AP4M1 (adaptor related protein complex 4 subunit mu 1) - Rat Genome Database

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Gene: AP4M1 (adaptor related protein complex 4 subunit mu 1) Chlorocebus sabaeus
Analyze
Symbol: AP4M1
Name: adaptor related protein complex 4 subunit mu 1
RGD ID: 18561922
Description: ENCODES a protein that exhibits protein domain specific binding (inferred); INVOLVED IN protein localization to basolateral plasma membrane (ortholog); ASSOCIATED WITH Alazami-Yuan Syndrome (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN trans-Golgi network (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: adaptor related protein complex 4 mu 1 subunit; AP-4 complex subunit mu-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,971,007 - 12,976,914 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,971,297 - 12,976,779 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,296,018 - 3,301,894 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
AP4M1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,971,007 - 12,976,914 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,971,297 - 12,976,779 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,296,018 - 3,301,894 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
AP4M1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,100,794 - 100,109,039 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,100,858 - 100,110,345 (+)EnsemblGRCh38hg38GRCh38
GRCh37799,699,266 - 99,706,662 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,537,066 - 99,542,739 (+)NCBINCBI36Build 36hg18NCBI36
Build 34799,343,830 - 99,349,453NCBI
Celera794,433,789 - 94,439,462 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,334,781 - 94,340,455 (+)NCBIHuRef
CHM1_1799,629,287 - 99,634,960 (+)NCBICHM1_1
T2T-CHM13v2.07101,340,729 - 101,348,885 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,059,249 - 99,064,921 (+)NCBI
Ap4m1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395138,170,283 - 138,178,691 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5138,170,264 - 138,178,691 (+)EnsemblGRCm39 Ensembl
GRCm385138,172,021 - 138,180,429 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5138,172,002 - 138,180,429 (+)EnsemblGRCm38mm10GRCm38
MGSCv375138,613,249 - 138,619,915 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,401,809 - 138,408,471 (+)NCBIMGSCv36mm8
Celera5135,151,353 - 135,157,995 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.98NCBI
Ap4m1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81222,163,474 - 22,171,734 (+)NCBIGRCr8
mRatBN7.21217,049,766 - 17,055,954 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1217,049,777 - 17,058,026 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1217,873,224 - 17,879,102 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,496,968 - 18,502,846 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01217,550,374 - 17,556,252 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,314,222 - 19,320,339 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,314,251 - 19,320,142 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,371,852 - 21,377,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41217,614,882 - 17,620,773 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11217,604,001 - 17,610,295 (+)NCBI
Celera1218,980,013 - 18,985,904 (+)NCBICelera
Cytogenetic Map12q11NCBI
Ap4m1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573759,222 - 763,222 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955573759,222 - 763,222 (-)NCBIChiLan1.0ChiLan1.0
AP4M1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,020,512 - 118,028,432 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,285,144 - 166,293,064 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,137,085 - 92,142,756 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17105,570,205 - 105,575,971 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7105,570,205 - 105,575,971 (+)Ensemblpanpan1.1panPan2
AP4M1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.169,488,496 - 9,492,703 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,486,372 - 9,492,243 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.069,425,495 - 9,429,591 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl69,423,773 - 9,429,399 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.169,274,807 - 9,278,909 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.069,255,130 - 9,259,226 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.069,434,718 - 9,438,823 (-)NCBIUU_Cfam_GSD_1.0
Ap4m1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,784,566 - 133,790,213 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543246,335 - 254,975 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543246,335 - 250,278 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AP4M1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,013,747 - 8,017,700 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,013,701 - 8,017,701 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Ap4m1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,883,828 - 16,887,685 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,883,725 - 16,887,678 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in AP4M1
101 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000015944   ⟹   ENSCSAP00000013869
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2812,971,297 - 12,976,779 (-)Ensembl
RefSeq Acc Id: XM_008018589   ⟹   XP_008016780
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12812,971,007 - 12,976,740 (-)NCBI
Vero_WHO_p1.0NW_0236660703,296,123 - 3,301,894 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008018590   ⟹   XP_008016781
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12812,971,007 - 12,976,914 (-)NCBI
Vero_WHO_p1.0NW_0236660703,296,018 - 3,301,894 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037990380   ⟹   XP_037846308
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660703,296,124 - 3,301,894 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008016780 (Get FASTA)   NCBI Sequence Viewer  
  XP_008016781 (Get FASTA)   NCBI Sequence Viewer  
  XP_037846308 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000013869
  ENSCSAP00000013869.1
RefSeq Acc Id: XP_008016781   ⟸   XM_008018590
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RZ30 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008016780   ⟸   XM_008018589
- Peptide Label: isoform X1
Ensembl Acc Id: ENSCSAP00000013869   ⟸   ENSCSAT00000015944
RefSeq Acc Id: XP_037846308   ⟸   XM_037990380
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017849 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015944.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.450.60 UniProtKB/TrEMBL
  Mu homology domain, subdomain B UniProtKB/TrEMBL
InterPro Adaptor_comp_med_subunit UniProtKB/TrEMBL
  AP2_Mu_C_sf UniProtKB/TrEMBL
  AP_mu_sigma_su UniProtKB/TrEMBL
  Clathrin_mu UniProtKB/TrEMBL
  Clathrin_mu_CS UniProtKB/TrEMBL
  Longin-like_dom_sf UniProtKB/TrEMBL
  MHD UniProtKB/TrEMBL
NCBI Gene AP4M1 ENTREZGENE
PANTHER AP COMPLEX SUBUNIT MU UniProtKB/TrEMBL
Pfam Adap_comp_sub UniProtKB/TrEMBL
  Clat_adaptor_s UniProtKB/TrEMBL
PIRSF Clathrin_mu UniProtKB/TrEMBL
PRINTS CLATHRINADPT UniProtKB/TrEMBL
PROSITE CLAT_ADAPTOR_M_2 UniProtKB/TrEMBL
  MHD UniProtKB/TrEMBL
Superfamily-SCOP SSF49447 UniProtKB/TrEMBL
  SSF64356 UniProtKB/TrEMBL
UniProt A0A0D9RZ30 ENTREZGENE, UniProtKB/TrEMBL