MRPS18A (mitochondrial ribosomal protein S18A)

Gene: MRPS18A (mitochondrial ribosomal protein S18A) Chlorocebus sabaeus

Analyze

Symbol:

MRPS18A

Name:

mitochondrial ribosomal protein S18A

RGD ID:

18560646

Description:

ENCODES a protein that exhibits small ribosomal subunit rRNA binding (inferred); structural constituent of ribosome (inferred); INVOLVED IN mitochondrial translation (inferred); translation (inferred); ASSOCIATED WITH genetic disease (ortholog); infantile Refsum disease (ortholog); Zellweger syndrome (ortholog); FOUND IN mitochondrial large ribosomal subunit (inferred); mitochondrial small ribosomal subunit (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

28S ribosomal protein S18a, mitochondrial; 39S ribosomal protein S18a, mitochondrial

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	28,480,669 - 28,497,354 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	28,480,660 - 28,500,706 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	43,720,626 - 43,737,567 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

infantile Refsum disease (ISO)

Zellweger syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mitochondrial translation (IEA)

translation (IEA)

Cellular Component

mitochondrial large ribosomal subunit (IEA)

mitochondrial small ribosomal subunit (IEA)

mitochondrion (IEA)

ribonucleoprotein complex (IEA)

ribosome (IEA)

Molecular Function

small ribosomal subunit rRNA binding (IEA)

structural constituent of ribosome (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

MRPS18A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	28,480,669 - 28,497,354 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	28,480,660 - 28,500,706 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	43,720,626 - 43,737,567 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

MRPS18A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	43,671,202 - 43,687,791 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	43,671,202 - 43,687,791 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	43,638,939 - 43,655,528 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	43,747,020 - 43,763,506 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	43,747,019 - 43,763,506	NCBI
Celera	6	45,190,561 - 45,207,176 (-)	NCBI		Celera
Cytogenetic Map	6	p21.1	NCBI
HuRef	6	43,357,975 - 43,367,902 (-)	NCBI		HuRef
CHM1_1	6	43,641,931 - 43,658,546 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	43,499,929 - 43,516,525 (-)	NCBI		T2T-CHM13v2.0

Mrps18a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	46,421,930 - 46,439,834 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	46,421,912 - 46,439,836 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	46,111,004 - 46,128,908 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	46,110,986 - 46,128,910 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	46,247,953 - 46,265,857 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	45,574,585 - 45,592,489 (+)	NCBI		MGSCv36	mm8
Celera	17	49,542,531 - 49,560,014 (+)	NCBI		Celera
Cytogenetic Map	17	C	NCBI
cM Map	17	22.86	NCBI

Mrps18a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	22,350,887 - 22,367,380 (-)	NCBI		GRCr8
mRatBN7.2	9	14,853,322 - 14,869,819 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	14,853,291 - 14,869,835 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	23,437,742 - 23,454,215 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	28,500,162 - 28,516,632 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	26,801,172 - 26,817,647 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	17,238,354 - 17,254,845 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	17,238,385 - 17,254,949 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	16,133,557 - 16,150,048 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	10,419,079 - 10,435,570 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	10,416,402 - 10,432,892 (-)	NCBI
Celera	9	12,600,343 - 12,616,808 (-)	NCBI		Celera
Cytogenetic Map	9	q12	NCBI

Mrps18a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	9,448,612 - 9,462,874 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	9,448,612 - 9,462,874 (-)	NCBI	ChiLan1.0	ChiLan1.0

MRPS18A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	58,169,474 - 58,186,105 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	54,039,267 - 54,055,852 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	43,261,336 - 43,278,022 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	44,550,865 - 44,567,552 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	44,550,865 - 44,567,552 (-)	Ensembl	panpan1.1		panPan2

MRPS18A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	12,106,104 - 12,122,922 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	12,096,568 - 12,122,997 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	12,132,339 - 12,149,157 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	12,589,873 - 12,606,689 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	12,589,880 - 12,606,649 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	12,114,923 - 12,131,738 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	12,201,923 - 12,218,736 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	12,295,445 - 12,312,253 (-)	NCBI		UU_Cfam_GSD_1.0

Mrps18a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	47,601,522 - 47,624,805 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	16,335,421 - 16,351,363 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	16,335,396 - 16,351,661 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MRPS18A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	38,635,967 - 38,657,253 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	38,641,755 - 38,657,472 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	44,224,282 - 44,232,879 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Mrps18a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	16,016,680 - 16,031,368 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	16,016,670 - 16,031,368 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	19		15
Low	17	20	45
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007972433	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007972434	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000010220 ⟹ ENSCSAP00000008315

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	17	28,480,660 - 28,500,706 (+)	Ensembl

RefSeq Acc Id:

XM_007972433 ⟹ XP_007970624

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	17	28,480,669 - 28,496,943 (+)	NCBI
Vero_WHO_p1.0	NW_023666044	43,720,770 - 43,737,476 (-)	NCBI

Sequence:

show sequence

AAATGGATAAGAGATCAGGGTAGGTTTCTCAAGATGGCGGCCTTCAAGGGTTTGGTGTCGGCCT
ATGGGGGGCTTCTCCGTGGGCTCCTAGCGGGCCCGGCAGCGACCAGCTGGTCTCGGCTTCCAGC
TCGCGGGTTCAGGGAAGTGGTGGAGATCCAAGAAGGGAAGACAACTATAATTGAAGGCCGTCTC
ACAGCGACTCCCAAGGGCAGTCCAAATCCTCCTAACCCCTCTGGCCAGTGCCCCATCTGCCGTT
GGAACCTGAAGCACAAGTATAACTATGACGATGTTCTGCTGCTTAGCCAGTTCATCCGGCCTCA
TGGAGGCATGCTGCCACGAAAGATCACAGGCCTATGCCAGGAAGAACACCGCAAGATTGAGGAG
TGTGTGAAGATGGCCCACCGAGCAGGTAGAAGGTCCTGGGGACCAAGAGGGGCAGAGGGCCGCA
GGCGCTCTCTCCCTACCCGGCTGCCCCATGTTTCAGCCCCTCCTGAAAGAAAAGAGAATATCCA
GAGTGTTAATTATACTCCCCATCCAATGCCCACCTCCCCACTCCCTTGGGCTTTCCCTCTGGCC
CCCTCAGAGCTGCAGAGGGAGCTGCAAAGACTATCCCATCTTCCCCCCACTCAGGTCTATTACC
AAATCACAGGCCTCGGCTTCCTGAAGGAGTTGTTCCGAAAAGCAAACCTCAACTCAACCGGTAC
CTGACGCGCTGGGCTCCTGGCTCTGTCAAGCCCATCTA

hide sequence

RefSeq Acc Id:

XM_007972434 ⟹ XP_007970625

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	17	28,480,671 - 28,497,354 (+)	NCBI
Vero_WHO_p1.0	NW_023666044	43,720,626 - 43,737,567 (-)	NCBI

Sequence:

show sequence

ATGGATAAGAGATCAGGGTAGGTTTCTCAAGATGGCGGCCTTCAAGGGTTTGGTGTCGGCCTAT
GGGGGGCTTCTCCGTGGGCTCCTAGCGGGCCCGGCAGCGACCAGCTGGTCTCGGCTTCCAGCTC
GCGGGTTCAGGGAAGTGGTGGAGATCCAAGAAGGGAAGACAACTATAATTGAAGGCCGTCTCAC
AGCGACTCCCAAGGGCAGTCCAAATCCTCCTAACCCCTCTGGCCAGTGCCCCATCTGCCGTTGG
AACCTGAAGCACAAGTATAACTATGACGATGTTCTGCTGCTTAGCCAGTTCATCCGGCCTCATG
GAGGCATGCTGCCACGAAAGATCACAGGCCTATGCCAGGAAGAACACCGCAAGATTGAGGAGTG
TGTGAAGATGGCCCACCGAGCAGGTCTATTACCAAATCACAGGCCTCGGCTTCCTGAAGGAGTT
GTTCCGAAAAGCAAACCTCAACTCAACCGGTACCTGACGCGCTGGGCTCCTGGCTCTGTCAAGC
CCATCTACAAAAAAGGCCCCCGCTGGAACAAGGTGTGCATGCCCGTGGGGTCACCCCTCCTGAG
GGACAATGTCTGCTACTCAAGAACACCTTGGAAGCTGTATCACTGACAGAGAGCAGGGCTTCCA
GAGTTCCTCCTGCACCTGTGATGGGGAGTAAGAGGCACACTCATAAGCCCTCGGCCACAACTAT
ACTCCAGATCACGATGGCCTGGCCCCTTCGACATGGATGGACAGGGGACAGTGGGACTAACTTT
AGTACCTTTGGCCTGTGCAGTAGCAATGCTGGGAGCTAAAGGCAGGCAGGGCAGTTGGGTCCCT
TGCCAGGTGCTGTGGGGCTTGGGCCATGCTCAGTGCTGGGGACAGGAGTTTTTCCCAATACAGT
GTCATAAACATTCAGTTGTGGGCTCGTAGGCTTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007970624	(Get FASTA)	NCBI Sequence Viewer
	XP_007970625	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000008315
	ENSCSAP00000008315.1

RefSeq Acc Id:	XP_007970624 ⟸ XM_007972433
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_007970625 ⟸ XM_007972434
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9RI76 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000008315 ⟸ ENSCSAT00000010220

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000012127	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000010220.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.640.10	UniProtKB/TrEMBL
InterPro	Ribosomal_S18	UniProtKB/TrEMBL
	Ribosomal_S18_sf	UniProtKB/TrEMBL
NCBI Gene	MRPS18A	ENTREZGENE
PANTHER	39S RIBOSOMAL PROTEIN S18A, MITOCHONDRIAL	UniProtKB/TrEMBL
	PTHR13479	UniProtKB/TrEMBL
Pfam	Ribosomal_S18	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46911	UniProtKB/TrEMBL
UniProt	A0A0D9RI76	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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