C2CD4B (C2 calcium dependent domain containing 4B) - Rat Genome Database

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Gene: C2CD4B (C2 calcium dependent domain containing 4B) Chlorocebus sabaeus
Analyze
Symbol: C2CD4B
Name: C2 calcium dependent domain containing 4B
RGD ID: 18526932
Description: INVOLVED IN positive regulation of acute inflammatory response (inferred); regulation of cell adhesion (inferred); regulation of vascular permeability involved in acute inflammatory response (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C2 calcium-dependent domain-containing protein 4B
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12621,359,297 - 21,361,910 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2621,360,448 - 21,361,542 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048120,024,085 - 120,025,916 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
C2CD4B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12621,359,297 - 21,361,910 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2621,360,448 - 21,361,542 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048120,024,085 - 120,025,916 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
C2CD4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381562,163,535 - 62,165,285 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1562,163,535 - 62,165,285 (-)EnsemblGRCh38hg38GRCh38
GRCh371562,455,734 - 62,457,484 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361560,243,029 - 60,244,774 (-)NCBINCBI36Build 36hg18NCBI36
Celera1539,344,987 - 39,346,711 (-)NCBICelera
Cytogenetic Map15q22.2NCBI
HuRef1539,278,319 - 39,280,064 (-)NCBIHuRef
CHM1_11562,575,256 - 62,577,001 (-)NCBICHM1_1
T2T-CHM13v2.01559,967,560 - 59,969,310 (-)NCBIT2T-CHM13v2.0
C2cd4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39967,623,506 - 67,668,215 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl967,666,719 - 67,668,212 (+)EnsemblGRCm39 Ensembl
GRCm38967,716,224 - 67,760,933 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl967,759,437 - 67,760,930 (+)EnsemblGRCm38mm10GRCm38
MGSCv37967,607,244 - 67,608,740 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36967,557,740 - 67,560,097 (+)NCBIMGSCv36mm8
Celera964,984,639 - 65,001,904 (+)NCBICelera
Cytogenetic Map9CNCBI
cM Map936.72NCBI
C2cd4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8877,254,327 - 77,277,620 (+)NCBIGRCr8
mRatBN7.2868,372,793 - 68,396,477 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl868,384,847 - 68,396,328 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0873,555,414 - 73,580,848 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl873,593,310 - 73,594,332 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0877,922,752 - 77,924,242 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4872,110,481 - 72,111,976 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera873,325,140 - 73,350,574 (-)NCBICelera
Cytogenetic Map8q24NCBI
C2CD4B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21651,425,264 - 51,431,870 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11555,601,272 - 55,607,878 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01541,113,568 - 41,125,725 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11559,423,128 - 59,424,148 (-)NCBIpanpan1.1PanPan1.1panPan2
LOC100688626
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13026,865,346 - 26,875,141 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3026,781,205 - 26,789,608 (-)NCBIDog10K_Boxer_Tasha
C2cd4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640105,091,377 - 105,093,016 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493647122,939,454 - 22,941,728 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C2CD4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11109,824,467 - 109,827,631 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21121,255,210 - 121,257,404 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 16 16
Low 20 12 40
Below cutoff 7 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008016375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000019828   ⟹   ENSCSAP00000019233
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2621,360,448 - 21,361,542 (+)Ensembl
RefSeq Acc Id: XM_008016375   ⟹   XP_008014566
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12621,359,297 - 21,361,910 (+)NCBI
Vero_WHO_p1.0NW_023666048120,024,085 - 120,025,916 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008014566 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000019233
  ENSCSAP00000019233.1
Reference Protein Sequences
RefSeq Acc Id: XP_008014566   ⟸   XM_008016375
- UniProtKB: A0A0D9SEE4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000019233   ⟸   ENSCSAT00000019828


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000019738 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000019828.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_Ca-dependent_4 UniProtKB/TrEMBL
  C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
KEGG Report csab:103245522 UniProtKB/TrEMBL
NCBI Gene C2CD4B ENTREZGENE
PANTHER C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4B UniProtKB/TrEMBL
  PTHR47226 UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A0D9SEE4 ENTREZGENE, UniProtKB/TrEMBL