IL36RN (interleukin 36 receptor antagonist) - Rat Genome Database

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Gene: IL36RN (interleukin 36 receptor antagonist) Chlorocebus sabaeus
Analyze
Symbol: IL36RN
Name: interleukin 36 receptor antagonist
RGD ID: 18583177
Description: ENCODES a protein that exhibits cytokine activity (inferred); interleukin-1 receptor binding (inferred); INVOLVED IN antifungal humoral response (ortholog); negative regulation of cytokine-mediated signaling pathway (ortholog); negative regulation of interleukin-17 production (ortholog); ASSOCIATED WITH Chediak-Higashi syndrome (ortholog); Deficiency of Interleukin-1 Receptor Antagonist (ortholog); endometriosis (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: interleukin-36 receptor antagonist protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11416,079,045 - 16,085,245 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1416,079,906 - 16,083,167 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660803,595,687 - 3,601,850 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
IL36RN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11416,079,045 - 16,085,245 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1416,079,906 - 16,083,167 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660803,595,687 - 3,601,850 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
IL36RN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382113,058,638 - 113,064,744 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2113,058,638 - 113,065,382 (+)EnsemblGRCh38hg38GRCh38
GRCh372113,816,215 - 113,822,321 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,532,686 - 113,538,792 (+)NCBINCBI36Build 36hg18NCBI36
Build 342113,532,445 - 113,538,549NCBI
Celera2107,201,384 - 107,207,490 (+)NCBICelera
Cytogenetic Map2q14.1NCBI
HuRef2106,271,122 - 106,277,233 (+)NCBIHuRef
CHM1_12113,820,366 - 113,826,472 (+)NCBICHM1_1
T2T-CHM13v2.02113,485,166 - 113,491,272 (+)NCBIT2T-CHM13v2.0
Il36rn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39224,166,966 - 24,172,444 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl224,166,966 - 24,173,438 (+)EnsemblGRCm39 Ensembl
GRCm38224,276,954 - 24,282,432 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl224,276,954 - 24,283,426 (+)EnsemblGRCm38mm10GRCm38
MGSCv37224,132,474 - 24,137,952 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36224,099,412 - 24,104,085 (+)NCBIMGSCv36mm8
Celera223,996,392 - 24,001,870 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map216.31NCBI
Il36rn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8327,442,679 - 27,449,306 (+)NCBIGRCr8
mRatBN7.237,044,419 - 7,051,016 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl37,044,406 - 7,051,016 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx310,155,713 - 10,162,310 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0318,741,940 - 18,748,537 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0316,931,750 - 16,938,347 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.031,385,256 - 1,392,275 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl31,385,654 - 1,392,275 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.031,378,833 - 1,385,430 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.432,530,402 - 2,536,999 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.132,520,904 - 2,534,765 (+)NCBI
Celera31,881,325 - 1,887,922 (+)NCBICelera
Cytogenetic Map3p13NCBI
Il36rn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554701,209,325 - 1,214,821 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554701,209,389 - 1,214,730 (-)NCBIChiLan1.0ChiLan1.0
IL36RN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21215,124,677 - 15,133,315 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A15,127,442 - 15,136,080 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A89,059,526 - 89,065,695 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A114,003,745 - 114,009,865 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A114,004,209 - 114,009,865 (+)Ensemblpanpan1.1panPan2
IL36RN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11737,184,527 - 37,190,094 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1737,184,801 - 37,189,018 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1736,954,558 - 36,960,118 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01737,961,425 - 37,966,985 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1737,960,679 - 37,965,143 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11737,096,825 - 37,102,385 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01737,153,330 - 37,158,890 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01737,367,110 - 37,372,667 (+)NCBIUU_Cfam_GSD_1.0
Il36rn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629282,509,294 - 82,510,160 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367831,401,482 - 1,404,416 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367831,396,720 - 1,404,416 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
Il36rn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474913,137,782 - 13,143,031 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474913,137,512 - 13,145,578 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system
High
Medium
Low 12
Below cutoff 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000014819   ⟹   ENSCSAP00000012780
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1416,079,906 - 16,083,167 (+)Ensembl
RefSeq Acc Id: XM_008008422   ⟹   XP_008006613
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11416,079,295 - 16,085,245 (+)NCBI
Vero_WHO_p1.0NW_0236660803,595,687 - 3,601,560 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008008423   ⟹   XP_008006614
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11416,079,045 - 16,085,245 (+)NCBI
Vero_WHO_p1.0NW_0236660803,595,687 - 3,601,850 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037994251   ⟹   XP_037850179
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660803,595,687 - 3,601,560 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008006613 (Get FASTA)   NCBI Sequence Viewer  
  XP_008006614 (Get FASTA)   NCBI Sequence Viewer  
  XP_037850179 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012780
  ENSCSAP00000012780.1
Reference Protein Sequences
RefSeq Acc Id: XP_008006614   ⟸   XM_008008423
- UniProtKB: A0A0D9RVZ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008006613   ⟸   XM_008008422
- UniProtKB: A0A0D9RVZ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000012780   ⟸   ENSCSAT00000014819
RefSeq Acc Id: XP_037850179   ⟸   XM_037994251
- UniProtKB: A0A0D9RVZ1 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016723 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014819.1 UniProtKB/TrEMBL
Gene3D-CATH 2.80.10.50 UniProtKB/TrEMBL
InterPro IL-1_CS UniProtKB/TrEMBL
  IL-1_fam UniProtKB/TrEMBL
  IL-1RA/IL-36 UniProtKB/TrEMBL
  IL1/FGF UniProtKB/TrEMBL
KEGG Report csab:103241285 UniProtKB/TrEMBL
NCBI Gene IL36RN ENTREZGENE
PANTHER PTHR10078 UniProtKB/TrEMBL
  PTHR10078:SF32 UniProtKB/TrEMBL
Pfam IL1 UniProtKB/TrEMBL
PRINTS INTERLEUKIN1 UniProtKB/TrEMBL
  INTRLEUKIN1X UniProtKB/TrEMBL
PROSITE INTERLEUKIN_1 UniProtKB/TrEMBL
SMART IL1 UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/TrEMBL
UniProt A0A0D9RVZ1 ENTREZGENE, UniProtKB/TrEMBL