GOPC (golgi associated PDZ and coiled-coil motif containing) - Rat Genome Database

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Gene: GOPC (golgi associated PDZ and coiled-coil motif containing) Chlorocebus sabaeus
Analyze
Symbol: GOPC
Name: golgi associated PDZ and coiled-coil motif containing
RGD ID: 18590928
Description: ENCODES a protein that exhibits frizzled binding (ortholog); GTPase regulator activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN spermatid nucleus differentiation (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); autistic disorder (ortholog); azoospermia (ortholog); FOUND IN plasma membrane (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: golgi-associated PDZ and coiled-coil motif-containing protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11356,229,780 - 56,270,829 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1356,229,810 - 56,272,830 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604028,567,387 - 28,608,428 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
GOPC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11356,229,780 - 56,270,829 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1356,229,810 - 56,272,830 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604028,567,387 - 28,608,428 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
GOPC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386117,560,269 - 117,602,511 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6117,560,269 - 117,602,542 (-)EnsemblGRCh38hg38GRCh38
GRCh376117,881,432 - 117,923,674 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366117,988,125 - 118,030,374 (-)NCBINCBI36Build 36hg18NCBI36
Build 346117,991,109 - 118,030,220NCBI
Celera6118,624,329 - 118,666,606 (-)NCBICelera
Cytogenetic Map6q22.1NCBI
HuRef6115,462,063 - 115,504,349 (-)NCBIHuRef
CHM1_16118,145,375 - 118,187,647 (-)NCBICHM1_1
T2T-CHM13v2.06118,744,505 - 118,786,752 (-)NCBIT2T-CHM13v2.0
Gopc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391052,213,120 - 52,258,220 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1052,211,946 - 52,258,220 (-)EnsemblGRCm39 Ensembl
GRCm381052,337,024 - 52,382,124 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1052,335,850 - 52,382,124 (-)EnsemblGRCm38mm10GRCm38
MGSCv371052,056,887 - 52,101,881 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361052,025,496 - 52,070,490 (-)NCBIMGSCv36mm8
Celera1053,174,463 - 53,219,811 (-)NCBICelera
Cytogenetic Map10B3NCBI
cM Map1026.54NCBI
Gopc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82032,270,314 - 32,319,635 (-)NCBIGRCr8
mRatBN7.22031,727,617 - 31,776,904 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2031,727,620 - 31,776,903 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2032,726,053 - 32,781,732 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02032,116,963 - 32,172,643 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02032,853,588 - 32,902,883 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02033,471,355 - 33,521,281 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2033,471,351 - 33,521,311 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02035,250,254 - 35,299,353 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42031,055,284 - 31,105,701 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12031,071,736 - 31,119,338 (-)NCBI
Celera2033,125,468 - 33,174,815 (-)NCBICelera
Cytogenetic Map20q11NCBI
Gopc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955436742,305 - 777,566 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955436743,616 - 777,878 (-)NCBIChiLan1.0ChiLan1.0
GOPC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25137,574,230 - 137,619,713 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16135,467,252 - 135,512,718 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06115,368,682 - 115,411,140 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16119,509,936 - 119,552,010 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6119,509,936 - 119,552,010 (-)Ensemblpanpan1.1panPan2
GOPC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1157,790,118 - 57,829,022 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl157,792,647 - 57,828,820 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha158,589,110 - 58,629,156 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0157,970,112 - 58,010,164 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl157,970,099 - 58,011,073 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1157,871,500 - 57,911,541 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0157,712,463 - 57,752,507 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0158,343,632 - 58,383,890 (-)NCBIUU_Cfam_GSD_1.0
Gopc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946108,509,927 - 108,548,999 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936658614,476 - 655,905 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936658614,711 - 655,874 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GOPC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl144,239,383 - 44,287,198 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1144,239,364 - 44,285,886 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2149,584,131 - 49,631,566 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Gopc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479812,188,635 - 12,218,305 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479812,188,460 - 12,216,542 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 1 53
Low 19 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000014142   ⟹   ENSCSAP00000012122
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1356,229,810 - 56,272,830 (+)Ensembl
RefSeq Acc Id: XM_008007228   ⟹   XP_008005419
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11356,229,780 - 56,270,829 (+)NCBI
Vero_WHO_p1.0NW_02366604028,567,387 - 28,608,428 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008007230   ⟹   XP_008005421
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11356,229,782 - 56,270,829 (+)NCBI
Vero_WHO_p1.0NW_02366604028,567,388 - 28,608,428 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008005419 (Get FASTA)   NCBI Sequence Viewer  
  XP_008005421 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012122
  ENSCSAP00000012122.1
Reference Protein Sequences
RefSeq Acc Id: XP_008005419   ⟸   XM_008007228
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RU33 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008005421   ⟸   XM_008007230
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000012122   ⟸   ENSCSAT00000014142


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016048 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014142.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
InterPro GOPC UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
KEGG Report csab:103240494 UniProtKB/TrEMBL
NCBI Gene GOPC ENTREZGENE
PANTHER GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING PROTEIN UniProtKB/TrEMBL
  PTHR16528 UniProtKB/TrEMBL
Pfam PDZ UniProtKB/TrEMBL
PROSITE PDZ UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
Superfamily-SCOP SSF50156 UniProtKB/TrEMBL
UniProt A0A0D9RU33 ENTREZGENE, UniProtKB/TrEMBL