FBXO38 (F-box protein 38) - Rat Genome Database

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Gene: FBXO38 (F-box protein 38) Chlorocebus sabaeus
Analyze
Symbol: FBXO38
Name: F-box protein 38
RGD ID: 18601526
Description: INVOLVED IN positive regulation of neuron projection development (inferred); positive regulation of T cell mediated immune response to tumor cell (inferred); protein K48-linked ubiquitination (inferred); ASSOCIATED WITH autosomal dominant distal hereditary motor neuronopathy 2 (ortholog); autosomal dominant distal hereditary motor neuronopathy 6 (ortholog); Charcot-Marie-Tooth disease (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box only protein 38
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12351,020,119 - 51,079,317 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2351,020,127 - 51,079,308 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603426,675,742 - 26,734,991 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FBXO38
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12351,020,119 - 51,079,317 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2351,020,127 - 51,079,308 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603426,675,742 - 26,734,991 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FBXO38
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385148,383,958 - 148,442,836 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5148,383,935 - 148,442,836 (+)EnsemblGRCh38hg38GRCh38
GRCh375147,763,521 - 147,822,399 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365147,743,739 - 147,802,592 (+)NCBINCBI36Build 36hg18NCBI36
Celera5143,842,908 - 143,901,761 (+)NCBICelera
Cytogenetic Map5q32NCBI
HuRef5142,910,539 - 142,969,456 (+)NCBIHuRef
CHM1_15147,196,208 - 147,255,098 (+)NCBICHM1_1
T2T-CHM13v2.05148,918,479 - 148,977,363 (+)NCBIT2T-CHM13v2.0
Fbxo38
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391862,637,130 - 62,681,934 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1862,637,226 - 62,681,766 (-)EnsemblGRCm39 Ensembl
GRCm381862,504,059 - 62,548,863 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1862,504,155 - 62,548,695 (-)EnsemblGRCm38mm10GRCm38
MGSCv371862,663,713 - 62,708,397 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361862,629,529 - 62,674,083 (-)NCBIMGSCv36mm8
Celera1863,775,869 - 63,823,039 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1835.11NCBI
Fbxo38
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81858,227,253 - 58,274,320 (-)NCBIGRCr8
mRatBN7.21855,956,950 - 56,004,013 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1855,956,959 - 56,003,961 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1858,050,603 - 58,097,662 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01858,764,902 - 58,811,954 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01856,580,810 - 56,627,813 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01857,827,391 - 57,874,515 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1857,827,392 - 57,866,741 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01857,053,464 - 57,100,790 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41858,517,371 - 58,564,412 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11858,590,970 - 58,629,285 (-)NCBI
Celera1854,102,507 - 54,149,633 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
Fbxo38
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554155,841,038 - 5,889,110 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554155,841,269 - 5,888,830 (-)NCBIChiLan1.0ChiLan1.0
FBXO38
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24143,597,425 - 143,678,187 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15141,736,975 - 141,817,462 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05143,814,446 - 143,873,919 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15149,823,271 - 149,882,592 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5149,834,109 - 149,881,903 (+)Ensemblpanpan1.1panPan2
FBXO38
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1460,360,543 - 60,416,727 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl460,320,648 - 60,417,205 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha460,124,736 - 60,180,903 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0460,849,108 - 60,905,329 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl460,848,833 - 60,905,299 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1460,629,374 - 60,685,535 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0460,756,046 - 60,812,233 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0461,274,359 - 61,330,551 (-)NCBIUU_Cfam_GSD_1.0
Fbxo38
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213144,745,057 - 144,795,548 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365046,318,940 - 6,369,480 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365046,319,026 - 6,369,487 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO38
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2149,674,448 - 149,722,865 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12149,674,300 - 149,722,875 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22156,358,976 - 156,406,051 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Fbxo38
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247747,798,369 - 7,850,056 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247747,798,407 - 7,849,840 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 6 45
Low 14 15
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000009982   ⟹   ENSCSAP00000008084
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2351,020,127 - 51,079,308 (+)Ensembl
RefSeq Acc Id: XM_008014906   ⟹   XP_008013097
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12351,020,125 - 51,079,317 (+)NCBI
Vero_WHO_p1.0NW_02366603426,675,742 - 26,734,991 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008014907   ⟹   XP_008013098
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12351,020,125 - 51,079,041 (+)NCBI
Vero_WHO_p1.0NW_02366603426,675,742 - 26,734,991 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008014908   ⟹   XP_008013099
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12351,020,119 - 51,079,317 (+)NCBI
Vero_WHO_p1.0NW_02366603426,675,742 - 26,734,991 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008014910   ⟹   XP_008013101
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12351,020,119 - 51,079,317 (+)NCBI
Vero_WHO_p1.0NW_02366603426,675,904 - 26,734,991 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038006213   ⟹   XP_037862141
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603426,675,742 - 26,734,822 (-)NCBI
RefSeq Acc Id: XP_008013099   ⟸   XM_008014908
- Peptide Label: isoform X3
RefSeq Acc Id: XP_008013101   ⟸   XM_008014910
- Peptide Label: isoform X4
RefSeq Acc Id: XP_008013097   ⟸   XM_008014906
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RHJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008013098   ⟸   XM_008014907
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000008084   ⟸   ENSCSAT00000009982
RefSeq Acc Id: XP_037862141   ⟸   XM_038006213
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RHJ5 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011896 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009982.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  FBX38 UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103244763 UniProtKB/TrEMBL
NCBI Gene FBXO38 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 38 UniProtKB/TrEMBL
  PTHR14753 UniProtKB/TrEMBL
Pfam F-box UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
  SSF81383 UniProtKB/TrEMBL
UniProt A0A0D9RHJ5 ENTREZGENE, UniProtKB/TrEMBL