RTTN (rotatin) - Rat Genome Database

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Gene: RTTN (rotatin) Chlorocebus sabaeus
Analyze
Symbol: RTTN
Name: rotatin
RGD ID: 18553594
Description: INVOLVED IN determination of left/right symmetry (ortholog); ASSOCIATED WITH chromosome 18q deletion syndrome (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN centriole (inferred); centrosome (inferred); ciliary basal body (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1189,574,647 - 9,770,940 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl189,575,159 - 9,772,596 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606016,043,053 - 16,239,698 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
RTTN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1189,574,647 - 9,770,940 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl189,575,159 - 9,772,596 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606016,043,053 - 16,239,698 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RTTN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381870,003,031 - 70,205,687 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1870,003,031 - 70,205,726 (-)EnsemblGRCh38hg38GRCh38
GRCh371867,670,267 - 67,872,923 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361865,822,020 - 66,023,942 (-)NCBINCBI36Build 36hg18NCBI36
Build 341865,822,020 - 66,023,942NCBI
Celera1864,518,916 - 64,720,330 (-)NCBICelera
Cytogenetic Map18q22.2NCBI
HuRef1864,389,979 - 64,591,919 (-)NCBIHuRef
CHM1_11867,666,254 - 67,868,184 (-)NCBICHM1_1
T2T-CHM13v2.01870,220,081 - 70,422,743 (-)NCBIT2T-CHM13v2.0
Rttn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391888,989,860 - 89,149,140 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1888,989,914 - 89,149,140 (+)EnsemblGRCm39 Ensembl
GRCm381888,971,736 - 89,131,014 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1888,971,790 - 89,131,016 (+)EnsemblGRCm38mm10GRCm38
MGSCv371889,141,182 - 89,300,406 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361889,105,983 - 89,265,207 (+)NCBIMGSCv36mm8
Celera1890,700,317 - 90,859,209 (+)NCBICelera
Cytogenetic Map18E4NCBI
cM Map1858.93NCBI
Rttn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81884,495,813 - 84,673,079 (+)NCBIGRCr8
mRatBN7.21882,220,999 - 82,398,334 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1882,221,050 - 82,398,333 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1884,284,095 - 84,453,846 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01884,957,328 - 85,127,073 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01882,825,473 - 83,001,026 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01886,071,884 - 86,247,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1886,071,662 - 86,247,486 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01885,110,453 - 85,286,009 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41885,830,884 - 86,012,604 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11885,950,678 - 86,085,700 (+)NCBI
Celera1880,771,824 - 80,948,867 (+)NCBICelera
Cytogenetic Map18q13NCBI
Rttn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540253,600,985 - 53,753,459 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540253,600,985 - 53,753,218 (-)NCBIChiLan1.0ChiLan1.0
RTTN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21787,533,160 - 87,735,673 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11873,222,172 - 73,428,292 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01863,381,953 - 63,584,937 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11866,674,250 - 66,874,390 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1866,674,597 - 66,874,104 (-)Ensemblpanpan1.1panPan2
RTTN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.118,180,831 - 8,326,947 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl18,180,888 - 8,323,346 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha19,191,081 - 9,333,849 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.018,010,620 - 8,153,335 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl18,010,620 - 8,153,597 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.118,032,050 - 8,174,811 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.017,992,299 - 8,135,078 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.018,202,269 - 8,345,164 (+)NCBIUU_Cfam_GSD_1.0
Rttn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494421,997,733 - 22,069,016 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049369641,369 - 71,142 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RTTN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1152,689,504 - 152,833,946 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11152,688,305 - 152,833,969 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21169,083,952 - 169,146,612 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Rttn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480611,058,880 - 11,266,289 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480611,058,138 - 11,266,639 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 10
Low 36 20 50
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000016316   ⟹   ENSCSAP00000014235
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl189,575,159 - 9,772,596 (+)Ensembl
RefSeq Acc Id: XM_008013806   ⟹   XP_008011997
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1189,574,650 - 9,770,940 (+)NCBI
Vero_WHO_p1.0NW_02366606016,043,053 - 16,239,698 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037987993   ⟹   XP_037843921
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606016,043,053 - 16,239,698 (-)NCBI
RefSeq Acc Id: XM_037987994   ⟹   XP_037843922
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606016,043,053 - 16,239,698 (-)NCBI
RefSeq Acc Id: XM_037987995   ⟹   XP_037843923
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606016,043,053 - 16,237,398 (-)NCBI
RefSeq Acc Id: XM_037987996   ⟹   XP_037843924
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606016,059,820 - 16,239,698 (-)NCBI
RefSeq Acc Id: XM_037987997   ⟹   XP_037843925
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606016,067,625 - 16,239,698 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008011997   ⟸   XM_008013806
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S046 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000014235   ⟸   ENSCSAT00000016316
RefSeq Acc Id: XP_037843922   ⟸   XM_037987994
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S046 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843921   ⟸   XM_037987993
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S046 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843923   ⟸   XM_037987995
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S046 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843924   ⟸   XM_037987996
- Peptide Label: isoform X5
- UniProtKB: A0A0D9S046 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843925   ⟸   XM_037987997
- Peptide Label: isoform X6
- UniProtKB: A0A0D9S046 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018219 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016316.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Rotatin UniProtKB/TrEMBL
  Rotatin_N UniProtKB/TrEMBL
KEGG Report csab:103244116 UniProtKB/TrEMBL
NCBI Gene RTTN ENTREZGENE
PANTHER PTHR31691 UniProtKB/TrEMBL
  ROTATIN UniProtKB/TrEMBL
Pfam RTTN_N UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A0D9S046 ENTREZGENE, UniProtKB/TrEMBL