ERP27 (endoplasmic reticulum protein 27) - Rat Genome Database

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Gene: ERP27 (endoplasmic reticulum protein 27) Chlorocebus sabaeus
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Symbol: ERP27
Name: endoplasmic reticulum protein 27
RGD ID: 18561238
Description: ENCODES a protein that exhibits protein disulfide isomerase activity (inferred); INVOLVED IN protein folding (inferred); response to endoplasmic reticulum stress (inferred); ASSOCIATED WITH autosomal dominant intellectual developmental disorder 6 (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: endoplasmic reticulum resident protein 27
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11114,810,071 - 14,836,427 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1114,811,473 - 14,826,652 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606920,472,804 - 20,500,419 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ERP27
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11114,810,071 - 14,836,427 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1114,811,473 - 14,826,652 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606920,472,804 - 20,500,419 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ERP27
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381214,914,039 - 14,938,537 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1214,914,039 - 14,938,537 (-)EnsemblGRCh38hg38GRCh38
GRCh371215,066,973 - 15,091,471 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361214,958,245 - 14,982,722 (-)NCBINCBI36Build 36hg18NCBI36
Celera1220,211,961 - 20,236,462 (-)NCBICelera
Cytogenetic Map12p12.3NCBI
HuRef1214,836,429 - 14,860,831 (-)NCBIHuRef
CHM1_11215,033,060 - 15,057,554 (-)NCBICHM1_1
T2T-CHM13v2.01214,791,381 - 14,815,874 (-)NCBIT2T-CHM13v2.0
Erp27
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396136,884,312 - 136,899,465 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6136,884,309 - 136,899,178 (-)EnsemblGRCm39 Ensembl
GRCm386136,907,314 - 136,922,461 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6136,907,311 - 136,922,180 (-)EnsemblGRCm38mm10GRCm38
MGSCv376136,855,908 - 136,870,701 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366136,871,583 - 136,886,376 (-)NCBIMGSCv36mm8
Celera6139,946,928 - 139,962,190 (-)NCBICelera
Cytogenetic Map6G1NCBI
cM Map666.72NCBI
Erp27
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84171,535,845 - 171,552,848 (-)NCBIGRCr8
mRatBN7.24169,804,656 - 169,821,660 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4169,804,658 - 169,821,660 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4176,099,696 - 176,116,814 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04171,881,113 - 171,898,110 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04170,505,365 - 170,522,479 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04170,893,946 - 170,912,629 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4170,893,946 - 170,912,629 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04235,150,711 - 235,169,448 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44173,948,853 - 173,966,545 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4158,387,137 - 158,404,147 (-)NCBICelera
Cytogenetic Map4q43NCBI
Erp27
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541311,650,991 - 11,669,968 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541311,650,920 - 11,670,127 (-)NCBIChiLan1.0ChiLan1.0
ERP27
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21020,362,399 - 20,386,939 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11220,359,160 - 20,383,700 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01214,916,781 - 14,940,991 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11215,313,546 - 15,337,989 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1215,313,546 - 15,337,989 (-)Ensemblpanpan1.1panPan2
ERP27
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12731,682,586 - 31,702,959 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2731,682,896 - 31,702,773 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2714,746,020 - 14,766,367 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02731,989,217 - 32,009,577 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2731,989,378 - 32,009,383 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12731,878,591 - 31,898,917 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02731,837,047 - 31,857,394 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02714,478,223 - 14,498,576 (-)NCBIUU_Cfam_GSD_1.0
Erp27
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494592,822,735 - 92,840,148 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365872,550,604 - 2,567,150 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365872,550,649 - 2,567,213 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERP27
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl557,599,802 - 57,626,628 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1557,599,497 - 57,626,638 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2560,988,503 - 61,015,590 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Erp27
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475223,091,620 - 23,107,923 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475223,091,620 - 23,108,890 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 25 20 19
Below cutoff 11 34

Sequence


RefSeq Acc Id: ENSCSAT00000006427   ⟹   ENSCSAP00000004631
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1114,811,473 - 14,826,652 (-)Ensembl
RefSeq Acc Id: XM_007967757   ⟹   XP_007965948
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11114,810,071 - 14,836,427 (-)NCBI
Vero_WHO_p1.0NW_02366606920,472,804 - 20,500,419 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007967758   ⟹   XP_007965949
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11114,811,335 - 14,827,332 (-)NCBI
Vero_WHO_p1.0NW_02366606920,483,278 - 20,500,419 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007965948 (Get FASTA)   NCBI Sequence Viewer  
  XP_007965949 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004631.1
RefSeq Acc Id: XP_007965948   ⟸   XM_007967757
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007965949   ⟸   XM_007967758
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R7P2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000004631   ⟸   ENSCSAT00000006427


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008373 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006427.1 UniProtKB/TrEMBL
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
InterPro Thioredoxin-like_sf UniProtKB/TrEMBL
NCBI Gene ERP27 ENTREZGENE
PANTHER ENDOPLASMIC RETICULUM RESIDENT PROTEIN 27 UniProtKB/TrEMBL
  PROTEIN DISULFIDE ISOMERASE UniProtKB/TrEMBL
Pfam Thioredoxin_6 UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
UniProt A0A0D9R7P2 ENTREZGENE, UniProtKB/TrEMBL