LOC103234208 (BLOC-1-related complex subunit 8) - Rat Genome Database

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Gene: LOC103234208 (BLOC-1-related complex subunit 8) Chlorocebus sabaeus
Analyze
Symbol: LOC103234208 (Ensembl: BORCS8)
Name: BLOC-1-related complex subunit 8 (Ensembl:BLOC-1 related complex subunit 8)
RGD ID: 18627149
Description: INVOLVED IN heart development (inferred); ASSOCIATED WITH genetic disease (ortholog); Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1 (ortholog); progressive myoclonus epilepsy 8 (ortholog); FOUND IN BORC complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BLOC-1 related complex subunit 8; BORCS8; LOC103234209; myocyte-specific enhancer factor 2B; protein MEF2BNB
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,648,714 - 17,660,931 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl617,648,758 - 17,660,877 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660741,651,620 - 1,707,912 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC103234208
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,648,714 - 17,660,931 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl617,648,758 - 17,660,877 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660741,651,620 - 1,707,912 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
BORCS8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381919,176,906 - 19,192,152 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1919,176,903 - 19,192,591 (-)EnsemblGRCh38hg38GRCh38
GRCh371919,287,715 - 19,302,961 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361919,153,685 - 19,164,425 (-)NCBINCBI36Build 36hg18NCBI36
Celera1919,192,547 - 19,208,203 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,851,509 - 18,867,171 (-)NCBIHuRef
CHM1_11919,288,223 - 19,303,916 (-)NCBICHM1_1
T2T-CHM13v2.01919,313,447 - 19,328,701 (-)NCBIT2T-CHM13v2.0
Borcs8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,592,149 - 70,601,285 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,592,149 - 70,599,969 (+)EnsemblGRCm39 Ensembl
GRCm38870,139,499 - 70,148,635 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,139,499 - 70,147,319 (+)EnsemblGRCm38mm10GRCm38
MGSCv37872,663,612 - 72,671,160 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,069,266 - 73,076,308 (+)NCBIMGSCv36mm8
Celera872,695,151 - 72,702,730 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Borcs8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,308,247 - 19,314,910 (-)NCBIGRCr8
mRatBN7.21619,274,305 - 19,280,969 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1619,274,023 - 19,280,339 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1619,314,091 - 19,320,754 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,446,197 - 20,452,876 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,367,050 - 19,373,713 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01621,022,500 - 21,029,163 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1621,023,996 - 21,029,134 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,872,444 - 20,879,034 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,757,638 - 19,764,480 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1619,462,947 - 19,469,545 (-)NCBICelera
Cytogenetic Map16p14NCBI
Borcs8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,641,907 - 2,646,275 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555242,641,907 - 2,646,275 (+)NCBIChiLan1.0ChiLan1.0
BORCS8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22024,044,251 - 24,054,336 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11923,025,584 - 23,060,632 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01918,615,221 - 18,630,230 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11919,590,791 - 19,632,239 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,617,791 - 19,632,239 (-)Ensemblpanpan1.1panPan2
BORCS8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12043,983,476 - 43,994,575 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2043,984,075 - 43,992,955 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2043,900,881 - 43,911,653 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02044,471,896 - 44,482,668 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,472,200 - 44,482,668 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12043,708,999 - 43,719,851 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,118,780 - 44,129,548 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02044,394,268 - 44,404,907 (+)NCBIUU_Cfam_GSD_1.0
Borcs8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118202,682,803 - 202,693,447 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,231,954 - 2,242,919 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,232,183 - 2,242,267 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BORCS8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl258,684,543 - 58,698,173 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1258,684,508 - 58,696,586 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Borcs8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249082,081,229 - 2,089,913 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249082,082,745 - 2,089,666 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 13 59
Low 7 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000003245   ⟹   ENSCSAP00000001531
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl617,648,758 - 17,660,877 (-)Ensembl
RefSeq Acc Id: XM_007995872   ⟹   XP_007994063
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660741,695,220 - 1,707,912 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007995875   ⟹   XP_007994066
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660741,680,210 - 1,707,912 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007995879   ⟹   XP_007994070
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660741,680,211 - 1,707,907 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037992231   ⟹   XP_037848159
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660741,651,818 - 1,707,907 (+)NCBI
RefSeq Acc Id: XM_037992233   ⟹   XP_037848161
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660741,651,812 - 1,707,912 (+)NCBI
RefSeq Acc Id: XM_037992234   ⟹   XP_037848162
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660741,657,508 - 1,707,912 (+)NCBI
RefSeq Acc Id: XM_037992235   ⟹   XP_037848163
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660741,651,848 - 1,707,912 (+)NCBI
RefSeq Acc Id: XM_037992236   ⟹   XP_037848164
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660741,651,620 - 1,674,017 (+)NCBI
RefSeq Acc Id: XM_037992237   ⟹   XP_037848165
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660741,651,620 - 1,702,486 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000001531   ⟸   ENSCSAT00000003245
RefSeq Acc Id: XP_037848165   ⟸   XM_037992237
- Peptide Label: isoform X6
- UniProtKB: A0A0D9QYU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037848164   ⟸   XM_037992236
- Peptide Label: isoform X6
- UniProtKB: A0A0D9QYU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037848161   ⟸   XM_037992233
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037848159   ⟸   XM_037992231
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037848163   ⟸   XM_037992235
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037848162   ⟸   XM_037992234
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007994066   ⟸   XM_007995875
- Peptide Label: isoform X4
RefSeq Acc Id: XP_007994070   ⟸   XM_007995879
- Peptide Label: isoform X5
RefSeq Acc Id: XP_007994063   ⟸   XM_007995872
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005214 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003245.1 UniProtKB/TrEMBL
InterPro BORCS8 UniProtKB/TrEMBL
NCBI Gene BORCS8 ENTREZGENE
PANTHER BLOC-1-RELATED COMPLEX SUBUNIT 8 UniProtKB/TrEMBL
  PTHR21146 UniProtKB/TrEMBL
Pfam BORCS8 UniProtKB/TrEMBL
UniProt A0A0D9QYU2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 LOC103234208  BLOC-1-related complex subunit 8  BORCS8  BLOC-1 related complex subunit 8  Symbol and/or name change 5135510 APPROVED
2020-12-03 BORCS8  BLOC-1 related complex subunit 8  LOC103234209  myocyte-specific enhancer factor 2B  Data merged from RGD:18744594 737654 PROVISIONAL