProtKB/TrEMBL
Superfamily-SCOP SSF53613 UniProtKB/TrEMBL
UniProt A0A0D9R6H2 ENTREZGENE, UniProtKB/TrEMBL