LOC103218923 (guided entry of tail-anchored proteins factor 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: LOC103218923 (guided entry of tail-anchored proteins factor 1) Chlorocebus sabaeus
Analyze
Symbol: LOC103218923 (Ensembl: SH3BGR)
Name: guided entry of tail-anchored proteins factor 1 (Ensembl:SH3 domain binding glutamate rich protein)
RGD ID: 18517593
Description: ENCODES a protein that exhibits protein-membrane adaptor activity (inferred); INVOLVED IN establishment of protein localization to membrane (inferred); tail-anchored membrane protein insertion into ER membrane (inferred); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: GET1; SH3 domain-binding glutamic acid-rich protein; SH3BGR; tail-anchored protein insertion receptor WRB; tryptophan rich basic protein; WRB
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1283,395,130 - 83,458,485 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl283,325,899 - 83,342,185 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
ChlSab1.1 Ensembl283,401,732 - 83,455,416 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605411,185,960 - 11,318,122 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC103218923
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1283,395,130 - 83,458,485 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl283,325,899 - 83,342,185 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
ChlSab1.1 Ensembl283,401,732 - 83,455,416 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605411,185,960 - 11,318,122 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SH3BGR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382139,445,865 - 39,515,506 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2139,445,855 - 39,515,506 (+)EnsemblGRCh38hg38GRCh38
GRCh372140,817,791 - 40,887,433 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362139,739,667 - 39,809,303 (+)NCBINCBI36Build 36hg18NCBI36
Build 342139,745,649 - 39,809,302NCBI
Celera2126,015,495 - 26,085,127 (+)NCBICelera
Cytogenetic Map21q22.2NCBI
HuRef2126,286,675 - 26,357,208 (+)NCBIHuRef
CHM1_12140,378,935 - 40,448,548 (+)NCBICHM1_1
T2T-CHM13v2.02137,830,488 - 37,900,126 (+)NCBIT2T-CHM13v2.0
Sh3bgr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391696,001,670 - 96,030,133 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1696,001,650 - 96,030,135 (+)EnsemblGRCm39 Ensembl
GRCm381696,200,470 - 96,228,933 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1696,200,450 - 96,228,935 (+)EnsemblGRCm38mm10GRCm38
MGSCv371696,422,077 - 96,450,540 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361696,305,614 - 96,329,470 (+)NCBIMGSCv36mm8
Celera1697,274,391 - 97,301,969 (+)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1656.86NCBI
Sh3bgr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81148,973,033 - 48,997,328 (+)NCBIGRCr8
mRatBN7.21135,503,663 - 35,527,853 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,503,725 - 35,527,853 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1144,160,745 - 44,184,889 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01136,832,126 - 36,856,270 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01135,978,116 - 36,002,181 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01136,555,354 - 36,579,537 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1136,555,416 - 36,579,535 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01140,086,045 - 40,110,164 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41136,511,326 - 36,535,444 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1132,944,120 - 32,968,430 (-)NCBICelera
Cytogenetic Map11q11NCBI
Sh3bgr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540738,225,718 - 38,258,125 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540738,225,827 - 38,265,792 (+)NCBIChiLan1.0ChiLan1.0
SH3BGR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22235,543,418 - 35,613,655 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12130,399,318 - 30,469,759 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02125,798,888 - 25,869,102 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12139,142,685 - 39,205,414 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2139,142,685 - 39,205,402 (+)Ensemblpanpan1.1panPan2
LOC119867070
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha3133,495,810 - 33,551,676 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03133,729,949 - 33,785,714 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3133,729,957 - 33,785,659 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13133,601,873 - 33,657,248 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03133,606,662 - 33,662,604 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03134,098,099 - 34,153,975 (+)NCBIUU_Cfam_GSD_1.0
LOC101973230
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497133,628,715 - 33,767,203 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365003,703,846 - 3,751,278 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_0049365003,814,904 - 3,831,935 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365003,700,620 - 3,751,532 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH3BGR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13203,046,553 - 203,108,634 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113203,046,575 - 203,108,638 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213213,286,145 - 213,348,193 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sh3bgr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474524,538,069 - 24,574,036 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 31 31
Low 5 19 29
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007968241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007968246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007968247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007968368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037984825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000006372   ⟹   ENSCSAP00000004576
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl283,401,732 - 83,455,416 (+)Ensembl
RefSeq Acc Id: XM_007968241   ⟹   XP_007966432
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1283,401,143 - 83,458,485 (+)NCBI
Vero_WHO_p1.0NW_02366605411,261,376 - 11,318,122 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007968246   ⟹   XP_007966437
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1283,395,130 - 83,458,485 (+)NCBI
Vero_WHO_p1.0NW_02366605411,254,905 - 11,318,122 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007968368   ⟹   XP_007966559
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,185,977 - 11,202,734 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037984813   ⟹   XP_037840741
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,185,960 - 11,318,122 (+)NCBI
RefSeq Acc Id: XM_037984814   ⟹   XP_037840742
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,186,350 - 11,318,122 (+)NCBI
RefSeq Acc Id: XM_037984815   ⟹   XP_037840743
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,186,350 - 11,318,122 (+)NCBI
RefSeq Acc Id: XM_037984816   ⟹   XP_037840744
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,186,204 - 11,318,122 (+)NCBI
RefSeq Acc Id: XM_037984817   ⟹   XP_037840745
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,186,160 - 11,318,122 (+)NCBI
RefSeq Acc Id: XM_037984818   ⟹   XP_037840746
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,186,169 - 11,318,122 (+)NCBI
RefSeq Acc Id: XM_037984819   ⟹   XP_037840747
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,186,193 - 11,318,122 (+)NCBI
RefSeq Acc Id: XM_037984820   ⟹   XP_037840748
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,185,977 - 11,199,979 (+)NCBI
RefSeq Acc Id: XM_037984821   ⟹   XP_037840749
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,254,996 - 11,318,122 (+)NCBI
RefSeq Acc Id: XM_037984822   ⟹   XP_037840750
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,253,853 - 11,318,122 (+)NCBI
RefSeq Acc Id: XM_037984823   ⟹   XP_037840751
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,186,017 - 11,202,637 (+)NCBI
RefSeq Acc Id: XM_037984824   ⟹   XP_037840752
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,186,143 - 11,202,637 (+)NCBI
RefSeq Acc Id: XM_037984825   ⟹   XP_037840753
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605411,186,017 - 11,202,637 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007966437   ⟸   XM_007968246
- Peptide Label: isoform X7
RefSeq Acc Id: XP_007966432   ⟸   XM_007968241
- Peptide Label: isoform X5
- UniProtKB: A0A0D9R7I7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000004576   ⟸   ENSCSAT00000006372
RefSeq Acc Id: XP_037840741   ⟸   XM_037984813
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007966559   ⟸   XM_007968368
- Peptide Label: isoform X6
- UniProtKB: A0A0D9R7K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037840748   ⟸   XM_037984820
- Peptide Label: isoform X8
RefSeq Acc Id: XP_037840751   ⟸   XM_037984823
- Peptide Label: isoform X10
RefSeq Acc Id: XP_037840753   ⟸   XM_037984825
- Peptide Label: isoform X10
RefSeq Acc Id: XP_037840752   ⟸   XM_037984824
- Peptide Label: isoform X10
RefSeq Acc Id: XP_037840745   ⟸   XM_037984817
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037840746   ⟸   XM_037984818
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037840747   ⟸   XM_037984819
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037840744   ⟸   XM_037984816
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037840742   ⟸   XM_037984814
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037840743   ⟸   XM_037984815
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037840750   ⟸   XM_037984822
- Peptide Label: isoform X9
RefSeq Acc Id: XP_037840749   ⟸   XM_037984821
- Peptide Label: isoform X9


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008320 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSCSAG00000008355 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006372.1 UniProtKB/TrEMBL
  ENSCSAT00000006385.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.660 UniProtKB/TrEMBL
  Glutaredoxin UniProtKB/TrEMBL
InterPro Get1 UniProtKB/TrEMBL
  Glut_rich_SH3-bd UniProtKB/TrEMBL
  Helix_hairpin_bin_sf UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
NCBI Gene SH3BGR ENTREZGENE
PANTHER GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1 UniProtKB/TrEMBL
  SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH PROTEIN UniProtKB/TrEMBL
  SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN UniProtKB/TrEMBL
  TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB UniProtKB/TrEMBL
Pfam CHD5 UniProtKB/TrEMBL
  SH3BGR UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
UniProt A0A0D9R7I7 ENTREZGENE, UniProtKB/TrEMBL
  A0A0D9R7K2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 LOC103218923  guided entry of tail-anchored proteins factor 1  SH3BGR  SH3 domain binding glutamate rich protein  Symbol and/or name change 5135510 APPROVED
2020-12-03 SH3BGR  SH3 domain binding glutamate rich protein  GET1  guided entry of tail-anchored proteins factor 1  Data merged from RGD:18779166 737654 PROVISIONAL