GABPB1 (GA binding protein transcription factor subunit beta 1) - Rat Genome Database

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Gene: GABPB1 (GA binding protein transcription factor subunit beta 1) Chlorocebus sabaeus
Analyze
Symbol: GABPB1
Name: GA binding protein transcription factor subunit beta 1
RGD ID: 18613592
Description: ENCODES a protein that exhibits transcription cis-regulatory region binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); genetic disease (ortholog); FOUND IN cytoplasmic ribonucleoprotein granule (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: GA binding protein transcription factor beta subunit 1; GA-binding protein subunit beta-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12632,967,912 - 33,039,114 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2633,008,209 - 33,039,689 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048108,110,456 - 108,182,710 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GABPB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12632,967,912 - 33,039,114 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2633,008,209 - 33,039,689 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048108,110,456 - 108,182,710 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
GABPB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381550,275,389 - 50,355,198 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1550,275,389 - 50,355,408 (-)EnsemblGRCh38hg38GRCh38
GRCh371550,567,586 - 50,647,395 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361548,356,681 - 48,434,687 (-)NCBINCBI36Build 36hg18NCBI36
Build 341548,365,374 - 48,434,687NCBI
Celera1527,461,979 - 27,540,178 (-)NCBICelera
Cytogenetic Map15q21.2NCBI
HuRef1527,400,324 - 27,478,454 (-)NCBIHuRef
CHM1_11550,687,328 - 50,765,436 (-)NCBICHM1_1
T2T-CHM13v2.01548,083,628 - 48,163,356 (-)NCBIT2T-CHM13v2.0
Gabpb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392126,470,832 - 126,527,184 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2126,469,362 - 126,518,257 (-)EnsemblGRCm39 Ensembl
GRCm382126,628,907 - 126,684,435 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2126,627,442 - 126,676,337 (-)EnsemblGRCm38mm10GRCm38
MGSCv372126,454,649 - 126,501,223 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362126,320,354 - 126,366,928 (-)NCBIMGSCv36mm8
Celera2127,867,260 - 127,913,380 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map261.76NCBI
Gabpb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83134,333,339 - 134,380,239 (-)NCBIGRCr8
mRatBN7.23113,879,972 - 113,924,742 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3113,879,973 - 113,923,696 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3117,763,645 - 117,808,243 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03126,359,180 - 126,403,776 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03124,019,556 - 124,064,151 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03119,091,739 - 119,135,391 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,091,744 - 119,135,391 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03125,617,852 - 125,661,431 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43114,153,730 - 114,197,849 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3112,722,551 - 112,766,206 (-)NCBICelera
Cytogenetic Map3q36NCBI
Gabpb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554094,004,480 - 4,039,681 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554093,983,857 - 4,036,433 (+)NCBIChiLan1.0ChiLan1.0
GABPB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21639,515,370 - 39,611,754 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11543,699,514 - 43,779,270 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01529,223,588 - 29,303,863 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11547,545,767 - 47,627,957 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1547,547,202 - 47,600,234 (-)Ensemblpanpan1.1panPan2
GABPB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13016,239,321 - 16,303,701 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3016,240,677 - 16,303,701 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3016,165,398 - 16,230,041 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03016,383,196 - 16,447,861 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3016,382,276 - 16,447,576 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13016,305,719 - 16,370,374 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03016,423,353 - 16,487,863 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03016,529,799 - 16,594,315 (-)NCBIUU_Cfam_GSD_1.0
Gabpb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864094,492,265 - 94,554,158 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647112,340,134 - 12,368,706 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647112,340,328 - 12,402,236 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABPB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1121,413,506 - 121,489,806 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11121,410,276 - 121,488,165 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21135,053,552 - 135,129,309 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Gabpb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247319,761,507 - 9,822,159 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 12 8 26
Low 24 12 34
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000009045   ⟹   ENSCSAP00000007177
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2633,008,209 - 33,039,689 (+)Ensembl
RefSeq Acc Id: XM_008016631   ⟹   XP_008014822
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12632,967,927 - 33,039,114 (+)NCBI
Vero_WHO_p1.0NW_023666048108,110,456 - 108,182,710 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008016632   ⟹   XP_008014823
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12632,967,925 - 33,039,114 (+)NCBI
Vero_WHO_p1.0NW_023666048108,110,456 - 108,182,710 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008016636   ⟹   XP_008014827
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12632,967,929 - 33,039,114 (+)NCBI
Vero_WHO_p1.0NW_023666048108,110,456 - 108,182,710 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008016637   ⟹   XP_008014828
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12632,967,912 - 33,039,114 (+)NCBI
Vero_WHO_p1.0NW_023666048108,110,456 - 108,182,710 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038009974   ⟹   XP_037865902
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666048108,110,456 - 108,182,710 (-)NCBI
RefSeq Acc Id: XM_038009975   ⟹   XP_037865903
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666048108,110,456 - 108,182,710 (-)NCBI
RefSeq Acc Id: XM_038009976   ⟹   XP_037865904
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666048108,110,456 - 108,182,710 (-)NCBI
RefSeq Acc Id: XP_008014828   ⟸   XM_008016637
- Peptide Label: isoform X4
RefSeq Acc Id: XP_008014823   ⟸   XM_008016632
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008014822   ⟸   XM_008016631
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008014827   ⟸   XM_008016636
- Peptide Label: isoform X3
- UniProtKB: A0A0D9REY8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000007177   ⟸   ENSCSAT00000009045
RefSeq Acc Id: XP_037865904   ⟸   XM_038009976
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037865902   ⟸   XM_038009974
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037865903   ⟸   XM_038009975
- Peptide Label: isoform X3
- UniProtKB: A0A0D9REY8 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010961 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009045.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
NCBI Gene GABPB1 ENTREZGENE
PANTHER ANKYRIN REPEAT PROTEIN UniProtKB/TrEMBL
  GA-BINDING PROTEIN SUBUNIT BETA-1 UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  Ank_4 UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt A0A0D9REY8 ENTREZGENE, UniProtKB/TrEMBL