GPR37 (G protein-coupled receptor 37) - Rat Genome Database

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Gene: GPR37 (G protein-coupled receptor 37) Chlorocebus sabaeus
Analyze
Symbol: GPR37
Name: G protein-coupled receptor 37
RGD ID: 18609265
Description: ENCODES a protein that exhibits heat shock protein binding (ortholog); Hsp70 protein binding (ortholog); neuropeptide binding (ortholog); INVOLVED IN cellular response to reactive oxygen species (ortholog); dendrite development (ortholog); dopamine biosynthetic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); Lewy body dementia (ortholog); malignant mesothelioma (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: prosaposin receptor GPR37
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12193,487,178 - 93,507,317 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2193,486,702 - 93,507,056 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660429,949,159 - 9,971,276 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
GPR37
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12193,487,178 - 93,507,317 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2193,486,702 - 93,507,056 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660429,949,159 - 9,971,276 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
GPR37
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387124,743,885 - 124,765,792 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7124,743,885 - 124,765,792 (-)EnsemblGRCh38hg38GRCh38
GRCh377124,383,939 - 124,405,846 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367124,173,350 - 124,192,917 (-)NCBINCBI36Build 36hg18NCBI36
Build 347123,980,066 - 123,999,632NCBI
Celera7119,191,362 - 119,210,932 (-)NCBICelera
Cytogenetic Map7q31.33NCBI
HuRef7118,750,711 - 118,771,098 (-)NCBIHuRef
CHM1_17124,318,797 - 124,339,217 (-)NCBICHM1_1
T2T-CHM13v2.07126,061,240 - 126,083,145 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27123,775,046 - 123,795,470 (-)NCBI
Gpr37
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39625,668,522 - 25,689,979 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl625,665,877 - 25,690,728 (-)EnsemblGRCm39 Ensembl
GRCm38625,668,523 - 25,689,980 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl625,665,878 - 25,690,729 (-)EnsemblGRCm38mm10GRCm38
MGSCv37625,618,523 - 25,639,980 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36625,618,118 - 25,640,739 (-)NCBIMGSCv36mm8
Celera625,669,443 - 25,690,900 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
cM Map611.65NCBI
Gpr37
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8455,104,355 - 55,126,420 (-)NCBIGRCr8
mRatBN7.2454,138,860 - 54,160,927 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl454,138,870 - 54,161,001 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx459,140,517 - 59,162,546 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0455,054,096 - 55,076,127 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0453,458,667 - 53,480,642 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0451,822,163 - 51,844,228 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl451,822,153 - 51,844,331 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0451,598,203 - 51,620,268 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4452,166,918 - 52,188,983 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1452,397,493 - 52,419,557 (-)NCBI
Celera449,276,912 - 49,299,393 (-)NCBICelera
Cytogenetic Map4q22NCBI
Gpr37
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554796,057,276 - 6,080,994 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554796,061,424 - 6,080,129 (-)NCBIChiLan1.0ChiLan1.0
GPR37
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26161,593,816 - 161,613,989 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1713,604,066 - 13,624,239 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07116,727,912 - 116,751,647 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17129,410,462 - 129,430,292 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7129,410,458 - 129,430,292 (-)Ensemblpanpan1.1panPan2
GPR37
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11411,113,584 - 11,137,639 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1411,114,415 - 11,132,395 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1410,812,992 - 10,835,790 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01410,895,712 - 10,918,523 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1410,896,513 - 10,918,510 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11411,087,569 - 11,110,364 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01410,819,644 - 10,842,429 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01410,979,393 - 11,002,189 (+)NCBIUU_Cfam_GSD_1.0
Gpr37
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511851,206,369 - 51,225,767 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936605978,980 - 999,741 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936605978,174 - 997,093 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPR37
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1823,019,749 - 23,038,356 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11823,019,752 - 23,036,483 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21824,665,384 - 24,682,115 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Gpr37
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478311,291,497 - 11,320,952 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478311,291,601 - 11,319,467 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36
Low 11 9 13
Below cutoff 25 8 11

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007982793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000008334   ⟹   ENSCSAP00000006484
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2193,486,702 - 93,507,056 (-)Ensembl
RefSeq Acc Id: XM_007982793   ⟹   XP_007980984
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12193,487,178 - 93,507,317 (-)NCBI
Vero_WHO_p1.0NW_0236660429,949,159 - 9,971,276 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007980984 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000006484
  ENSCSAP00000006484.1
Reference Protein Sequences
RefSeq Acc Id: XP_007980984   ⟸   XM_007982793
- UniProtKB: A0A0D9RCZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000006484   ⟸   ENSCSAT00000008334


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010249 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008334.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  GPR37_orph UniProtKB/TrEMBL
KEGG Report csab:103226828 UniProtKB/TrEMBL
NCBI Gene GPR37 ENTREZGENE
PANTHER PROSAPOSIN RECEPTOR GPR37 UniProtKB/TrEMBL
  PTHR46216 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  GPR37ORPHANR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0D9RCZ5 ENTREZGENE, UniProtKB/TrEMBL