BMP8A (bone morphogenetic protein 8a) - Rat Genome Database

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Gene: BMP8A (bone morphogenetic protein 8a) Chlorocebus sabaeus
Analyze
Symbol: BMP8A
Name: bone morphogenetic protein 8a
RGD ID: 18638916
Description: ENCODES a protein that exhibits cytokine activity (inferred); growth factor activity (inferred); INVOLVED IN diet induced thermogenesis (ortholog); energy homeostasis (ortholog); germ cell development (ortholog); ASSOCIATED WITH Acute Otitis Media (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); genetic disease (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: bone morphogenetic protein 8B-like; LOC103225049; uncharacterized protein LOC103225049
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12093,102,468 - 93,133,875 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603323,436,850 - 23,470,879 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BMP8A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12093,102,468 - 93,133,875 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603323,436,850 - 23,470,879 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
BMP8A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38139,491,636 - 39,529,869 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl139,491,636 - 39,529,869 (+)EnsemblGRCh38hg38GRCh38
GRCh37139,957,308 - 39,995,541 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36139,729,905 - 39,768,128 (+)NCBINCBI36Build 36hg18NCBI36
Build 34139,626,410 - 39,660,700NCBI
Celera138,238,694 - 38,277,383 (+)NCBICelera
Cytogenetic Map1p34.3NCBI
HuRef138,076,358 - 38,114,746 (+)NCBIHuRef
CHM1_1140,073,204 - 40,111,431 (+)NCBICHM1_1
T2T-CHM13v2.0139,359,546 - 39,398,241 (+)NCBIT2T-CHM13v2.0
Bmp8a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394123,206,438 - 123,237,045 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4123,206,438 - 123,237,045 (-)EnsemblGRCm39 Ensembl
GRCm384123,312,645 - 123,343,252 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4123,312,645 - 123,343,252 (-)EnsemblGRCm38mm10GRCm38
MGSCv374122,989,888 - 123,020,046 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364122,814,948 - 122,845,106 (-)NCBIMGSCv36mm8
Celera4121,645,017 - 121,675,333 (-)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map457.42NCBI
Bmp8a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85140,874,942 - 140,902,881 (-)NCBIGRCr8
mRatBN7.25135,589,839 - 135,617,785 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5135,591,716 - 135,617,785 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5138,297,599 - 138,323,720 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05140,067,563 - 140,093,682 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05140,074,710 - 140,100,831 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05141,007,462 - 141,033,511 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5141,007,462 - 141,033,511 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05144,797,125 - 144,823,640 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45142,627,733 - 142,653,782 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5134,130,213 - 134,156,308 (-)NCBICelera
Cytogenetic Map5q36NCBI
LOC100984543
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21187,300,838 - 187,335,381 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11186,427,733 - 186,473,022 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0138,776,557 - 38,815,210 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1140,122,134 - 40,138,165 (+)NCBIpanpan1.1PanPan1.1panPan2
Bmp8a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505855,579,406 - 55,597,786 (+)NCBIHiC_Itri_2
BMP8A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1695,322,454 - 95,366,546 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2688,407,104 - 88,449,938 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_007979294   ⟹   XP_007977485
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12093,102,468 - 93,133,875 (+)NCBI
Vero_WHO_p1.0NW_02366603323,436,850 - 23,470,879 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007977485 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000016878.1
Reference Protein Sequences
RefSeq Acc Id: XP_007977485   ⟸   XM_007979294
- UniProtKB: A0A0D9S7N9 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000001136 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000017397.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.970 UniProtKB/TrEMBL
  Cystine-knot cytokines UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  TGF-b_C UniProtKB/TrEMBL
  TGF-b_propeptide UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/TrEMBL
  TGFb_CS UniProtKB/TrEMBL
NCBI Gene LOC103225049 ENTREZGENE
PANTHER BONE MORPHOGENETIC PROTEIN 8A-RELATED UniProtKB/TrEMBL
  TGF-BETA FAMILY UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/TrEMBL
  TGFb_propeptide UniProtKB/TrEMBL
PRINTS INHIBINA UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/TrEMBL
SMART TGFB UniProtKB/TrEMBL
Superfamily-SCOP Cystine-knot cytokines UniProtKB/TrEMBL
UniProt A0A0D9S7N9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 BMP8A  bone morphogenetic protein 8a  LOC103225049  bone morphogenetic protein 8B-like  Symbol and/or name change 5135510 APPROVED