MED9 (mediator complex subunit 9) - Rat Genome Database

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Gene: MED9 (mediator complex subunit 9) Chlorocebus sabaeus
Analyze
Symbol: MED9
Name: mediator complex subunit 9
RGD ID: 18553068
Description: ENCODES a protein that exhibits transcription coregulator activity (inferred); INVOLVED IN regulation of transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH autistic disorder (ortholog); Birt-Hogg-Dube syndrome (ortholog); common variable immunodeficiency 2 (ortholog); FOUND IN core mediator complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mediator of RNA polymerase II transcription subunit 9
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11616,513,144 - 16,527,880 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1616,512,898 - 16,527,875 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660594,385,612 - 4,400,663 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MED9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11616,513,144 - 16,527,880 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1616,512,898 - 16,527,875 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660594,385,612 - 4,400,663 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
MED9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381717,477,000 - 17,493,221 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1717,476,994 - 17,493,221 (+)EnsemblGRCh38hg38GRCh38
GRCh371717,380,314 - 17,396,535 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361717,321,025 - 17,337,259 (+)NCBINCBI36Build 36hg18NCBI36
Build 341717,321,024 - 17,337,259NCBI
Celera1718,319,685 - 18,335,921 (+)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1717,132,586 - 17,148,822 (+)NCBIHuRef
CHM1_11717,388,947 - 17,405,182 (+)NCBICHM1_1
T2T-CHM13v2.01717,423,576 - 17,439,799 (+)NCBIT2T-CHM13v2.0
Med9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391159,839,040 - 59,854,132 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1159,839,032 - 59,853,031 (+)EnsemblGRCm39 Ensembl
GRCm381159,948,214 - 59,963,306 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1159,948,206 - 59,962,205 (+)EnsemblGRCm38mm10GRCm38
MGSCv371159,761,716 - 59,776,808 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361160,484,794 - 60,499,886 (+)NCBIMGSCv36mm8
MGSCv361159,764,409 - 59,779,501 (+)NCBIMGSCv36mm8
Cytogenetic Map11B1.3NCBI
cM Map1137.81NCBI
Med9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81045,250,229 - 45,264,988 (+)NCBIGRCr8
mRatBN7.21044,750,667 - 44,765,464 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1044,750,698 - 44,765,464 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1049,451,029 - 49,465,671 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01048,941,392 - 48,956,034 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01044,445,001 - 44,459,643 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01046,314,639 - 46,329,374 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1046,314,375 - 46,329,373 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01046,071,310 - 46,086,081 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,274,791 - 46,290,414 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1044,011,092 - 44,025,801 (+)NCBICelera
Cytogenetic Map10q22NCBI
Med9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955577454,715 - 470,152 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955577455,879 - 470,126 (-)NCBIChiLan1.0ChiLan1.0
MED9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21951,992,797 - 52,009,001 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11756,704,794 - 56,720,996 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01733,802,916 - 33,819,107 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11738,749,397 - 38,765,618 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1738,749,397 - 38,765,618 (-)Ensemblpanpan1.1panPan2
MED9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1541,967,951 - 41,982,354 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl541,967,651 - 41,982,349 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha542,106,027 - 42,120,418 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0542,074,169 - 42,088,586 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl542,074,178 - 42,088,594 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1542,041,185 - 42,055,568 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0541,988,575 - 42,002,980 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0542,180,485 - 42,194,883 (-)NCBIUU_Cfam_GSD_1.0
Med9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560261,747,281 - 61,783,426 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367411,106,741 - 1,120,053 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367411,083,822 - 1,119,967 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MED9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1260,906,718 - 60,933,944 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11260,925,161 - 60,933,999 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21263,124,513 - 63,133,351 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Med9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248493,920,268 - 3,934,777 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248493,920,046 - 3,934,748 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 32
Low 20 28
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008010525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000006499   ⟹   ENSCSAP00000004702
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1616,512,898 - 16,527,875 (+)Ensembl
RefSeq Acc Id: XM_008010525   ⟹   XP_008008716
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11616,513,144 - 16,527,880 (+)NCBI
Vero_WHO_p1.0NW_0236660594,385,612 - 4,400,663 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008008716 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004702
  ENSCSAP00000004702.1
Reference Protein Sequences
RefSeq Acc Id: XP_008008716   ⟸   XM_008010525
- UniProtKB: A0A0D9R7W3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000004702   ⟸   ENSCSAT00000006499


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008446 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006499.1 UniProtKB/TrEMBL
InterPro Med7/Med21-like UniProtKB/TrEMBL
  Med9 UniProtKB/TrEMBL
  MED9_metazoa UniProtKB/TrEMBL
KEGG Report csab:103242473 UniProtKB/TrEMBL
NCBI Gene MED9 ENTREZGENE
PANTHER MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 9 UniProtKB/TrEMBL
  PTHR20844 UniProtKB/TrEMBL
Pfam Med9 UniProtKB/TrEMBL
Superfamily-SCOP SSF140718 UniProtKB/TrEMBL
UniProt A0A0D9R7W3 ENTREZGENE, UniProtKB/TrEMBL