SMTNL1 (smoothelin like 1) - Rat Genome Database

Name: SMTNL1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: SMTNL1 (smoothelin like 1) Chlorocebus sabaeus

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Symbol:

SMTNL1

Name:

smoothelin like 1

RGD ID:

18638184

Description:

ENCODES a protein that exhibits calmodulin binding (inferred); CH domain binding (inferred); disordered domain specific binding (inferred); INVOLVED IN muscle organ morphogenesis (ortholog); peptidyl-serine phosphorylation (ortholog); positive regulation of vasoconstriction (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN contractile muscle fiber (inferred); cytoplasm (inferred); I band (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

smoothelin-like protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SMTNL1 (smoothelin like 1)	NCBI	Ortholog
Mus musculus (house mouse):	Smtnl1 (smoothelin-like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Smtnl1 (smoothelin-like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Smtnl1 (smoothelin like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SMTNL1 (smoothelin like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SMTNL1 (smoothelin like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Smtnl1 (smoothelin like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SMTNL1 (smoothelin like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Smtnl1 (smoothelin like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	15,682,270 - 15,697,126 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	15,679,502 - 15,696,462 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	113,036,406 - 113,044,258 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

muscle organ morphogenesis (IEA,ISO)

negative regulation of DNA-templated transcription (IEA)

peptidyl-serine phosphorylation (ISO)

positive regulation of vasoconstriction (IEA,ISO)

response to activity (IEA,ISO)

response to xenobiotic stimulus (IEA,ISO)

vasoconstriction (IEA,ISO)

Cellular Component

contractile muscle fiber (IEA)

cytoplasm (IEA)

I band (IEA)

M band (IEA)

nucleus (IEA)

Molecular Function

calmodulin binding (IEA)

CH domain binding (IEA)

disordered domain specific binding (IEA)

protein binding (ISO)

protein phosphatase 1 binding (IEA)

tropomyosin binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SMTNL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	15,682,270 - 15,697,126 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	15,679,502 - 15,696,462 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	113,036,406 - 113,044,258 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

SMTNL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	57,537,595 - 57,550,272 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	57,537,595 - 57,550,272 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	57,305,068 - 57,317,745 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	57,065,555 - 57,074,684 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	54,666,633 - 54,674,266 (+)	NCBI		Celera
Cytogenetic Map	11	q12.1	NCBI
HuRef	11	53,658,903 - 53,666,539 (+)	NCBI		HuRef
CHM1_1	11	57,176,354 - 57,183,988 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	57,487,765 - 57,500,440 (+)	NCBI		T2T-CHM13v2.0

Smtnl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	84,641,494 - 84,657,173 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	84,641,520 - 84,652,996 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	84,811,173 - 84,826,847 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	84,811,176 - 84,822,652 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	84,651,333 - 84,662,809 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	84,612,015 - 84,623,491 (-)	NCBI		MGSCv36	mm8
Celera	2	86,406,709 - 86,421,097 (-)	NCBI		Celera
Cytogenetic Map	2	D	NCBI
cM Map	2	49.45	NCBI

Smtnl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	90,295,682 - 90,307,769 (-)	NCBI		GRCr8
mRatBN7.2	3	69,889,010 - 69,901,096 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	69,889,010 - 69,901,079 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	73,270,699 - 73,278,699 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	81,869,366 - 81,877,366 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	79,628,355 - 79,636,353 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	72,207,150 - 72,219,209 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	72,207,113 - 72,219,246 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	78,728,182 - 78,740,150 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	68,017,296 - 68,025,299 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	67,913,666 - 67,921,671 (-)	NCBI
Celera	3	69,248,302 - 69,252,187 (-)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

Smtnl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955511	2,515,651 - 2,521,077 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955511	2,512,950 - 2,521,200 (+)	NCBI	ChiLan1.0	ChiLan1.0

SMTNL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	58,692,926 - 58,706,659 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	59,713,177 - 59,725,017 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	52,777,777 - 52,792,165 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	56,250,161 - 56,262,842 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	56,255,219 - 56,262,685 (+)	Ensembl	panpan1.1		panPan2

SMTNL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	38,620,810 - 38,632,580 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	38,621,066 - 38,628,762 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	38,166,926 - 38,178,671 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	39,302,779 - 39,314,560 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	39,303,092 - 39,314,489 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	38,885,372 - 38,897,148 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	38,459,013 - 38,470,701 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	39,089,411 - 39,101,187 (-)	NCBI		UU_Cfam_GSD_1.0

Smtnl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	14,841,247 - 14,851,914 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936581	4,955,071 - 4,965,785 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936581	4,955,072 - 4,965,760 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SMTNL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	2	13,370,920 - 13,384,843 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Smtnl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624864	3,114,210 - 3,121,831 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007998305	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007998314	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007998322	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000004019 ⟹ ENSCSAP00000002288

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	1	15,679,502 - 15,696,462 (-)	Ensembl

RefSeq Acc Id:

XM_007998322 ⟹ XP_007996513

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	1	15,682,270 - 15,690,803 (-)	NCBI
Vero_WHO_p1.0	NW_023666038	113,036,406 - 113,044,258 (-)	NCBI

Sequence:

show sequence

CAGTGGCTTAATCAAAAAGAGGCAACATGACTGAAAAGGCATTATGTGACTCAATGTTCTTTAA
AGCCAAAGCCAGAACCTACAGAGGGGCATCAGGTGAATATCATCCAACATCACATCAATGTAGC
CCAACAATCCCAGCTTCGGGGAAGCACTTCTCTGTCCTTCATGCCTGGGTCTCATGTCCAAGTA
GGAGCCAAGACTGAACCACGGACTTCCTGACTCCCAGACCAGAGCTCTCTGAGGATGGGGTCTT
CACCTCATGCTGGGATGGGGCATGACCAGGTCTGCTTGTCTTCTCTTTCCAGAGATGGAGCAGA
AGGAAGGGAAGCCCTCTGAGGATGGGACCACCGTCTCCCCAGTTGCAGACAACCCTGAGATGTC
AGGAGGTGGAGCCCCTGCAGAGGAGACCAAAGGCACAGCTGGAAAGGCCATCAATGAGGGGCCT
CCTGCCGAGGCAGGAAAGCAGGAAAAGGCACCAGCCGAGGATGGCATTTCAGCAGAACTCCAGG
GGGAAGCAAATGGATTAGATGAGGTCAAGGTGGAATCTCAGACGGAGGCTGGTGGGAAACAGGA
CGCTGAGGCTGAACTTAAAGAGGAGGATGGTGAGAAGGAAGAGACCACTGCGGCTTCTCAGGAG
ATGACTGGCAGGAAAGAAGAGACCAAATCTGAACCCAAGGAGGCTGAGGAAAAGAAGGAGAGCA
TACTGGCCTCTGAGAAGCAGAAGGCGGAGGAGAAAGAGGCCAAACCTGAATCTGGGCAGAAAGT
CGAAGCCAACGACAGAGACAAGCCTGAACCTAAGGAAACTGTTGAGGAGGAGGAGGCCAAGACA
GCCTCTCAGGAGGAGACAGGCCAGAGGGAGAAGCGCAGCACTGAACCCAAGGAGAAGGCTACTG
ACGAAGAGGCCAAGGCTGAATCACAGAAGAAGGCTGTTGTGGAGGATGAGGCTAAGGCTGAACC
CAAGGAGTCTGATGGGAAAGAGGAGGCCAAACATGATACAACAAAGGAGGCTGATGCAAAGGAG
GAGGTGGAGGAGGCGGAGGAGGCAGAGCCAGGCAGTCCCAGTGAAGAGCAGGAGCAGGACGTGG
AAAAAGAGCCAGAGGGAGGGGCAGGGGTGCTTCCCAGCTCCCCAGAGGAGTGGCCTGAGAGCCC
CACGGGGGAGGGGCACAACCTCAGCACAGATGGGTTGGGTCCAGACTCCGTAGCTTCTGGAGAG
ACCAGTCCTTCAGCCAGTGAGTCTTCACCCAGCGATGTGCCCCAGAGTCCCCCTGAGTCCCCTC
CCTCAGGGGAGAAGAAGGAGAAGGCACCAGAGCGCAGGGTATCAGCCCCTGCTCGGCCCCGGGG
GCCCCGAGCACAGAACCGCAAAGCCATCGTGGACAAGTTTGGCGGGGCAGCGTCTGGCCCTACG
GCCCTGTTCCGGAACACTAAGGCAGCTGGGGCAGCCATTGGTGGTGTCAAGAACATGCTCTTGG
AGTGGTGCCGAGCCATGACAAAAAAATACGAGCACGTGGACATCCAGAACTTCTCCTCCAGCTG
GAGCAGTGGCATGGCCTTCTGTGCCCTCATCCACAAGTTCTTCCCTGACGCCTTTGACTACGCA
GAGCTGGACCCCACGAAGCGCCGGCACAACTTCACCCTGGCCTTCTCCACAGCAGAGAAACTGG
CTGACTGTGCTCAGCTGCTGGACGTGGATGACATGGTGCGGTTGGCTGTGCCCGACTCCAAGTG
CGTCTACACCTACATCCAGGAACTGTACCGCAGCCTCGTGCAGAAAGGACTGGTGAAGACCAAG
AAGAAATGAGGAGGTGACTGCCTCTGTGGGCAGAGATG

hide sequence

Protein Sequences


Protein RefSeqs	XP_007996513	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000002288.1

RefSeq Acc Id:	XP_007996513 ⟸ XM_007998322
- UniProtKB:	A0A0D9R0Z9 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000002288 ⟸ ENSCSAT00000004019

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000005982	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000004019.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.418.10	UniProtKB/TrEMBL
InterPro	CH-domain	UniProtKB/TrEMBL
	CH_dom_sf	UniProtKB/TrEMBL
	F-actin_Monoox_Mical	UniProtKB/TrEMBL
NCBI Gene	SMTNL1	ENTREZGENE
PANTHER	CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED	UniProtKB/TrEMBL
	SMOOTHELIN-LIKE PROTEIN 1	UniProtKB/TrEMBL
Pfam	PF00307	UniProtKB/TrEMBL
PROSITE	PS50021	UniProtKB/TrEMBL
SMART	SM00033	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47576	UniProtKB/TrEMBL
UniProt	A0A0D9R0Z9	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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