STX5 (syntaxin 5) - Rat Genome Database

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Gene: STX5 (syntaxin 5) Chlorocebus sabaeus
Analyze
Symbol: STX5
Name: syntaxin 5
RGD ID: 18533457
Description: ENCODES a protein that exhibits SNAP receptor activity (inferred); SNARE binding (inferred); INVOLVED IN endoplasmic reticulum to Golgi vesicle-mediated transport (ortholog); retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (ortholog); vesicle fusion with Golgi apparatus (ortholog); ASSOCIATED WITH Congenital Disorder of Glycosylation Type IIaa (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN Golgi membrane (ortholog); SNARE complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: syntaxin-5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,071,099 - 11,094,880 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,071,118 - 11,096,189 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,413,656 - 108,438,404 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
STX5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,071,099 - 11,094,880 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,071,118 - 11,096,189 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,413,656 - 108,438,404 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
STX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,806,860 - 62,832,051 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,806,860 - 62,832,051 (-)EnsemblGRCh38hg38GRCh38
GRCh371162,574,332 - 62,599,523 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,330,945 - 62,356,136 (-)NCBINCBI36Build 36hg18NCBI36
Build 341162,330,945 - 62,356,116NCBI
Celera1151,132,647 - 51,133,735 (-)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,903,359 - 58,928,592 (-)NCBIHuRef
CHM1_11162,457,414 - 62,482,605 (-)NCBICHM1_1
T2T-CHM13v2.01162,796,253 - 62,821,448 (-)NCBIT2T-CHM13v2.0
Stx5a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,718,788 - 8,733,006 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl198,718,777 - 8,733,433 (+)EnsemblGRCm39 Ensembl
GRCm38198,741,424 - 8,755,642 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,741,413 - 8,756,069 (+)EnsemblGRCm38mm10GRCm38
MGSCv37198,815,914 - 8,830,132 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36198,808,865 - 8,822,687 (+)NCBIMGSCv36mm8
Celera198,501,497 - 8,515,650 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.45NCBI
Stx5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,066,532 - 215,082,685 (+)NCBIGRCr8
mRatBN7.21205,637,401 - 205,653,563 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1205,637,413 - 205,653,563 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,043,349 - 214,060,740 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,080,959 - 221,097,118 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01213,773,666 - 213,789,822 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,939,497 - 224,955,658 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,939,497 - 224,955,657 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01231,876,955 - 231,893,830 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,409,653 - 211,426,725 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11211,568,082 - 211,585,155 (+)NCBI
Celera1203,150,296 - 203,166,494 (+)NCBICelera
Cytogenetic Map1q43NCBI
Stx5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599414,392 - 438,581 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955599414,338 - 438,581 (+)NCBIChiLan1.0ChiLan1.0
STX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2964,031,964 - 64,057,121 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11165,074,656 - 65,099,815 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01158,162,269 - 58,187,427 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,516,348 - 61,541,509 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,516,348 - 61,541,509 (-)Ensemblpanpan1.1panPan2
STX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,862,432 - 53,883,091 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,862,541 - 53,882,536 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,468,474 - 52,489,127 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01854,914,883 - 54,935,546 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1854,914,989 - 54,935,543 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,011,528 - 54,032,175 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,585,960 - 53,606,622 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,382,237 - 54,402,893 (+)NCBIUU_Cfam_GSD_1.0
Stx5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,348,660 - 10,373,817 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936581462,969 - 487,578 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936581462,417 - 487,563 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl28,937,778 - 8,968,932 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.128,937,705 - 8,968,513 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,283,018 - 8,313,748 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Stx5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,270,624 - 1,286,060 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249261,270,624 - 1,286,439 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 33
Low 20 27
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000004789   ⟹   ENSCSAP00000003033
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl111,071,118 - 11,096,189 (+)Ensembl
RefSeq Acc Id: XM_007995128   ⟹   XP_007993319
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1111,071,099 - 11,094,880 (+)NCBI
Vero_WHO_p1.0NW_023666038108,413,656 - 108,438,404 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007995138   ⟹   XP_007993329
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1111,071,308 - 11,094,880 (+)NCBI
Vero_WHO_p1.0NW_023666038108,413,887 - 108,438,404 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007995145   ⟹   XP_007993336
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1111,071,100 - 11,094,880 (+)NCBI
Vero_WHO_p1.0NW_023666038108,413,680 - 108,438,374 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037999183   ⟹   XP_037855111
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038108,413,707 - 108,429,926 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007993319 (Get FASTA)   NCBI Sequence Viewer  
  XP_007993329 (Get FASTA)   NCBI Sequence Viewer  
  XP_007993336 (Get FASTA)   NCBI Sequence Viewer  
  XP_037855111 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000003033
  ENSCSAP00000003033.1
Reference Protein Sequences
RefSeq Acc Id: XP_007993319   ⟸   XM_007995128
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R344 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007993336   ⟸   XM_007995145
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007993329   ⟸   XM_007995138
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R344 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000003033   ⟸   ENSCSAT00000004789
RefSeq Acc Id: XP_037855111   ⟸   XM_037999183
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000006748 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000004789.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.70 UniProtKB/TrEMBL
InterPro SNARE UniProtKB/TrEMBL
  Syntaxin UniProtKB/TrEMBL
  Syntaxin-5_N UniProtKB/TrEMBL
  Syntaxin/epimorphin_CS UniProtKB/TrEMBL
  T_SNARE_dom UniProtKB/TrEMBL
KEGG Report csab:103233839 UniProtKB/TrEMBL
NCBI Gene STX5 ENTREZGENE
PANTHER PTHR19957 UniProtKB/TrEMBL
  SYNTAXIN-5 UniProtKB/TrEMBL
Pfam SNARE UniProtKB/TrEMBL
  Syntaxin-5_N UniProtKB/TrEMBL
PROSITE SYNTAXIN UniProtKB/TrEMBL
  T_SNARE UniProtKB/TrEMBL
SMART t_SNARE UniProtKB/TrEMBL
Superfamily-SCOP SSF47661 UniProtKB/TrEMBL
UniProt A0A0D9R344 ENTREZGENE, UniProtKB/TrEMBL