ERI1 (exoribonuclease 1) - Rat Genome Database

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Gene: ERI1 (exoribonuclease 1) Chlorocebus sabaeus
Analyze
Symbol: ERI1
Name: exoribonuclease 1
RGD ID: 18596101
Description: ENCODES a protein that exhibits histone pre-mRNA stem-loop binding (ortholog); ribosome binding (ortholog); rRNA binding (ortholog); INVOLVED IN histone mRNA catabolic process (ortholog); maturation of 5.8S rRNA (ortholog); rRNA 3'-end processing (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH amenorrhea (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN histone pre-mRNA 3'end processing complex (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 3'-5' exoribonuclease 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.189,936,951 - 10,055,407 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl810,023,909 - 10,055,405 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605232,340,126 - 32,459,216 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ERI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.189,936,951 - 10,055,407 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl810,023,909 - 10,055,405 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605232,340,126 - 32,459,216 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ERI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3889,002,897 - 9,100,104 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl89,002,147 - 9,116,746 (+)EnsemblGRCh38hg38GRCh38
GRCh3788,860,407 - 8,957,614 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3688,897,860 - 8,925,899 (+)NCBINCBI36Build 36hg18NCBI36
Celera87,988,552 - 8,019,088 (+)NCBICelera
Cytogenetic Map8p23.1NCBI
HuRef87,785,390 - 7,815,914 (+)NCBIHuRef
CHM1_188,925,749 - 8,956,251 (+)NCBICHM1_1
T2T-CHM13v2.0810,644,016 - 10,741,931 (-)NCBIT2T-CHM13v2.0
Eri1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39835,932,419 - 35,962,687 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl835,932,407 - 35,963,350 (-)EnsemblGRCm39 Ensembl
GRCm38835,465,265 - 35,495,533 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl835,465,253 - 35,496,196 (-)EnsemblGRCm38mm10GRCm38
MGSCv37836,528,319 - 36,558,587 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36836,933,770 - 36,963,998 (-)NCBIMGSCv36mm8
Celera838,105,540 - 38,129,667 (-)NCBICelera
Cytogenetic Map8A4NCBI
cM Map821.16NCBI
Eri1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81663,427,412 - 63,447,521 (+)NCBIGRCr8
mRatBN7.21656,724,101 - 56,744,228 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1656,724,115 - 56,744,226 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1662,035,775 - 62,055,838 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01665,449,758 - 65,469,821 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01660,669,734 - 60,689,797 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01660,307,148 - 60,327,237 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1660,307,148 - 60,327,236 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01659,982,385 - 60,002,474 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41660,422,764 - 60,442,317 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11660,422,838 - 60,442,391 (+)NCBI
Celera1654,774,309 - 54,794,398 (+)NCBICelera
Cytogenetic Map16q12.2NCBI
Eri1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554635,075,105 - 5,102,892 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554635,074,921 - 5,104,341 (+)NCBIChiLan1.0ChiLan1.0
ERI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2725,348,156 - 25,490,392 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan181,444,510 - 1,524,637 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0810,175,556 - 10,249,904 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ERI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11635,441,304 - 35,499,501 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1635,473,913 - 35,499,487 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1635,905,778 - 35,963,974 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01637,473,637 - 37,531,847 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1637,504,230 - 37,531,795 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11635,579,052 - 35,637,366 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01636,142,393 - 36,200,661 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01636,261,126 - 36,319,266 (-)NCBIUU_Cfam_GSD_1.0
Eri1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494343,667,231 - 43,695,456 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365731,448,325 - 1,474,753 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1556,093,581 - 56,123,510 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11556,091,790 - 56,123,520 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Eri1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248395,090,369 - 5,118,775 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248395,090,187 - 5,119,985 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 36 20 60
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000014961   ⟹   ENSCSAP00000012917
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl810,023,909 - 10,055,405 (-)Ensembl
RefSeq Acc Id: XM_007961679   ⟹   XP_007959870
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1810,026,850 - 10,055,402 (-)NCBI
Vero_WHO_p1.0NW_02366605232,340,126 - 32,369,401 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007961680   ⟹   XP_007959871
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.189,936,951 - 10,055,407 (-)NCBI
Vero_WHO_p1.0NW_02366605232,340,126 - 32,459,216 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007961682   ⟹   XP_007959873
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.189,982,150 - 10,055,405 (-)NCBI
Vero_WHO_p1.0NW_02366605232,340,126 - 32,413,910 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007961683   ⟹   XP_007959874
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1810,024,085 - 10,055,404 (-)NCBI
Vero_WHO_p1.0NW_02366605232,340,126 - 32,372,256 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007961684   ⟹   XP_007959875
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1810,024,004 - 10,055,404 (-)NCBI
Vero_WHO_p1.0NW_02366605232,340,126 - 32,372,256 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037983795   ⟹   XP_037839723
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605232,340,126 - 32,421,260 (+)NCBI
RefSeq Acc Id: XP_007959871   ⟸   XM_007961680
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007959873   ⟸   XM_007961682
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007959875   ⟸   XM_007961684
- Peptide Label: isoform X4
RefSeq Acc Id: XP_007959874   ⟸   XM_007961683
- Peptide Label: isoform X4
RefSeq Acc Id: XP_007959870   ⟸   XM_007961679
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RWC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000012917   ⟸   ENSCSAT00000014961
RefSeq Acc Id: XP_037839723   ⟸   XM_037983795
- Peptide Label: isoform X5


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016866 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014961.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.720.30 UniProtKB/TrEMBL
  3.30.420.10 UniProtKB/TrEMBL
InterPro ERI-1_3'hExo-like UniProtKB/TrEMBL
  Exonuclease_RNaseT/DNA_pol3 UniProtKB/TrEMBL
  RNaseH-like_sf UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/TrEMBL
  SAP_dom UniProtKB/TrEMBL
  SAP_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103215357 UniProtKB/TrEMBL
NCBI Gene ERI1 ENTREZGENE
PANTHER 3'-5' EXONUCLEASE ERI1-RELATED UniProtKB/TrEMBL
  3'-5' EXORIBONUCLEASE 1 UniProtKB/TrEMBL
Pfam RNase_T UniProtKB/TrEMBL
  SAP UniProtKB/TrEMBL
PROSITE SAP UniProtKB/TrEMBL
SMART EXOIII UniProtKB/TrEMBL
  SAP UniProtKB/TrEMBL
Superfamily-SCOP SSF53098 UniProtKB/TrEMBL
  SSF68906 UniProtKB/TrEMBL
UniProt A0A0D9RWC8 ENTREZGENE, UniProtKB/TrEMBL