GDPD2 (glycerophosphodiester phosphodiesterase domain containing 2) - Rat Genome Database

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Gene: GDPD2 (glycerophosphodiester phosphodiesterase domain containing 2) Chlorocebus sabaeus
Analyze
Symbol: GDPD2
Name: glycerophosphodiester phosphodiesterase domain containing 2
RGD ID: 18571892
Description: ENCODES a protein that exhibits glycerophosphodiester phosphodiesterase activity (inferred); phosphoric diester hydrolase activity (inferred); INVOLVED IN actin filament organization (ortholog); positive regulation of osteoblast differentiation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN actin filament (inferred); lamellipodium (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glycerophosphoinositol inositolphosphodiesterase GDPD2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X60,268,125 - 60,279,128 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX60,268,485 - 60,279,796 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660652,112,282 - 2,122,672 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GDPD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X60,268,125 - 60,279,128 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX60,268,485 - 60,279,796 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660652,112,282 - 2,122,672 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
GDPD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X70,423,314 - 70,433,381 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX70,423,031 - 70,433,390 (+)EnsemblGRCh38hg38GRCh38
GRCh37X69,643,164 - 69,653,231 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X69,559,716 - 69,569,956 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X69,426,011 - 69,436,251NCBI
CeleraX69,996,203 - 70,006,563 (+)NCBICelera
Cytogenetic MapXq13.1NCBI
HuRefX63,464,255 - 63,474,606 (+)NCBIHuRef
CHM1_1X69,536,774 - 69,547,134 (+)NCBICHM1_1
T2T-CHM13v2.0X68,856,634 - 68,866,693 (+)NCBIT2T-CHM13v2.0
Gdpd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X99,773,442 - 99,782,507 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX99,773,479 - 99,782,501 (+)EnsemblGRCm39 Ensembl
GRCm38X100,729,836 - 100,738,901 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX100,729,873 - 100,738,895 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X97,925,186 - 97,934,238 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X96,932,659 - 96,941,612 (+)NCBIMGSCv36mm8
CeleraX87,654,592 - 87,663,644 (+)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX43.72NCBI
Gdpd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X69,866,395 - 69,875,419 (+)NCBIGRCr8
mRatBN7.2X65,826,273 - 65,835,361 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX65,826,574 - 65,835,361 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX67,309,957 - 67,318,744 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X70,810,351 - 70,819,138 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X68,371,257 - 68,380,044 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X70,563,381 - 70,572,295 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX70,563,570 - 70,572,295 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X71,435,008 - 71,443,913 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X88,744,485 - 88,753,272 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX66,185,410 - 66,194,198 (+)NCBICelera
Cytogenetic MapXq22NCBI
Gdpd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554759,972,664 - 9,985,939 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554759,972,797 - 9,983,145 (+)NCBIChiLan1.0ChiLan1.0
GDPD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X70,098,795 - 70,110,408 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X70,102,402 - 70,114,010 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X59,689,983 - 59,701,585 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X69,748,999 - 69,759,364 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX69,748,999 - 69,759,364 (+)Ensemblpanpan1.1panPan2
GDPD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X54,865,674 - 54,875,536 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX54,865,818 - 54,875,530 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX45,692,130 - 45,701,974 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X55,832,324 - 55,842,171 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX55,832,309 - 55,905,961 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X53,801,237 - 53,811,081 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X55,132,316 - 55,142,163 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X55,059,253 - 55,069,100 (+)NCBIUU_Cfam_GSD_1.0
Gdpd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X47,286,423 - 47,297,886 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367621,048,586 - 1,060,153 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367621,048,597 - 1,060,085 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GDPD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX56,449,425 - 56,460,392 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X56,449,430 - 56,460,399 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X63,644,264 - 63,655,190 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Gdpd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624903388,866 - 400,607 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624903388,935 - 399,793 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 11 16
Low 9 12 44
Below cutoff 16 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000009701   ⟹   ENSCSAP00000007813
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 EnsemblX60,268,485 - 60,279,796 (+)Ensembl
RefSeq Acc Id: XM_007991981   ⟹   XP_007990172
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X60,268,129 - 60,279,128 (+)NCBI
Vero_WHO_p1.0NW_0236660652,112,282 - 2,122,672 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007991984   ⟹   XP_007990175
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X60,268,130 - 60,279,128 (+)NCBI
Vero_WHO_p1.0NW_0236660652,112,284 - 2,122,672 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007991985   ⟹   XP_007990176
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X60,268,128 - 60,279,128 (+)NCBI
Vero_WHO_p1.0NW_0236660652,112,282 - 2,122,672 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007990172 (Get FASTA)   NCBI Sequence Viewer  
  XP_007990175 (Get FASTA)   NCBI Sequence Viewer  
  XP_007990176 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007813.1
Reference Protein Sequences
RefSeq Acc Id: XP_007990176   ⟸   XM_007991985
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RGS4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007990172   ⟸   XM_007991981
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RGS4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007990175   ⟸   XM_007991984
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RGS4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000007813   ⟸   ENSCSAT00000009701


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011616 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009701.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.190 UniProtKB/TrEMBL
InterPro GP_PDE_dom UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/TrEMBL
KEGG Report csab:103232133 UniProtKB/TrEMBL
NCBI Gene GDPD2 ENTREZGENE
PANTHER GLYCEROPHOSPHOINOSITOL INOSITOLPHOSPHODIESTERASE GDPD2 UniProtKB/TrEMBL
  GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE UniProtKB/TrEMBL
Pfam GDPD UniProtKB/TrEMBL
  GDPD_2 UniProtKB/TrEMBL
PROSITE GP_PDE UniProtKB/TrEMBL
Superfamily-SCOP SSF51695 UniProtKB/TrEMBL
UniProt A0A0D9RGS4 ENTREZGENE, UniProtKB/TrEMBL