DOCK11 (dedicator of cytokinesis 11) - Rat Genome Database

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Gene: DOCK11 (dedicator of cytokinesis 11) Chlorocebus sabaeus
Analyze
Symbol: DOCK11
Name: dedicator of cytokinesis 11
RGD ID: 18512081
Description: ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN B cell homeostasis (ortholog); ASSOCIATED WITH autistic disorder (ortholog); AUTOINFLAMMATORY DISEASE, MULTISYSTEM, WITH IMMUNE DYSREGULATION, X-LINKED (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dedicator of cytokinesis protein 11
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606531,235,397 - 31,427,571 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
DOCK11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606531,235,397 - 31,427,571 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
DOCK11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X118,495,815 - 118,686,147 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX118,495,815 - 118,686,163 (+)EnsemblGRCh38hg38GRCh38
GRCh37X117,629,778 - 117,820,110 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X117,513,900 - 117,704,151 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X117,411,752 - 117,601,990NCBI
CeleraX118,084,625 - 118,274,886 (+)NCBICelera
Cytogenetic MapXq24NCBI
HuRefX107,125,453 - 107,314,333 (+)NCBIHuRef
CHM1_1X117,540,714 - 117,731,102 (+)NCBICHM1_1
T2T-CHM13v2.0X116,873,439 - 117,063,900 (+)NCBIT2T-CHM13v2.0
Dock11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X35,150,924 - 35,340,223 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX35,152,485 - 35,340,215 (+)EnsemblGRCm39 Ensembl
GRCm38X35,887,271 - 36,076,570 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX35,888,832 - 36,076,562 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X33,428,827 - 33,616,557 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X32,320,277 - 32,508,502 (+)NCBIMGSCv36mm8
CeleraX22,618,373 - 22,805,356 (+)NCBICelera
Cytogenetic MapXA3.3NCBI
cM MapX20.35NCBI
Dock11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X119,997,523 - 120,180,643 (+)NCBIGRCr8
mRatBN7.2X115,131,720 - 115,314,854 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX115,131,909 - 115,314,854 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX117,230,378 - 117,415,458 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X120,799,457 - 120,984,532 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X118,345,645 - 118,530,732 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X122,507,169 - 122,690,463 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX122,507,374 - 122,690,465 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X122,657,080 - 122,840,107 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X8,854,523 - 9,037,434 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX114,369,269 - 114,551,013 (+)NCBICelera
Cytogenetic MapXq34NCBI
Dock11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555341,239,247 - 1,431,714 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555341,239,241 - 1,431,714 (-)NCBIChiLan1.0ChiLan1.0
DOCK11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X117,853,747 - 118,045,002 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X117,857,481 - 118,056,339 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X107,502,955 - 107,694,069 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X117,954,489 - 118,161,355 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX117,952,995 - 118,161,009 (+)Ensemblpanpan1.1panPan2
DOCK11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X90,752,726 - 90,892,931 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX90,716,197 - 90,892,062 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX76,779,939 - 76,967,627 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X92,444,383 - 92,632,098 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX92,444,366 - 92,632,088 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X89,897,307 - 90,085,283 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X91,649,194 - 91,844,023 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X91,384,644 - 91,572,351 (+)NCBIUU_Cfam_GSD_1.0
Dock11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X89,653,085 - 89,839,118 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647911,148,626 - 11,334,452 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647911,148,877 - 11,334,381 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DOCK11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX97,068,355 - 97,267,517 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X97,068,488 - 97,267,528 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X114,419,897 - 114,607,243 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Dock11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248952,482,308 - 2,662,550 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248952,482,257 - 2,663,267 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 12 20 34
Low 24 26
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: XM_037989079   ⟹   XP_037845007
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606531,235,397 - 31,427,571 (+)NCBI
RefSeq Acc Id: XM_037989080   ⟹   XP_037845008
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606531,235,579 - 31,427,571 (+)NCBI
RefSeq Acc Id: XM_037989081   ⟹   XP_037845009
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606531,235,660 - 31,427,571 (+)NCBI
RefSeq Acc Id: XM_037989082   ⟹   XP_037845010
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606531,236,653 - 31,427,571 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037845007 (Get FASTA)   NCBI Sequence Viewer  
  XP_037845008 (Get FASTA)   NCBI Sequence Viewer  
  XP_037845009 (Get FASTA)   NCBI Sequence Viewer  
  XP_037845010 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000014379.1
Reference Protein Sequences
RefSeq Acc Id: XP_037845007   ⟸   XM_037989079
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S0J0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037845008   ⟸   XM_037989080
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S0J0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037845009   ⟸   XM_037989081
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S0J0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037845010   ⟸   XM_037989082
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S0J0 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018380 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016470.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.740 UniProtKB/TrEMBL
  1.25.40.410 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  C2_Dock-D UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  DHR-1_domain UniProtKB/TrEMBL
  DHR-2 UniProtKB/TrEMBL
  DOCK UniProtKB/TrEMBL
  DOCK_C/D_N UniProtKB/TrEMBL
  DOCK_C_lobe_A UniProtKB/TrEMBL
  DOCK_C_lobe_C UniProtKB/TrEMBL
  DOCKER_Lobe_A UniProtKB/TrEMBL
  DOCKER_Lobe_B UniProtKB/TrEMBL
  DOCKER_Lobe_C UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene DOCK11 ENTREZGENE
PANTHER DEDICATOR OF CYTOKINESIS PROTEIN 11 UniProtKB/TrEMBL
  PTHR23317 UniProtKB/TrEMBL
Pfam DHR-2 UniProtKB/TrEMBL
  DHR-2_Lobe_B UniProtKB/TrEMBL
  DHR-2_Lobe_C UniProtKB/TrEMBL
  DOCK-C2 UniProtKB/TrEMBL
  DUF3398 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
PROSITE DHR_1 UniProtKB/TrEMBL
  DHR_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
UniProt A0A0D9S0J0 ENTREZGENE, UniProtKB/TrEMBL