ALDH3A2 (aldehyde dehydrogenase 3 family member A2) - Rat Genome Database

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Gene: ALDH3A2 (aldehyde dehydrogenase 3 family member A2) Chlorocebus sabaeus
Analyze
Symbol: ALDH3A2
Name: aldehyde dehydrogenase 3 family member A2
RGD ID: 18630414
Description: ENCODES a protein that exhibits 3-chloroallyl aldehyde dehydrogenase activity (ortholog); INVOLVED IN formaldehyde metabolic process (ortholog); response to reactive oxygen species (ortholog); sesquiterpenoid metabolic process (ortholog); PARTICIPATES IN phytanic acid degradation pathway; Refsum disease pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); common variable immunodeficiency 2 (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); peroxisome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: aldehyde dehydrogenase family 3 member A2; fatty aldehyde dehydrogenase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11618,213,284 - 18,241,261 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1618,213,487 - 18,239,271 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660592,605,746 - 2,633,744 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ALDH3A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11618,213,284 - 18,241,261 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1618,213,487 - 18,239,271 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660592,605,746 - 2,633,744 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ALDH3A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381719,648,136 - 19,677,596 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1719,648,136 - 19,685,760 (+)EnsemblGRCh38hg38GRCh38
GRCh371719,551,449 - 19,580,909 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361719,492,656 - 19,521,500 (+)NCBINCBI36Build 36hg18NCBI36
Build 341719,492,682 - 19,521,495NCBI
Celera1716,965,422 - 16,994,253 (+)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1718,931,182 - 18,960,005 (+)NCBIHuRef
CHM1_11719,560,917 - 19,589,757 (+)NCBICHM1_1
T2T-CHM13v2.01719,596,758 - 19,626,215 (+)NCBIT2T-CHM13v2.0
Aldh3a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391161,114,240 - 61,158,267 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1161,114,243 - 61,158,290 (-)EnsemblGRCm39 Ensembl
GRCm381161,223,417 - 61,267,528 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1161,223,417 - 61,267,464 (-)EnsemblGRCm38mm10GRCm38
MGSCv371161,058,257 - 61,080,629 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361161,060,950 - 61,083,322 (-)NCBIMGSCv36mm8
MGSCv361161,674,448 - 61,696,820 (-)NCBIMGSCv36mm8
Cytogenetic Map11B2NCBI
cM Map1137.96NCBI
Aldh3a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81046,427,789 - 46,448,449 (-)NCBIGRCr8
mRatBN7.21045,928,313 - 45,949,366 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1045,908,524 - 45,949,281 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1050,630,818 - 50,651,382 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01050,121,209 - 50,141,773 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01045,624,781 - 45,645,345 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01047,525,486 - 47,546,535 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1047,525,493 - 47,546,345 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01047,300,324 - 47,321,002 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41047,400,518 - 47,421,064 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11047,414,148 - 47,434,687 (-)NCBI
Celera1045,182,182 - 45,202,711 (-)NCBICelera
Cytogenetic Map10q22NCBI
Aldh3a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955467140,760 - 162,742 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955467141,592 - 162,376 (-)NCBIChiLan1.0ChiLan1.0
ALDH3A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21954,640,441 - 54,683,013 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11759,452,286 - 59,494,725 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01731,455,386 - 31,482,985 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11736,599,830 - 36,628,102 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1736,599,835 - 36,628,102 (-)Ensemblpanpan1.1panPan2
ALDH3A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1540,515,768 - 40,641,377 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl540,515,030 - 40,641,463 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha540,657,648 - 40,782,777 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0540,621,779 - 40,644,870 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0540,676,970 - 40,739,907 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1540,593,134 - 40,717,947 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0540,538,776 - 40,664,129 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0540,731,446 - 40,856,529 (-)NCBIUU_Cfam_GSD_1.0
Aldh3a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560260,436,975 - 60,460,173 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936881127,023 - 150,292 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936881127,090 - 150,269 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALDH3A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1259,936,848 - 59,954,358 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11259,936,838 - 59,953,677 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21262,591,931 - 62,608,903 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Aldh3a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248495,912,273 - 5,938,007 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248495,911,711 - 5,941,706 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 14 59
Low 6 1
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000005901   ⟹   ENSCSAP00000004117
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1618,213,487 - 18,239,271 (+)Ensembl
RefSeq Acc Id: XM_008010628   ⟹   XP_008008819
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11618,213,499 - 18,239,345 (+)NCBI
Vero_WHO_p1.0NW_0236660592,607,564 - 2,633,549 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008010629   ⟹   XP_008008820
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11618,213,284 - 18,241,261 (+)NCBI
Vero_WHO_p1.0NW_0236660592,605,746 - 2,633,744 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008010631   ⟹   XP_008008822
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11618,213,549 - 18,241,261 (+)NCBI
Vero_WHO_p1.0NW_0236660592,605,869 - 2,633,537 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037987212   ⟹   XP_037843140
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660592,605,925 - 2,633,569 (-)NCBI
RefSeq Acc Id: XM_037987213   ⟹   XP_037843141
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660592,607,564 - 2,633,534 (-)NCBI
RefSeq Acc Id: XP_008008820   ⟸   XM_008010629
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R678 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008008819   ⟸   XM_008010628
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008008822   ⟸   XM_008010631
- Peptide Label: isoform X3
RefSeq Acc Id: ENSCSAP00000004117   ⟸   ENSCSAT00000005901
RefSeq Acc Id: XP_037843140   ⟸   XM_037987212
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037843141   ⟸   XM_037987213
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000007853 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000005901.1 UniProtKB/TrEMBL
InterPro Ald_DH/histidinol_DH UniProtKB/TrEMBL
  Ald_DH_C UniProtKB/TrEMBL
  Ald_DH_CS_CYS UniProtKB/TrEMBL
  Ald_DH_CS_GLU UniProtKB/TrEMBL
  Ald_DH_N UniProtKB/TrEMBL
  Aldehyde_DH_dom UniProtKB/TrEMBL
  Aldehyde_DH_NAD(P) UniProtKB/TrEMBL
NCBI Gene ALDH3A2 ENTREZGENE
PANTHER ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER A2 UniProtKB/TrEMBL
  PTHR43570 UniProtKB/TrEMBL
Pfam Aldedh UniProtKB/TrEMBL
PIRSF ALDH UniProtKB/TrEMBL
PROSITE ALDEHYDE_DEHYDR_CYS UniProtKB/TrEMBL
  ALDEHYDE_DEHYDR_GLU UniProtKB/TrEMBL
Superfamily-SCOP SSF53720 UniProtKB/TrEMBL
UniProt A0A0D9R678 ENTREZGENE, UniProtKB/TrEMBL