CHRNB2 (cholinergic receptor nicotinic beta 2 subunit)

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Gene: CHRNB2 (cholinergic receptor nicotinic beta 2 subunit) Chlorocebus sabaeus

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Symbol:

CHRNB2

Name:

cholinergic receptor nicotinic beta 2 subunit

RGD ID:

18515087

Description:

ENCODES a protein that exhibits acetylcholine binding (ortholog); acetylcholine-gated monoatomic cation-selective channel activity (ortholog); heterocyclic compound binding (ortholog); INVOLVED IN acetylcholine receptor signaling pathway (ortholog); action potential (ortholog); associative learning (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; ASSOCIATED WITH Abnormal Reflexes (ortholog); Alzheimer's disease (ortholog); anxiety disorder (ortholog); FOUND IN acetylcholine-gated channel complex (ortholog); cholinergic synapse (ortholog); dopaminergic synapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

neuronal acetylcholine receptor subunit beta-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	9,245,803 - 9,255,430 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	9,247,231 - 9,253,795 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	8,581,863 - 8,595,204 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Abnormal Reflexes (ISO)

Alzheimer's disease (ISO)

anxiety disorder (ISO)

attention deficit hyperactivity disorder (ISO)

autism spectrum disorder (ISO)

autistic disorder (ISO)

autosomal dominant nocturnal frontal lobe epilepsy (ISO)

autosomal dominant nocturnal frontal lobe epilepsy 1 (ISO)

autosomal dominant nocturnal frontal lobe epilepsy 3 (ISO)

benign familial infantile seizures 6 (ISO)

Charcot-Marie-Tooth disease type 2 (ISO)

dyschromatosis symmetrica hereditaria (ISO)

epilepsy (ISO)

frontal lobe epilepsy (ISO)

gastrointestinal stromal tumor (ISO)

Generalized Epilepsy (ISO)

genetic disease (ISO)

Hypothermia (ISO)

immunodeficiency 42 (ISO)

Inflammation (ISO)

intellectual disability (ISO)

MHC class II deficiency (ISO)

Nerve Degeneration (ISO)

parathyroid carcinoma (ISO)

partial motor epilepsy (ISO)

severe congenital neutropenia 3 (ISO)

severe congenital neutropenia 5 (ISO)

sleep disorder (ISO)

sudden infant death syndrome (ISO)

withdrawal disorder (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acetylcholine receptor signaling pathway (ISO)

action potential (ISO)

associative learning (ISO)

B cell activation (ISO)

B cell proliferation (ISO)

behavioral response to nicotine (IEA,ISO)

calcium ion transport (ISO)

central nervous system neuron axonogenesis (ISO)

central nervous system projection neuron axonogenesis (ISO)

chemical synaptic transmission (IEA)

cognition (IEA)

conditioned taste aversion (ISO)

dopamine secretion (ISO)

establishment of localization in cell (ISO)

excitatory postsynaptic potential (IEA)

lateral geniculate nucleus development (ISO)

learning (IEA,ISO)

locomotory behavior (ISO)

membrane depolarization (ISO)

memory (IEA,ISO)

monoatomic ion transmembrane transport (IEA)

negative regulation of neuronal action potential (ISO)

nervous system process (IEA)

neuronal action potential (ISO)

optic nerve morphogenesis (ISO)

positive regulation of B cell proliferation (ISO)

positive regulation of dopamine secretion (ISO)

positive regulation of synaptic transmission, dopaminergic (ISO)

presynaptic modulation of chemical synaptic transmission (ISO)

regulation of circadian sleep/wake cycle, non-REM sleep (ISO)

regulation of circadian sleep/wake cycle, REM sleep (ISO)

regulation of dendrite morphogenesis (ISO)

regulation of dopamine metabolic process (ISO)

regulation of dopamine secretion (ISO)

regulation of membrane potential (IEA,ISO)

regulation of postsynaptic membrane potential (IEA)

regulation of synapse assembly (ISO)

regulation of synaptic transmission, dopaminergic (ISO)

response to acetylcholine (ISO)

response to cocaine (ISO)

response to ethanol (ISO)

response to hypoxia (IEA,ISO)

response to nicotine (IEA,ISO)

sensory perception of pain (ISO)

sensory perception of sound (ISO)

signal transduction (IEA)

smooth muscle contraction (ISO)

social behavior (ISO)

synaptic transmission involved in micturition (ISO)

synaptic transmission, cholinergic (IEA,ISO)

vestibulocochlear nerve development (ISO)

visual learning (IEA,ISO)

visual perception (ISO)

Cellular Component

acetylcholine-gated channel complex (IEA,ISO)

cholinergic synapse (ISO)

dopaminergic synapse (ISO)

external side of plasma membrane (ISO)

neuron projection (IEA)

plasma membrane (IEA)

plasma membrane raft (ISO)

postsynaptic membrane (IEA)

postsynaptic specialization membrane (ISO)

presynapse (ISO)

presynaptic membrane (ISO)

protein-containing complex (ISO)

synapse (IEA)

Molecular Function

acetylcholine binding (IEA,ISO)

acetylcholine receptor activity (IEA)

acetylcholine-gated monoatomic cation-selective channel activity (IEA,ISO)

heterocyclic compound binding (ISO)

protein binding (ISO)

protein-containing complex binding (ISO)

quaternary ammonium group binding (ISO)

transmembrane signaling receptor activity (IEA)

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

acetylcholine signaling pathway via nicotinic acetylcholine receptor (ISO)

alfentanil pharmacodynamics pathway (ISO)

bupivacaine pharmacodynamics pathway (ISO)

buprenorphine pharmacodynamics pathway (ISO)

chloroprocaine pharmacodynamics pathway (ISO)

citalopram pharmacodynamics pathway (ISO)

cocaine pharmacodynamics pathway (ISO)

codeine and morphine pharmacodynamics pathway (ISO)

desipramine pharmacodynamics pathway (ISO)

diphenoxylate pharmacodynamics pathway (ISO)

escitalopram pharmacodynamics pathway (ISO)

ethylmorphine pharmacodynamics pathway (ISO)

fentanyl pharmacodynamics pathway (ISO)

fluoxetine pharmacodynamics pathway (ISO)

heroin pharmacodynamics pathway (ISO)

hydrocodone pharmacodynamics pathway (ISO)

hydromorphone pharmacodynamics pathway (ISO)

imipramine pharmacodynamics pathway (ISO)

levacetylmethadol pharmacodynamics pathway (ISO)

levobupivacaine phgarmacodynamics pathway (ISO)

levorphanol pharmacodynamics pathway (ISO)

lidocaine pharmacodynamics pathway (ISO)

mepivacaine pharmacodynamics pathway (ISO)

methadone pharmacodynamics pathway (ISO)

nalbuphine pharmacodynamics pathway (ISO)

naloxone pharmacodynamics pathway (ISO)

naltrexone pharmacodynamics pathway (ISO)

nicotine pharmacodynamics pathway (ISO)

nicotine pharmacokinetics pathway (ISO)

oxybuprocaine pharmacodynamics pathway (ISO)

oxycodone pharmacodynamics pathway (ISO)

oxymorphone pharmacodynamics pathway (ISO)

pentazocine pharmacodynamics pathway (ISO)

prilocaine pharmacodynamics pathway (ISO)

procaine pharmacodynamics pathway (ISO)

remifentanil pharmacodynamics pathway (ISO)

ropivacaine pharmacodynamics pathway (ISO)

tramadol pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CHRNB2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	9,245,803 - 9,255,430 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	9,247,231 - 9,253,795 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	8,581,863 - 8,595,204 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

CHRNB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	154,567,778 - 154,580,013 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	154,567,778 - 154,580,013 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	154,540,254 - 154,552,489 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	152,806,881 - 152,818,978 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	151,353,329 - 151,362,156	NCBI
Celera	1	127,611,891 - 127,623,988 (+)	NCBI		Celera
Cytogenetic Map	1	q21.3	NCBI
HuRef	1	125,903,718 - 125,915,813 (+)	NCBI		HuRef
CHM1_1	1	155,936,657 - 155,948,754 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	153,704,898 - 153,719,720 (+)	NCBI		T2T-CHM13v2.0

Chrnb2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	89,660,755 - 89,671,939 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	89,653,502 - 89,671,939 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	89,753,448 - 89,764,632 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	89,746,195 - 89,764,632 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	89,557,370 - 89,568,554 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	89,839,375 - 89,850,512 (-)	NCBI		MGSCv36	mm8
Celera	3	89,790,490 - 89,801,674 (-)	NCBI		Celera
Cytogenetic Map	3	F1	NCBI
cM Map	3	39.19	NCBI

Chrnb2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	177,479,091 - 177,487,306 (-)	NCBI		GRCr8
mRatBN7.2	2	175,181,402 - 175,189,619 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	175,181,402 - 175,189,619 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	182,330,071 - 182,338,257 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	180,352,453 - 180,360,643 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	174,953,345 - 174,961,538 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	189,088,570 - 189,096,785 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	189,088,570 - 189,096,785 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	208,511,421 - 208,519,636 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	181,961,373 - 181,969,581 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	181,911,478 - 181,919,687 (-)	NCBI
Celera	2	169,123,949 - 169,132,124 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

Chrnb2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955545	1,065,457 - 1,077,526 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955545	1,065,457 - 1,077,056 (+)	NCBI	ChiLan1.0	ChiLan1.0

CHRNB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	95,254,104 - 95,266,251 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	94,986,423 - 94,998,575 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	129,922,740 - 129,931,582 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	133,535,023 - 133,547,361 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	133,535,023 - 133,547,361 (+)	Ensembl	panpan1.1		panPan2

CHRNB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	42,786,505 - 42,797,976 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	42,789,600 - 42,795,722 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	42,277,266 - 42,288,752 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	42,656,510 - 42,668,001 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	42,656,517 - 42,667,042 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	42,435,765 - 42,447,248 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	42,489,629 - 42,501,090 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	42,773,221 - 42,784,709 (-)	NCBI		UU_Cfam_GSD_1.0

Chrnb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	25,136,236 - 25,149,726 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	4,166,619 - 4,186,443 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	4,165,255 - 4,179,285 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CHRNB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	95,198,717 - 95,211,037 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	95,196,992 - 95,211,084 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	104,024,711 - 104,036,882 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Chrnb2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624885	2,843,899 - 2,848,522 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624885	2,839,607 - 2,851,934 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007976963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007976964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007976965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000016568 ⟹ ENSCSAP00000016074

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	20	9,247,231 - 9,253,795 (-)	Ensembl

RefSeq Acc Id:

XM_007976963 ⟹ XP_007975154

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	20	9,245,803 - 9,255,416 (-)	NCBI
Vero_WHO_p1.0	NW_023666038	8,581,863 - 8,595,204 (-)	NCBI

Sequence:

show sequence

CGTCCCAATTGTATTCCCTGGAAGAGCAGCCGGAAAAGCCTCCGCCTGCTCAGACCGGGATAGG
CGAGAAGCTGGTTTCTCCTCGCAGCCGGCTCCCTGAGCCTCAGGAACCACCGAGGCGCCCGGCA
CCACCTGGGCCCAGCTCCAGGCGGGCGCGGCTTCAGCACCACGGACAGCGCCCCGCCCGCGGCC
CTCCCTCTGGCGGCGCGCTCCAGCCGGTGTAGGCGAGGTAGCGAGCTATGCCCGCGGCATGGCC
CGGCGCTGCGGCCCCGTGGCGCTGCTCCTTGGCTTCGGCCTCCTCCGGCTGTGCTCAGGGGTGT
GGGGTACAGATACAGAGGAGCGGCTGGTGGAGCATCTCCTGGATCCTTCCCGCTACAACAAGCT
TATCCGCCCAGCCACCAATGGCTCTGAGCTGGTCACAGTACAGCTCATGGTATCACTGGCCCAG
CTCATCAGTGTGCCTCTCTTCCTCCCTGCAGCATGAGCGGGAGCAGATCATGACCACCAATGTC
TGGCTGACCCAGGAGTGGGAAGATTATCGCCTCACCTGGAAACCTGAAGAGTTTGACAATATGA
AGAAAGTTCGGCTCCCTTCCAAACACATCTGGCTCCCAGATGTGGTCCTGTACAACAATGCTGA
CGGCATGTACGAGGTCTCCTTCTATTCCAATGCGGTGGTCTCCTATGACGGCAGCATCTTCTGG
TTGCCGCCTGCCATCTACAAGAGCGCATGCAAGATTGAAGTAAAGCACTTCCCATTTGACCAGC
AAAACTGCACTATGAAGTTCCGTTCGTGGACCTACGACCGCACGGAGATCGACCTGGTGCTGAA
GAGTGACGTGGCCAGCCTGGACGACTTCACACCTAGTGGTGAGTGGGACATCGTGGCGCTGCCG
GGCCGGCGCAATGAGAACCCCGACGACTCCACGTACGTGGACATCACCTATGACTTCATCATTC
GCCGCAAGCCGCTCTTCTACACCATCAACCTCATCATTCCCTGTGTGCTCATCACCTCACTAGC
CATCCTTGTCTTTTACCTGCCATCCGACTGCGGCGAGAAGATGACGTTGTGCATCTCAGTGCTG
CTGGCGCTCACGGTCTTCCTGCTGCTCATCTCCAAGATCGTGCCTCCCACCTCCCTCGACGTGC
CGCTCGTCGGCAAGTACCTCATGTTCACCATGGTGCTTGTCACCTTCTCCATCGTCACCAGCGT
GTGTGTGCTCAACGTGCACCACCGCTCGCCCACCACGCACACCATGGCGCCCTGGGTGAAGGTT
GTCTTCCTGGAGAAGCTGCCCGCGCTGCTCTTCATGCAGCAGCCACGCCACCATTGCGCCCGCC
AGCGCCTGCGCTTGCGGCGACGTCAGCGTGAGCGCGAGGGCGCCGGAGCCCTCCTCTTCCGCGA
AGCCCCTGGGGCCGACTCCTGCACGTGCTTCGTCAACCGCGCGTCCGTGCAGGGCTTGGCTGGG
GCCTTCGGGGCTGAGCCTGCACCGGTGGCGGGCCCGGGGCGCTCAGGGGAGCCATGTGGCTGTG
GCCTCCGGGAGGCGGTGGACGGCGTGCGCTTCATCGCAGACCACATGCGAAGCGAGGACGACGA
CCAGAGCGTGAGTGAGGACTGGAAGTACGTCGCCATGGTGATCGACCGCCTCTTCCTCTGGATC
TTTGTCTTTGTTTGTGTCTTTGGCACCATTGGCATGTTCCTGCAGCCTCTCTTCCAGAACTACA
CCACCACCACCTTCCTCCACTCAGACCACTCAGCCCCCAGCTCCAAGTGAGGCCCTTCCTCCTC
TCCATGCTCCTTCACCCCGCCACCCTCTGCTGCACAGTAGTGTTGGATGGAGGACGGACGAGTG
AGCTATCAAGAAGAGGGGTGCCGCCCCCACAGATCTATCCTTTTGCTTCATCTGGAGCCCCTCC
TCCCTCACACCTCCATCCACACACAGCAGCTCCAACCTGGAGGCTGGACCAGCTGCTTTCTGTT
TTGGCTGCTCTCCTCCTCTTGTACCAGTCCAGGCAATAGTGTTGATGAGGGAGCAAGGCTGCTG
AGAAGTGGAAGACAGGGATAGCAGAGCCATCTACCTTGAGGAGAGAGTGATGGGCAAGGGGCCA
GGATTGTCTGCTGCCTCCAAGTCATGGGAGAAGAGGAGTCTAGGACAAGGGGTGGAAGGGCAGG
AGCTCAGACCGCACCAGGCTGGCCTGACACAATGGTAGCTCTGAAGGGAGGGGAAGAGGAGAGG
CCTGGGTGTGACCTGACACCTGCCACTACTTGAGTGGACAGTAGCTGGACTGGGTGGGCCTGCC
CAGTAGGTTTAGCCTGGCCCCACTGTCACAGACCCCTGGGGGAGGCTTCCAGATCAGTCCCACA
GCCCCTTGCTTCTAAGGGGTCCAGATACCTGCCCCAGATCCTCTTTCCCCACTGAAGAATTCTG
CGCCCTCTGGACTTCCCTCTCCTTCCTTCCTTCTTCAGGCTCAAGGTGTGGTGGGCAAGGCTGA
GTATTAGGGGAGCTTCTAAGTTCTGAATCTTTGGGTGACCTGCTTGGAGTCTCAGGTCCAAATA
CTTGAACTCTGTGAGAAGTCCAAGTTCATGGGCTTTTGGAACTGGAAGAACTTTGTACAGCCAT
GGATTCCAACATGAGCCATGTTGCAGATGAAGAAACTGACCCACACGGTGATTCAAGCCCAGGT
GGGTCTCTGACTCTTCCTCCCTGCCCTGAGATCCATCTGTCGAGTGCCCTGTTTTTCCCCACTT
TGAACTGACTGGTTACTCGAAGGAAGTGAACTAAGGATGTTAGCTTTAAGCCAGCCCAGCCTCT
TTGCCCACAGCAGAACTGAGGTGAATAGCTGGAACTCTGCTACATCCGTGCTGCTCCAGTCTGT
TCTGCTCGTGGCTCCATCCTTCTGGCTGTTACTCTTCTTCCCCCTCCCAACCAAACCTGAGCAG
CTTTGAAGCAGGACTCGGGAAGGACAGGGCTGCTGCTGCCAGCGACACCTCAGAAAGCATAGCC
TTGGCTTCCTGTCCCTGGAAGCTATACCCTGACTCTGCTCCCAGAGGCCGGCTGGAGGCCACCT
GGCTGGGTAGCCCAGGGAACAGACCTCTTAAGGGATCTCCTGCTTGCTTGTGTTCCCAGCCTGG
GCTCAATGCTGGGCCAGCAGATGGTGGGTTACAGAGGGGTCAGCCTGCCAAATGCACCTGAGGG
ACCTGA

hide sequence

RefSeq Acc Id:

XM_007976964 ⟹ XP_007975155

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	20	9,245,803 - 9,255,430 (-)	NCBI
Vero_WHO_p1.0	NW_023666038	8,581,863 - 8,595,204 (-)	NCBI

Sequence:

show sequence

CTCCTCCCCCTCACCGTCCCAATTGTATTCCCTGGAAGAGCAGCCGGAAAAGCCTCCGCCTGCT
CAGACCGGGATAGGCGAGAAGCTGGTTTCTCCTCGCAGCCGGCTCCCTGAGCCTCAGGAACCAC
CGAGGCGCCCGGCACCACCTGGGCCCAGCTCCAGGCGGGCGCGGCTTCAGCACCACGGACAGCG
CCCCGCCCGCGGCCCTCCCTCTGGCGGCGCGCTCCAGCCGGTGTAGGCGAGGTAGCGAGCTATG
CCCGCGGCATGGCCCGGCGCTGCGGCCCCGTGGCGCTGCTCCTTGGCTTCGGCCTCCTCCGGCT
GTGCTCAGGGGTGTGGGGTACAGATACAGAGGAGCGGCTGGTGGAGCATCTCCTGGATCCTTCC
CGCTACAACAAGCTTATCCGCCCAGCCACCAATGGCTCTGAGCTGGTCACAGTACAGCTCATGG
TATCACTGGCCCAGCTCATCAGTGTGCATGAGCGGGAGCAGATCATGACCACCAATGTCTGGCT
GACCCAGGAGTGGGAAGATTATCGCCTCACCTGGAAACCTGAAGAGTTTGACAATATGAAGAAA
GTTCGGCTCCCTTCCAAACACATCTGGCTCCCAGATGTGGTCCTGTACAACAATGCTGACGGCA
TGTACGAGGTCTCCTTCTATTCCAATGCGGTGGTCTCCTATGACGGCAGCATCTTCTGGTTGCC
GCCTGCCATCTACAAGAGCGCATGCAAGATTGAAGTAAAGCACTTCCCATTTGACCAGCAAAAC
TGCACTATGAAGTTCCGTTCGTGGACCTACGACCGCACGGAGATCGACCTGGTGCTGAAGAGTG
ACGTGGCCAGCCTGGACGACTTCACACCTAGTGGTGAGTGGGACATCGTGGCGCTGCCGGGCCG
GCGCAATGAGAACCCCGACGACTCCACGTACGTGGACATCACCTATGACTTCATCATTCGCCGC
AAGCCGCTCTTCTACACCATCAACCTCATCATTCCCTGTGTGCTCATCACCTCACTAGCCATCC
TTGTCTTTTACCTGCCATCCGACTGCGGCGAGAAGATGACGTTGTGCATCTCAGTGCTGCTGGC
GCTCACGGTCTTCCTGCTGCTCATCTCCAAGATCGTGCCTCCCACCTCCCTCGACGTGCCGCTC
GTCGGCAAGTACCTCATGTTCACCATGGTGCTTGTCACCTTCTCCATCGTCACCAGCGTGTGTG
TGCTCAACGTGCACCACCGCTCGCCCACCACGCACACCATGGCGCCCTGGGTGAAGGTTGTCTT
CCTGGAGAAGCTGCCCGCGCTGCTCTTCATGCAGCAGCCACGCCACCATTGCGCCCGCCAGCGC
CTGCGCTTGCGGCGACGTCAGCGTGAGCGCGAGGGCGCCGGAGCCCTCCTCTTCCGCGAAGCCC
CTGGGGCCGACTCCTGCACGTGCTTCGTCAACCGCGCGTCCGTGCAGGGCTTGGCTGGGGCCTT
CGGGGCTGAGCCTGCACCGGTGGCGGGCCCGGGGCGCTCAGGGGAGCCATGTGGCTGTGGCCTC
CGGGAGGCGGTGGACGGCGTGCGCTTCATCGCAGACCACATGCGAAGCGAGGACGACGACCAGA
GCGTGAGTGAGGACTGGAAGTACGTCGCCATGGTGATCGACCGCCTCTTCCTCTGGATCTTTGT
CTTTGTTTGTGTCTTTGGCACCATTGGCATGTTCCTGCAGCCTCTCTTCCAGAACTACACCACC
ACCACCTTCCTCCACTCAGACCACTCAGCCCCCAGCTCCAAGTGAGGCCCTTCCTCCTCTCCAT
GCTCCTTCACCCCGCCACCCTCTGCTGCACAGTAGTGTTGGATGGAGGACGGACGAGTGAGCTA
TCAAGAAGAGGGGTGCCGCCCCCACAGATCTATCCTTTTGCTTCATCTGGAGCCCCTCCTCCCT
CACACCTCCATCCACACACAGCAGCTCCAACCTGGAGGCTGGACCAGCTGCTTTCTGTTTTGGC
TGCTCTCCTCCTCTTGTACCAGTCCAGGCAATAGTGTTGATGAGGGAGCAAGGCTGCTGAGAAG
TGGAAGACAGGGATAGCAGAGCCATCTACCTTGAGGAGAGAGTGATGGGCAAGGGGCCAGGATT
GTCTGCTGCCTCCAAGTCATGGGAGAAGAGGAGTCTAGGACAAGGGGTGGAAGGGCAGGAGCTC
AGACCGCACCAGGCTGGCCTGACACAATGGTAGCTCTGAAGGGAGGGGAAGAGGAGAGGCCTGG
GTGTGACCTGACACCTGCCACTACTTGAGTGGACAGTAGCTGGACTGGGTGGGCCTGCCCAGTA
GGTTTAGCCTGGCCCCACTGTCACAGACCCCTGGGGGAGGCTTCCAGATCAGTCCCACAGCCCC
TTGCTTCTAAGGGGTCCAGATACCTGCCCCAGATCCTCTTTCCCCACTGAAGAATTCTGCGCCC
TCTGGACTTCCCTCTCCTTCCTTCCTTCTTCAGGCTCAAGGTGTGGTGGGCAAGGCTGAGTATT
AGGGGAGCTTCTAAGTTCTGAATCTTTGGGTGACCTGCTTGGAGTCTCAGGTCCAAATACTTGA
ACTCTGTGAGAAGTCCAAGTTCATGGGCTTTTGGAACTGGAAGAACTTTGTACAGCCATGGATT
CCAACATGAGCCATGTTGCAGATGAAGAAACTGACCCACACGGTGATTCAAGCCCAGGTGGGTC
TCTGACTCTTCCTCCCTGCCCTGAGATCCATCTGTCGAGTGCCCTGTTTTTCCCCACTTTGAAC
TGACTGGTTACTCGAAGGAAGTGAACTAAGGATGTTAGCTTTAAGCCAGCCCAGCCTCTTTGCC
CACAGCAGAACTGAGGTGAATAGCTGGAACTCTGCTACATCCGTGCTGCTCCAGTCTGTTCTGC
TCGTGGCTCCATCCTTCTGGCTGTTACTCTTCTTCCCCCTCCCAACCAAACCTGAGCAGCTTTG
AAGCAGGACTCGGGAAGGACAGGGCTGCTGCTGCCAGCGACACCTCAGAAAGCATAGCCTTGGC
TTCCTGTCCCTGGAAGCTATACCCTGACTCTGCTCCCAGAGGCCGGCTGGAGGCCACCTGGCTG
GGTAGCCCAGGGAACAGACCTCTTAAGGGATCTCCTGCTTGCTTGTGTTCCCAGCCTGGGCTCA
ATGCTGGGCCAGCAGATGGTGGGTTACAGAGGGGTCAGCCTGCCAAATGCACCTGAGGGACCTG
A

hide sequence

RefSeq Acc Id:

XM_007976965 ⟹ XP_007975156

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	20	9,245,803 - 9,255,416 (-)	NCBI
Vero_WHO_p1.0	NW_023666038	8,581,863 - 8,595,204 (-)	NCBI

Sequence:

show sequence

CGTCCCAATTGTATTCCCTGGAAGAGCAGCCGGAAAAGCCTCCGCCTGCTCAGACCGGGATAGG
CGAGAAGCTGGTTTCTCCTCGCAGCCGGCTCCCTGAGCCTCAGGAACCACCGAGGCGCCCGGCA
CCACCTGGGCCCAGCTCCAGGCGGGCGCGGCTTCAGCACCACGGACAGCGCCCCGCCCGCGGCC
CTCCCTCTGGCGGCGCGCTCCAGCCGGTGTAGGCGAGGTAGCGAGCTATGCCCGCGGCATGGCC
CGGCGCTGCGGCCCCGTGGCGCTGCTCCTTGGCTTCGGCCTCCTCCGGCTGTGCTCAGGGGTGT
GGGGTACAGATACAGAGGAGCGGCTGGTGGAGCATCTCCTGGATCCTTCCCGCTACAACAAGCT
TATCCGCCCAGCCACCAATGGCTCTGAGCTGGTCACAGTACAGCTCATGGTATCACTGGCCCAG
CTCATCAGTGTGGAGTGGGAAGATTATCGCCTCACCTGGAAACCTGAAGAGTTTGACAATATGA
AGAAAGTTCGGCTCCCTTCCAAACACATCTGGCTCCCAGATGTGGTCCTGTACAACAATGCTGA
CGGCATGTACGAGGTCTCCTTCTATTCCAATGCGGTGGTCTCCTATGACGGCAGCATCTTCTGG
TTGCCGCCTGCCATCTACAAGAGCGCATGCAAGATTGAAGTAAAGCACTTCCCATTTGACCAGC
AAAACTGCACTATGAAGTTCCGTTCGTGGACCTACGACCGCACGGAGATCGACCTGGTGCTGAA
GAGTGACGTGGCCAGCCTGGACGACTTCACACCTAGTGGTGAGTGGGACATCGTGGCGCTGCCG
GGCCGGCGCAATGAGAACCCCGACGACTCCACGTACGTGGACATCACCTATGACTTCATCATTC
GCCGCAAGCCGCTCTTCTACACCATCAACCTCATCATTCCCTGTGTGCTCATCACCTCACTAGC
CATCCTTGTCTTTTACCTGCCATCCGACTGCGGCGAGAAGATGACGTTGTGCATCTCAGTGCTG
CTGGCGCTCACGGTCTTCCTGCTGCTCATCTCCAAGATCGTGCCTCCCACCTCCCTCGACGTGC
CGCTCGTCGGCAAGTACCTCATGTTCACCATGGTGCTTGTCACCTTCTCCATCGTCACCAGCGT
GTGTGTGCTCAACGTGCACCACCGCTCGCCCACCACGCACACCATGGCGCCCTGGGTGAAGGTT
GTCTTCCTGGAGAAGCTGCCCGCGCTGCTCTTCATGCAGCAGCCACGCCACCATTGCGCCCGCC
AGCGCCTGCGCTTGCGGCGACGTCAGCGTGAGCGCGAGGGCGCCGGAGCCCTCCTCTTCCGCGA
AGCCCCTGGGGCCGACTCCTGCACGTGCTTCGTCAACCGCGCGTCCGTGCAGGGCTTGGCTGGG
GCCTTCGGGGCTGAGCCTGCACCGGTGGCGGGCCCGGGGCGCTCAGGGGAGCCATGTGGCTGTG
GCCTCCGGGAGGCGGTGGACGGCGTGCGCTTCATCGCAGACCACATGCGAAGCGAGGACGACGA
CCAGAGCGTGAGTGAGGACTGGAAGTACGTCGCCATGGTGATCGACCGCCTCTTCCTCTGGATC
TTTGTCTTTGTTTGTGTCTTTGGCACCATTGGCATGTTCCTGCAGCCTCTCTTCCAGAACTACA
CCACCACCACCTTCCTCCACTCAGACCACTCAGCCCCCAGCTCCAAGTGAGGCCCTTCCTCCTC
TCCATGCTCCTTCACCCCGCCACCCTCTGCTGCACAGTAGTGTTGGATGGAGGACGGACGAGTG
AGCTATCAAGAAGAGGGGTGCCGCCCCCACAGATCTATCCTTTTGCTTCATCTGGAGCCCCTCC
TCCCTCACACCTCCATCCACACACAGCAGCTCCAACCTGGAGGCTGGACCAGCTGCTTTCTGTT
TTGGCTGCTCTCCTCCTCTTGTACCAGTCCAGGCAATAGTGTTGATGAGGGAGCAAGGCTGCTG
AGAAGTGGAAGACAGGGATAGCAGAGCCATCTACCTTGAGGAGAGAGTGATGGGCAAGGGGCCA
GGATTGTCTGCTGCCTCCAAGTCATGGGAGAAGAGGAGTCTAGGACAAGGGGTGGAAGGGCAGG
AGCTCAGACCGCACCAGGCTGGCCTGACACAATGGTAGCTCTGAAGGGAGGGGAAGAGGAGAGG
CCTGGGTGTGACCTGACACCTGCCACTACTTGAGTGGACAGTAGCTGGACTGGGTGGGCCTGCC
CAGTAGGTTTAGCCTGGCCCCACTGTCACAGACCCCTGGGGGAGGCTTCCAGATCAGTCCCACA
GCCCCTTGCTTCTAAGGGGTCCAGATACCTGCCCCAGATCCTCTTTCCCCACTGAAGAATTCTG
CGCCCTCTGGACTTCCCTCTCCTTCCTTCCTTCTTCAGGCTCAAGGTGTGGTGGGCAAGGCTGA
GTATTAGGGGAGCTTCTAAGTTCTGAATCTTTGGGTGACCTGCTTGGAGTCTCAGGTCCAAATA
CTTGAACTCTGTGAGAAGTCCAAGTTCATGGGCTTTTGGAACTGGAAGAACTTTGTACAGCCAT
GGATTCCAACATGAGCCATGTTGCAGATGAAGAAACTGACCCACACGGTGATTCAAGCCCAGGT
GGGTCTCTGACTCTTCCTCCCTGCCCTGAGATCCATCTGTCGAGTGCCCTGTTTTTCCCCACTT
TGAACTGACTGGTTACTCGAAGGAAGTGAACTAAGGATGTTAGCTTTAAGCCAGCCCAGCCTCT
TTGCCCACAGCAGAACTGAGGTGAATAGCTGGAACTCTGCTACATCCGTGCTGCTCCAGTCTGT
TCTGCTCGTGGCTCCATCCTTCTGGCTGTTACTCTTCTTCCCCCTCCCAACCAAACCTGAGCAG
CTTTGAAGCAGGACTCGGGAAGGACAGGGCTGCTGCTGCCAGCGACACCTCAGAAAGCATAGCC
TTGGCTTCCTGTCCCTGGAAGCTATACCCTGACTCTGCTCCCAGAGGCCGGCTGGAGGCCACCT
GGCTGGGTAGCCCAGGGAACAGACCTCTTAAGGGATCTCCTGCTTGCTTGTGTTCCCAGCCTGG
GCTCAATGCTGGGCCAGCAGATGGTGGGTTACAGAGGGGTCAGCCTGCCAAATGCACCTGAGGG
ACCTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007975154	(Get FASTA)	NCBI Sequence Viewer
	XP_007975155	(Get FASTA)	NCBI Sequence Viewer
	XP_007975156	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000016074
	ENSCSAP00000016074.1

RefSeq Acc Id:	XP_007975155 ⟸ XM_007976964
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9S5D5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007975156 ⟸ XM_007976965
- Peptide Label:	isoform X3
- UniProtKB:	A0A0D9S5D5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007975154 ⟸ XM_007976963
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9S5D5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000016074 ⟸ ENSCSAT00000016568

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000001961	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000016568.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.58.390	UniProtKB/TrEMBL
	2.70.170.10	UniProtKB/TrEMBL
InterPro	Neur_chan_lig-bd	UniProtKB/TrEMBL
	Neur_chan_lig-bd_sf	UniProtKB/TrEMBL
	Neur_channel	UniProtKB/TrEMBL
	Neuro-gated_channel_TM_sf	UniProtKB/TrEMBL
	Neuro_actylchol_rec	UniProtKB/TrEMBL
	Neurotrans-gated_channel_TM	UniProtKB/TrEMBL
	Neurotransmitter_ion_chnl_CS	UniProtKB/TrEMBL
	Nicotinic_acetylcholine_rcpt	UniProtKB/TrEMBL
NCBI Gene	CHRNB2	ENTREZGENE
PANTHER	NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-2	UniProtKB/TrEMBL
	PTHR18945	UniProtKB/TrEMBL
Pfam	Neur_chan_LBD	UniProtKB/TrEMBL
	Neur_chan_memb	UniProtKB/TrEMBL
PRINTS	NICOTINICR	UniProtKB/TrEMBL
	NRIONCHANNEL	UniProtKB/TrEMBL
PROSITE	NEUROTR_ION_CHANNEL	UniProtKB/TrEMBL
Superfamily-SCOP	SSF63712	UniProtKB/TrEMBL
	SSF90112	UniProtKB/TrEMBL
UniProt	A0A0D9S5D5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Annotations - SMPDB

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Imported Disease Annotations - OMIM

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Imported Annotations - SMPDB