DEPP1 (DEPP autophagy regulator 1)

Gene: DEPP1 (DEPP autophagy regulator 1) Chlorocebus sabaeus

Analyze

Symbol:

DEPP1

Name:

DEPP autophagy regulator 1

RGD ID:

18594437

Description:

INVOLVED IN regulation of autophagy (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); COVID-19 (ortholog); endometriosis (ortholog); FOUND IN cytoplasm (inferred); intracellular membrane-bounded organelle (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

C9H10orf10; DEPP1 autophagy regulator; protein DEPP

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	40,602,193 - 40,603,791 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	40,602,223 - 40,602,861 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666056	45,800,538 - 45,802,078 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Breast Neoplasms (ISO)

COVID-19 (ISO)

endometriosis (ISO)

lipid storage disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

regulation of autophagy (IEA)

Cellular Component

cytoplasm (IEA)

intracellular membrane-bounded organelle (IEA)

mitochondrion (IEA)

peroxisome (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

DEPP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	40,602,193 - 40,603,791 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	40,602,223 - 40,602,861 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666056	45,800,538 - 45,802,078 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

DEPP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	44,976,128 - 44,978,809 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	44,970,981 - 44,978,809 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	45,471,576 - 45,474,257 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	44,791,715 - 44,794,336 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	44,791,716 - 44,794,263	NCBI
Celera	10	41,474,883 - 41,477,504 (-)	NCBI		Celera
Cytogenetic Map	10	q11.21	NCBI
HuRef	10	41,996,250 - 41,998,871 (-)	NCBI		HuRef
CHM1_1	10	45,510,686 - 45,513,307 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	45,857,092 - 45,859,773 (-)	NCBI		T2T-CHM13v2.0

Depp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	116,627,645 - 116,629,808 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	116,627,570 - 116,629,755 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	116,650,684 - 116,652,847 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	116,650,609 - 116,652,794 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	116,600,702 - 116,602,865 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	116,616,318 - 116,618,413 (+)	NCBI		MGSCv36	mm8
Celera	6	118,491,933 - 118,494,097 (+)	NCBI		Celera
Cytogenetic Map	6	E3	NCBI
cM Map	6	53.83	NCBI

Depp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	151,583,105 - 151,585,455 (+)	NCBI		GRCr8
mRatBN7.2	4	149,910,794 - 149,913,013 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	149,910,779 - 149,914,542 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	156,152,814 - 156,154,892 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	151,936,856 - 151,938,934 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	150,559,748 - 150,561,826 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	148,780,330 - 148,784,566 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	148,782,479 - 148,784,562 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	214,721,136 - 214,723,301 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	153,000,782 - 153,002,562 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	138,786,484 - 138,788,568 (+)	NCBI		Celera
Cytogenetic Map	4	q42	NCBI

Depp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955546	2,291,829 - 2,293,375 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955546	2,291,829 - 2,293,375 (-)	NCBI	ChiLan1.0	ChiLan1.0

DEPP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	57,712,084 - 57,713,637 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	57,717,413 - 57,718,929 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	41,970,914 - 41,973,518 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	45,150,510 - 45,153,157 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	45,151,636 - 45,152,280 (-)	Ensembl	panpan1.1		panPan2

DEPP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	2,463,770 - 2,465,240 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	2,464,584 - 2,465,210 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	2,699,175 - 2,700,647 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	2,642,640 - 2,644,112 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	2,643,452 - 2,644,078 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	2,441,206 - 2,442,678 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	2,478,478 - 2,479,950 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	2,609,647 - 2,611,119 (+)	NCBI		UU_Cfam_GSD_1.0

Depp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	82,041,955 - 82,043,912 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936617	4,740,103 - 4,740,741 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936617	4,740,073 - 4,743,610 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DEPP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	91,114,441 - 91,122,191 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	91,118,332 - 91,120,242 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	99,353,238 - 99,354,838 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Depp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004628729	538 - 1,142 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	16		16
Low	20	17	44
Below cutoff		3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007962493	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000018506 ⟹ ENSCSAP00000017958

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	9	40,602,223 - 40,602,861 (-)	Ensembl

RefSeq Acc Id:

XM_007962493 ⟹ XP_007960684

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	9	40,602,193 - 40,603,791 (-)	NCBI
Vero_WHO_p1.0	NW_023666056	45,800,538 - 45,802,078 (+)	NCBI

Sequence:

show sequence

TGGCAGAAAAACACCTCCAAGCGGGCAGCTGGGCCAGGCCCCGCCCACCAAGCTGTTTTCCTAA
GAGAGCCTTCCTGAGCAGGCTATTCTTGGTCCTCGTGACAGTGATTGATAGCTGGTGGGAAGGT
ATAAAAGCGGCTGCCTGCCGAAGCTCTTCAGACAGCTCAGGGAAGAGTCTGGCACGGTTTTCTT
TGAGACTCAGTGCACCGTCCTCCTCCCAGCGACCCCACCCTGGACCCCCTGCCGGACCCTCCAC
CCTTTGGCCTCCAAGCTTCCCAGGGGCTTCCTTTGGACTGGACTGTCCCTGCTCATCCATTCTC
CTGCCACCCCCAGACCTTCTCGGCTCCAGGTTGCCGCCTCCTCTCGCCAGAGTGATGAGGTCCC
GGCTTCTGCTCTCTGTGGCCCATCTGCCCACAATTCGGGAGACCACGGAGGAGATGCTGCTTGG
GGGTCCTGGGCAGGAGCCCCCGCCCTCTCCTAGCCTGGATGACTACGTGAGATCCATATCTCGA
CTGGCACAACCCACCTCTGTGCTGAACAAGGCCACGGCCCAGGGCCAACCCAGGCCACCCCACA
GGCCAGCCCAGGCCTGCCGGAAGGGCCGCCCTGCTGTGTCCCTGCGGGACATCACCGCACGTTT
CAGTGGCCAGCAGCCCACACTGCCCACGGCTGATGCTGTGGACCCCCTGGACTGGCTTTTTGGG
GAGTCCCAGGAAAAGCAGCCAAGCCAGAGGGACCTGCCGAGGAGGACTGGCCCCTCTGCTGGCC
TCTGGGGTCCGCACAGACAGATGGACAGCAGCAAGACCAGGGGGACCCCCAGAGGGAGGCTCTG
TGAAGCCAGGATGCCTGGGCACTCCCTAGCAAGACCATCGCGGGATGGGCAGCAGAGCTCTGAC
CTAAGAAGCTGGACTTTGGGGCAGCCTGCCCAAGCCATGGCCTCCCCCCGCAGCCCCCGCCCCA
GCAGTGTCCTCAGAACTCTCTACTCGCACCTCCCGGTGATCCATGAACTCTGACCCCTGCCCAA
TAAAGCCTTCTGTAAAGAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_007960684	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000017958
	ENSCSAP00000017958.1

RefSeq Acc Id:	XP_007960684 ⟸ XM_007962493
- UniProtKB:	A0A0D9SAR9 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000017958 ⟸ ENSCSAT00000018506

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000018416	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000018506.1	UniProtKB/TrEMBL
InterPro	DEPP	UniProtKB/TrEMBL
KEGG Report	csab:103215789	UniProtKB/TrEMBL
NCBI Gene	DEPP1	ENTREZGENE
PANTHER	PROTEIN DEPP1	UniProtKB/TrEMBL
	PTHR15426	UniProtKB/TrEMBL
Pfam	DEPP	UniProtKB/TrEMBL
UniProt	A0A0D9SAR9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-09-07	DEPP1	DEPP autophagy regulator 1	DEPP1	DEPP1 autophagy regulator	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD