LRRC17 (leucine rich repeat containing 17) - Rat Genome Database

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Gene: LRRC17 (leucine rich repeat containing 17) Chlorocebus sabaeus
Analyze
Symbol: LRRC17
Name: leucine rich repeat containing 17
RGD ID: 18568351
Description: INVOLVED IN bone marrow development (ortholog); negative regulation of osteoclast differentiation (ortholog); osteoblast differentiation (ortholog); ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine-rich repeat-containing protein 17
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12171,977,522 - 72,009,069 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2171,976,823 - 72,011,023 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604231,987,968 - 32,019,915 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LRRC17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12171,977,522 - 72,009,069 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2171,976,823 - 72,011,023 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604231,987,968 - 32,019,915 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LRRC17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387102,913,000 - 102,945,111 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7102,913,000 - 102,945,111 (+)EnsemblGRCh38hg38GRCh38
GRCh377102,553,447 - 102,585,558 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367102,340,688 - 102,372,632 (+)NCBINCBI36Build 36hg18NCBI36
Build 347102,147,402 - 102,179,347NCBI
Celera797,360,514 - 97,393,405 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef796,915,676 - 96,948,566 (+)NCBIHuRef
CHM1_17102,486,708 - 102,518,921 (+)NCBICHM1_1
T2T-CHM13v2.07104,227,406 - 104,260,198 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27101,913,710 - 101,945,924 (+)NCBI
Lrrc17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39521,748,525 - 21,780,909 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl521,748,557 - 21,780,902 (+)EnsemblGRCm39 Ensembl
GRCm38521,543,527 - 21,575,911 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl521,543,559 - 21,575,904 (+)EnsemblGRCm38mm10GRCm38
MGSCv37521,049,345 - 21,081,729 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera518,509,757 - 18,543,716 (+)NCBICelera
Cytogenetic Map5A3NCBI
cM Map59.89NCBI
Lrrc17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8414,393,632 - 14,424,048 (-)NCBIGRCr8
mRatBN7.2413,501,428 - 13,531,845 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl413,501,436 - 13,531,845 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx418,641,283 - 18,671,645 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0414,450,513 - 14,480,848 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0412,826,929 - 12,857,287 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0410,108,184 - 10,138,652 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl410,108,192 - 10,138,652 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0410,109,700 - 10,139,147 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.448,961,466 - 8,992,108 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera49,078,209 - 9,108,449 (-)NCBICelera
Cytogenetic Map4q11NCBI
Lrrc17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554108,094,926 - 8,128,623 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554108,093,621 - 8,128,623 (+)NCBIChiLan1.0ChiLan1.0
LRRC17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26139,752,299 - 139,785,835 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17188,022,279 - 188,055,805 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0794,884,624 - 94,917,576 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17107,734,929 - 107,767,951 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7107,756,505 - 107,767,445 (+)Ensemblpanpan1.1panPan2
LRRC17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11817,103,834 - 17,132,653 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1817,104,184 - 17,118,012 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1816,762,338 - 16,791,491 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01817,422,204 - 17,451,505 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1817,422,192 - 17,436,069 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11817,174,730 - 17,203,888 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01817,113,460 - 17,142,617 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01817,382,332 - 17,411,488 (-)NCBIUU_Cfam_GSD_1.0
Lrrc17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511859,268,874 - 59,299,505 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647920,392,523 - 20,423,281 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647920,392,485 - 20,423,209 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRC17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9103,062,667 - 103,094,350 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19103,062,653 - 103,099,886 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29113,456,551 - 113,472,428 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Lrrc17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473926,265,804 - 26,299,136 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473926,266,863 - 26,299,009 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 36 16 60
Below cutoff 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000009849   ⟹   ENSCSAP00000007958
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2171,976,823 - 72,011,023 (+)Ensembl
RefSeq Acc Id: XM_007982426   ⟹   XP_007980617
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12171,977,522 - 72,009,069 (+)NCBI
Vero_WHO_p1.0NW_02366604231,987,968 - 32,019,915 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007982427   ⟹   XP_007980618
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12171,977,522 - 72,007,681 (+)NCBI
Vero_WHO_p1.0NW_02366604231,990,649 - 32,019,915 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038004347   ⟹   XP_037860275
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604231,987,968 - 32,009,952 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007980617 (Get FASTA)   NCBI Sequence Viewer  
  XP_007980618 (Get FASTA)   NCBI Sequence Viewer  
  XP_037860275 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007958.1
Reference Protein Sequences
RefSeq Acc Id: XP_007980617   ⟸   XM_007982426
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RH69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007980618   ⟸   XM_007982427
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000007958   ⟸   ENSCSAT00000009849
RefSeq Acc Id: XP_037860275   ⟸   XM_038004347
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RH69 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011758 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009849.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103226676 UniProtKB/TrEMBL
NCBI Gene LRRC17 ENTREZGENE
PANTHER ANTIGEN BSP, PUTATIVE-RELATED UniProtKB/TrEMBL
  CHAOPTIN-RELATED UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
PRINTS LEURICHRPT UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A0D9RH69 ENTREZGENE, UniProtKB/TrEMBL