FCGR1A (Fc fragment of IgG receptor Ia) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: FCGR1A (Fc fragment of IgG receptor Ia) Chlorocebus sabaeus
Analyze
Symbol: FCGR1A
Name: Fc fragment of IgG receptor Ia
RGD ID: 18579331
Description: ENCODES a protein that exhibits IgG binding (ortholog); IgG receptor activity (ortholog); leukotriene receptor binding (ortholog); INVOLVED IN antibody-dependent cellular cytotoxicity (ortholog); antigen processing and presentation of exogenous antigen (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); calcinosis (ortholog); Experimental Arthritis (ortholog); FOUND IN external side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: high affinity immunoglobulin gamma Fc receptor I; LOC103247163
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366603813,502,010 - 13,510,802 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FCGR1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366603813,502,010 - 13,510,802 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FCGR1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381149,782,694 - 149,800,609 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1149,782,671 - 149,791,675 (+)EnsemblGRCh38hg38GRCh38
GRCh371149,754,250 - 149,772,165 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361148,020,912 - 148,030,698 (+)NCBINCBI36Build 36hg18NCBI36
Build 341146,567,360 - 146,577,146NCBI
Cytogenetic Map1q21.2NCBI
CHM1_11151,150,820 - 151,160,644 (+)NCBICHM1_1
T2T-CHM13v2.01148,906,840 - 148,924,747 (+)NCBIT2T-CHM13v2.0
Fcgr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39396,190,225 - 96,201,285 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl396,190,225 - 96,201,285 (-)EnsemblGRCm39 Ensembl
GRCm38396,282,909 - 96,293,969 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl396,282,909 - 96,293,969 (-)EnsemblGRCm38mm10GRCm38
MGSCv37396,086,832 - 96,097,892 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36396,368,314 - 96,379,374 (-)NCBIMGSCv36mm8
Celera397,711,230 - 97,722,291 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map341.72NCBI
Fcgr1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82186,539,941 - 186,548,941 (-)NCBIGRCr8
mRatBN7.22183,851,075 - 183,860,077 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2183,851,077 - 183,859,994 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2191,514,627 - 191,523,542 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02189,313,778 - 189,322,712 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02184,147,164 - 184,156,079 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02198,430,536 - 198,439,453 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2198,430,530 - 198,458,041 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02217,916,295 - 217,925,212 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42191,095,026 - 191,103,942 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12191,057,780 - 191,066,696 (-)NCBI
Celera2176,378,627 - 176,387,543 (-)NCBICelera
Cytogenetic Map2q34NCBI
FCGR1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21100,047,861 - 100,056,851 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1199,802,796 - 99,811,784 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01125,127,073 - 125,136,911 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11128,805,436 - 128,815,227 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1128,805,484 - 128,814,220 (+)Ensemblpanpan1.1panPan2
FCGR1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11759,073,139 - 59,102,023 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1759,092,933 - 59,102,015 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1758,541,116 - 58,550,066 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01760,070,040 - 60,098,863 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1760,089,692 - 60,098,850 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11758,939,430 - 58,948,415 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01759,023,178 - 59,032,132 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01759,749,960 - 59,759,005 (+)NCBIUU_Cfam_GSD_1.0
Fcgr1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505821,085,119 - 21,114,589 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936580115,450 - 145,785 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936580115,552 - 144,970 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FCGR1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl499,233,611 - 99,242,586 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1499,233,632 - 99,242,531 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24108,773,630 - 108,782,529 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 18
Low 36 2 60
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: XM_008019202   ⟹   XP_008017393
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603813,502,010 - 13,510,802 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008019203   ⟹   XP_008017394
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603813,502,010 - 13,510,802 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008017393 (Get FASTA)   NCBI Sequence Viewer  
  XP_008017394 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000014157.1
Reference Protein Sequences
RefSeq Acc Id: XP_008017394   ⟸   XM_008019203
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RZW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008017393   ⟸   XM_008019202
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RZW8 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018139 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016236.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
NCBI Gene LOC103247163 ENTREZGENE
PANTHER HIGH AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR I-RELATED UniProtKB/TrEMBL
  IMMUNOGLOBULIN FC RECEPTOR UniProtKB/TrEMBL
Pfam Ig_2 UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
  PF00047 UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A0D9RZW8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 FCGR1A  Fc fragment of IgG receptor Ia  LOC103247163  high affinity immunoglobulin gamma Fc receptor I  Symbol and/or name change 5135510 APPROVED