FNDC8 (fibronectin type III domain containing 8)

Gene: FNDC8 (fibronectin type III domain containing 8) Chlorocebus sabaeus

Analyze

Symbol:

FNDC8

Name:

fibronectin type III domain containing 8

RGD ID:

18563327

Description:

ASSOCIATED WITH genetic disease (ortholog); hereditary breast ovarian cancer syndrome (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

fibronectin type III domain-containing protein 8

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	28,624,441 - 28,633,723 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	28,624,735 - 28,633,537 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666075	1,353,489 - 1,363,002 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

hereditary breast ovarian cancer syndrome (ISO)

Neurodevelopmental Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

nucleus (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

FNDC8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	28,624,441 - 28,633,723 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	28,624,735 - 28,633,537 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666075	1,353,489 - 1,363,002 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

FNDC8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	35,121,615 - 35,130,732 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	35,121,615 - 35,130,732 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	33,448,634 - 33,457,751 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	30,472,744 - 30,481,864 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	17	30,358,824 - 30,367,943 (+)	NCBI		Celera
Cytogenetic Map	17	q12	NCBI
HuRef	17	29,633,318 - 29,642,432 (+)	NCBI		HuRef
CHM1_1	17	33,512,993 - 33,522,110 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	36,069,529 - 36,078,645 (+)	NCBI		T2T-CHM13v2.0

Fndc8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	82,782,971 - 82,791,563 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	82,782,950 - 82,791,627 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	82,892,145 - 82,900,737 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	82,892,124 - 82,900,801 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	82,705,647 - 82,714,239 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	82,708,319 - 82,716,996 (+)	NCBI		MGSCv36	mm8
Celera	11	92,511,195 - 92,519,852 (+)	NCBI		Celera
Cytogenetic Map	11	C	NCBI
cM Map	11	50.3	NCBI

Fndc8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	68,323,500 - 68,331,638 (+)	NCBI		GRCr8
mRatBN7.2	10	67,825,952 - 67,834,090 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	67,825,952 - 67,834,090 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	72,445,992 - 72,454,130 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	71,951,373 - 71,959,511 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	67,415,477 - 67,423,603 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	70,242,852 - 70,250,990 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	70,242,874 - 70,250,934 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	69,874,015 - 69,882,153 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	71,109,016 - 71,117,154 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	71,122,706 - 71,129,721 (+)	NCBI
Celera	10	66,770,188 - 66,778,326 (+)	NCBI		Celera
Cytogenetic Map	10	q26	NCBI

Fndc8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955481	9,812,156 - 9,819,865 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955481	9,812,402 - 9,820,070 (+)	NCBI	ChiLan1.0	ChiLan1.0

FNDC8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	29,334,255 - 29,346,016 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	31,215,227 - 31,226,962 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	21,655,487 - 21,665,633 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	21,947,380 - 21,956,499 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	21,947,380 - 21,956,499 (-)	Ensembl	panpan1.1		panPan2

FNDC8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	38,232,116 - 38,240,791 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	38,232,117 - 38,240,791 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	37,456,092 - 37,464,981 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	39,044,045 - 39,052,943 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	39,044,046 - 39,052,888 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	37,827,609 - 37,836,517 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	38,113,127 - 38,122,029 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	38,200,661 - 38,209,559 (-)	NCBI		UU_Cfam_GSD_1.0

Fndc8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	37,232,976 - 37,240,130 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936538	111,241 - 117,961 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936538	110,569 - 117,961 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FNDC8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	40,045,094 - 40,052,597 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	40,045,721 - 40,052,637 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	41,556,921 - 41,563,844 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Fndc8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624875	2,989,359 - 2,996,183 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624875	2,989,290 - 2,996,406 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium
Low		16	6
Below cutoff	15	4	46

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008011043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008011044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000004348 ⟹ ENSCSAP00000002603

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	16	28,624,735 - 28,633,537 (+)	Ensembl

RefSeq Acc Id:

XM_008011044 ⟹ XP_008009235

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	16	28,624,441 - 28,633,723 (+)	NCBI
Vero_WHO_p1.0	NW_023666075	1,353,489 - 1,363,002 (-)	NCBI

Sequence:

show sequence

GGGGCCCAAGGGCTCATGCAGTCTGTTCCTTGGTTTTACCCCTCTCATGATGCTGCTTCTCAGT
CACACTGGCCCTTGGTCTGGCCAGCCACATAGCTAGCGGGACAGCAGTGACCTCAAATCAAGGG
GGGAGGCCGGCCCGTAATTGTTACTCTCTGTGAAGATTATGAAGTCAGCTCGTTGCACTTGCAT
CCTGCCCAGACTAAAGGTGGGCCACTGCCACCACAGTTTCTCTCTGCTTCTGGTCAGCTGGGTT
GTCCCGCACAGTGACGGCTGTCATCCCAAACAAACCAGATGGCATCAGAGGCACTCCATCAAGT
GGGAGATGGGGAGGAGGCTGTACTGAAGAAAGAAAACTTCAACATGATGAATGCCCTCGACCAA
CTGCCAAAACCCTTTCCAAACCCCAAGTCTATGAACCGGACCGTCACTACCAAAGGACTCCCAC
TTTCCTCAAAGGGCAATTTGGTCAACTTCTTGAAGGATGATACCATCAACCTACCGAAGCCAAT
GCCAGTGGATGATTCAGATTGCAGCTCTGATGATACCAGCATCTCTGCCTTCTCATCCACCTTG
CTGAACCCCATCAAATTAGCTGTGACCCAGCCCAACAGCAGCTTCTTTGCAGGGATGCTGGAGG
GGGAGCTGAACAAACTCAGCTTCTCCCCGATGGCCAAGAATACAGAAAAGGAGGACCTGGCCCT
CGGCCCCTGCCCATGCCCATCTAAGTGCCAAATGGCCACGAGGGGCCTGCTGGACCTTGACAGC
CCTGAGCTGGAGACAGAAACCTCCTCAATGGACTCGGAATCTTCTGTGGTTGTGGACCTGCCGG
ACACCCCCTTCATCTTCGAGCACACTGTCAGCAATTCCACAGCTGTGATTTCCTGGACCTACGC
CTTGGGCAAGCAGCCGGTCAGTTTCTACCAGGTCCTGTTGCAGGAGGCGGCCGAGACACAGGAG
AATGAGTTGCCCAAGGCAAAGAATCGTCCATGGATCTTCAACAAGATCTTGGGCACCACTGTCA
AGCTGATGGAGCTGAAGCCTAACACATGTTACTGCCTCACTGTCCGTGCAGCCAACACAGCTGG
GGTGGGGAAGTGGTGCAAGCCCTACAAATTTGCAACCCTGGCCACTGACTTCAGCAGCTTTCCT
GAGAACAACCCCATCCAGATCACCGTGCGGCGCAAGGAACCCCAGCGAAAGATCGTGTCCATCA
GGCTGGAGGAGATGCGGAGGCTGGAGGATCTGGAATACCTATTTCCCTATTAACAGGGAGGGCC
CCAGGACACCCCTCACCAACTTTCAGCTTTGGCCCCGGGCCCTTAGGAACCAGAACTGTGAGAC
TTACCGTACCACCAGCACCATGCGGGCCCAAGGGCCTGGCAGAGTGGTATGGGAACCCCACCCC
TGGGCTGGGGCCAGGTCCCTCATTAAAGAACTGCAGGCCATCTAGCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008009235	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000002603.1

RefSeq Acc Id:	XP_008009235 ⟸ XM_008011044
- UniProtKB:	A0A0D9R1W4 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000002603 ⟸ ENSCSAT00000004348

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000006312	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000004348.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	FN3_dom	UniProtKB/TrEMBL
	FN3_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
NCBI Gene	FNDC8	ENTREZGENE
PANTHER	FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 8	UniProtKB/TrEMBL
	FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 8	UniProtKB/TrEMBL
Pfam	fn3	UniProtKB/TrEMBL
PROSITE	FN3	UniProtKB/TrEMBL
SMART	FN3	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49265	UniProtKB/TrEMBL
UniProt	A0A0D9R1W4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar