MLF2 (myeloid leukemia factor 2) - Rat Genome Database

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Gene: MLF2 (myeloid leukemia factor 2) Chlorocebus sabaeus
Analyze
Symbol: MLF2
Name: myeloid leukemia factor 2
RGD ID: 18550505
Description: INVOLVED IN regulation of DNA-templated transcription (inferred); ASSOCIATED WITH genetic disease (ortholog); Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); lymphoproliferative syndrome 2 (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,784,182 - 6,789,289 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl116,783,437 - 6,789,622 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660631,434,575 - 1,439,713 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MLF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,784,182 - 6,789,289 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl116,783,437 - 6,789,622 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660631,434,575 - 1,439,713 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
MLF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,747,996 - 6,753,141 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,747,996 - 6,767,475 (-)EnsemblGRCh38hg38GRCh38
GRCh37126,857,162 - 6,862,307 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,727,423 - 6,732,530 (-)NCBINCBI36Build 36hg18NCBI36
Build 34126,727,423 - 6,732,530NCBI
Celera128,474,453 - 8,479,931 (-)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef126,710,655 - 6,716,132 (-)NCBIHuRef
CHM1_1126,856,136 - 6,861,614 (-)NCBICHM1_1
T2T-CHM13v2.0126,757,561 - 6,762,706 (-)NCBIT2T-CHM13v2.0
Mlf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,908,351 - 124,913,112 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,908,349 - 124,914,201 (+)EnsemblGRCm39 Ensembl
GRCm386124,931,388 - 124,936,149 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,931,386 - 124,937,238 (+)EnsemblGRCm38mm10GRCm38
MGSCv376124,881,406 - 124,886,167 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,897,095 - 124,901,763 (+)NCBIMGSCv36mm8
Celera6126,608,333 - 126,612,493 (+)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.17NCBI
Mlf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,425,542 - 159,430,584 (+)NCBIGRCr8
mRatBN7.24157,739,651 - 157,744,325 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,728,756 - 157,744,317 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,968,402 - 163,972,577 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,751,323 - 159,755,498 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,386,739 - 158,390,940 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,452,578 - 157,457,254 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,452,607 - 157,457,249 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,470,409 - 224,475,074 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44161,058,932 - 161,063,117 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14161,303,469 - 161,308,046 (+)NCBI
Celera4146,477,454 - 146,481,643 (+)NCBICelera
Cytogenetic Map4q42NCBI
Mlf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,359,936 - 4,364,284 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,359,936 - 4,364,284 (-)NCBIChiLan1.0ChiLan1.0
MLF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,310,633 - 12,329,810 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,307,804 - 12,326,816 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0126,879,347 - 6,898,785 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,793,045 - 6,798,715 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,793,045 - 6,798,715 (-)Ensemblpanpan1.1panPan2
MLF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,284,495 - 38,289,125 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,284,534 - 38,288,851 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,327,554 - 8,332,188 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,637,114 - 38,641,744 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,637,085 - 38,641,742 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,511,057 - 38,515,690 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,552,306 - 38,556,940 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0277,806,782 - 7,811,412 (-)NCBIUU_Cfam_GSD_1.0
Mlf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,385,876 - 102,402,704 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367091,053,408 - 1,070,253 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MLF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,951,722 - 63,957,141 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,951,660 - 63,957,154 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,386,119 - 66,391,590 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Mlf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,437,136 - 3,441,455 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248603,437,286 - 3,441,332 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 10 60
Low 10
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000008421   ⟹   ENSCSAP00000006569
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl116,783,437 - 6,789,622 (-)Ensembl
RefSeq Acc Id: XM_007967403   ⟹   XP_007965594
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1116,784,182 - 6,789,289 (-)NCBI
Vero_WHO_p1.0NW_0236660631,434,575 - 1,439,713 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007965594 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000006569
  ENSCSAP00000006569.1
RefSeq Acc Id: XP_007965594   ⟸   XM_007967403
- UniProtKB: A0A0D9RD80 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000006569   ⟸   ENSCSAT00000008421


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010338 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008421.1 UniProtKB/TrEMBL
InterPro Myeloid_leukemia_factor UniProtKB/TrEMBL
KEGG Report csab:103218473 UniProtKB/TrEMBL
NCBI Gene MLF2 ENTREZGENE
PANTHER MYELOID LEUKEMIA FACTOR 2 UniProtKB/TrEMBL
  PTHR13105 UniProtKB/TrEMBL
Pfam Mlf1IP UniProtKB/TrEMBL
UniProt A0A0D9RD80 ENTREZGENE, UniProtKB/TrEMBL