ASTN2 (astrotactin 2) - Rat Genome Database

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Gene: ASTN2 (astrotactin 2) Chlorocebus sabaeus
Analyze
Symbol: ASTN2
Name: astrotactin 2
RGD ID: 18594857
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); INVOLVED IN establishment of body hair planar orientation (ortholog); negative regulation of protein localization to cell surface (ortholog); protein localization to cell surface (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); autistic disorder (ortholog); autosomal recessive limb-girdle muscular dystrophy (ortholog); FOUND IN cell pole (ortholog); endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: astrotactin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11222,176,073 - 23,155,638 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1222,177,637 - 23,156,979 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603519,723,218 - 20,710,501 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell pole  (ISO)
endosome  (IEA,ISO)
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ASTN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11222,176,073 - 23,155,638 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1222,177,637 - 23,156,979 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603519,723,218 - 20,710,501 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ASTN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389116,423,112 - 117,415,057 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9116,423,112 - 117,415,070 (-)EnsemblGRCh38hg38GRCh38
GRCh379119,185,391 - 120,177,335 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369118,227,328 - 119,217,138 (-)NCBINCBI36Build 36hg18NCBI36
Celera989,835,176 - 90,825,037 (-)NCBICelera
Cytogenetic Map9q33.1NCBI
HuRef988,793,045 - 89,344,120 (-)NCBIHuRef
HuRef989,381,724 - 89,795,414 (-)NCBIHuRef
CHM1_19119,333,901 - 120,324,897 (-)NCBICHM1_1
T2T-CHM13v2.09128,616,101 - 129,608,884 (-)NCBIT2T-CHM13v2.0
Astn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39465,299,040 - 66,322,774 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl465,299,040 - 66,322,848 (-)EnsemblGRCm39 Ensembl
GRCm38465,380,803 - 66,404,537 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl465,380,803 - 66,404,611 (-)EnsemblGRCm38mm10GRCm38
MGSCv37465,041,837 - 66,065,517 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36464,867,164 - 65,890,844 (-)NCBIMGSCv36mm8
Celera464,014,026 - 65,026,874 (-)NCBICelera
Cytogenetic Map4C1NCBI
cM Map434.31NCBI
Astn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8583,772,988 - 84,759,439 (-)NCBIGRCr8
mRatBN7.2578,758,142 - 79,744,021 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl578,758,142 - 79,748,273 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx581,149,458 - 82,124,079 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0582,966,735 - 83,941,362 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0582,942,167 - 83,916,952 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0581,179,614 - 82,168,528 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl581,179,605 - 82,168,427 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0585,276,544 - 86,266,807 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4582,124,461 - 83,128,927 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1582,318,349 - 82,365,151 (-)NCBI
Celera577,680,743 - 78,656,297 (-)NCBICelera
Cytogenetic Map5q24NCBI
Astn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541910,486,118 - 11,390,085 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541910,486,200 - 11,387,553 (+)NCBIChiLan1.0ChiLan1.0
ASTN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21121,939,533 - 22,919,646 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1921,941,888 - 22,922,007 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0987,558,337 - 88,538,570 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19115,849,915 - 116,890,925 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9115,912,657 - 116,890,931 (-)Ensemblpanpan1.1panPan2
ASTN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11170,248,704 - 70,977,893 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1170,249,060 - 71,097,833 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1168,657,415 - 69,512,472 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01171,373,908 - 72,226,706 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1171,374,496 - 72,226,914 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11169,893,958 - 70,750,556 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01169,930,438 - 70,778,597 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01170,658,551 - 71,510,662 (-)NCBIUU_Cfam_GSD_1.0
Astn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947185,640,886 - 186,479,428 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364875,409,287 - 5,916,553 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364875,409,413 - 5,854,418 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASTN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1256,825,486 - 257,740,977 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11256,825,466 - 257,740,676 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21288,324,328 - 288,860,102 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Astn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476017,901,406 - 18,816,820 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476017,901,406 - 18,813,087 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 15 32
Low 21 12 28
Below cutoff 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000011221   ⟹   ENSCSAP00000009302
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1222,177,637 - 23,156,979 (+)Ensembl
RefSeq Acc Id: XM_007968250   ⟹   XP_007966441
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11222,176,075 - 23,155,638 (+)NCBI
Vero_WHO_p1.0NW_02366603519,723,218 - 20,710,500 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007968251   ⟹   XP_007966442
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11222,176,073 - 23,155,638 (+)NCBI
Vero_WHO_p1.0NW_02366603519,723,218 - 20,710,501 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007968252   ⟹   XP_007966443
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11222,176,073 - 23,155,638 (+)NCBI
Vero_WHO_p1.0NW_02366603519,723,218 - 20,710,501 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007968253   ⟹   XP_007966444
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11222,176,075 - 23,155,638 (+)NCBI
Vero_WHO_p1.0NW_02366603519,723,218 - 20,710,500 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007968254   ⟹   XP_007966445
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11222,907,402 - 23,155,638 (+)NCBI
Vero_WHO_p1.0NW_02366603519,723,218 - 19,970,489 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037982503   ⟹   XP_037838431
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603519,723,218 - 19,970,752 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007966443   ⟸   XM_007968252
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RL13 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007966442   ⟸   XM_007968251
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RL13 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007966441   ⟸   XM_007968250
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RL13 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007966444   ⟸   XM_007968253
- Peptide Label: isoform X4
- UniProtKB: A0A0D9RL13 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007966445   ⟸   XM_007968254
- Peptide Label: isoform X6
RefSeq Acc Id: ENSCSAP00000009302   ⟸   ENSCSAT00000011221
RefSeq Acc Id: XP_037838431   ⟸   XM_037982503
- Peptide Label: isoform X5


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013127 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011221.1 UniProtKB/TrEMBL
Gene3D-CATH Laminin UniProtKB/TrEMBL
InterPro Annexin-like UniProtKB/TrEMBL
  ASTN1_2_EGF_Fn UniProtKB/TrEMBL
  ASTN_1_2_N UniProtKB/TrEMBL
  ASTN_2_hairpin UniProtKB/TrEMBL
  Astrotactin UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  MACPF UniProtKB/TrEMBL
NCBI Gene ASTN2 ENTREZGENE
PANTHER ASTROTACTIN-2 UniProtKB/TrEMBL
  PTHR16592 UniProtKB/TrEMBL
Pfam Annexin_like UniProtKB/TrEMBL
  ASTN1_2_EGF_Fn UniProtKB/TrEMBL
  ASTN_1_2_N UniProtKB/TrEMBL
  ASTN_2_hairpin UniProtKB/TrEMBL
  MACPF UniProtKB/TrEMBL
SMART MACPF UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
UniProt A0A0D9RL13 ENTREZGENE, UniProtKB/TrEMBL