FOLR2 (folate receptor beta) - Rat Genome Database

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Gene: FOLR2 (folate receptor beta) Chlorocebus sabaeus
Analyze
Symbol: FOLR2
Name: folate receptor beta
RGD ID: 18508547
Description: ENCODES a protein that exhibits folic acid binding (ortholog); folic acid receptor activity (ortholog); INVOLVED IN folic acid transport (ortholog); monocyte chemotaxis (ortholog); positive regulation of cell population proliferation (ortholog); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); autism spectrum disorder (ortholog); cerebral folate receptor alpha deficiency (ortholog); FOUND IN cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,436,430 - 63,441,924 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl163,436,684 - 63,441,743 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604362,442,495 - 62,447,826 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FOLR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,436,430 - 63,441,924 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl163,436,684 - 63,441,743 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604362,442,495 - 62,447,826 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FOLR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381172,216,794 - 72,221,950 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1172,216,601 - 72,221,950 (+)EnsemblGRCh38hg38GRCh38
GRCh371171,927,838 - 71,932,994 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361171,605,488 - 71,610,637 (+)NCBINCBI36Build 36hg18NCBI36
Build 341171,605,490 - 71,610,635NCBI
Celera1169,229,223 - 69,234,398 (+)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1168,220,979 - 68,226,155 (+)NCBIHuRef
CHM1_11171,811,270 - 71,816,445 (+)NCBICHM1_1
T2T-CHM13v2.01172,143,410 - 72,148,566 (+)NCBIT2T-CHM13v2.0
Folr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397101,489,195 - 101,506,397 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7101,489,195 - 101,506,401 (-)EnsemblGRCm39 Ensembl
GRCm387101,839,988 - 101,857,190 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7101,839,988 - 101,857,194 (-)EnsemblGRCm38mm10GRCm38
MGSCv377108,988,502 - 109,005,704 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367101,713,809 - 101,731,011 (-)NCBIMGSCv36mm8
Celera7102,211,727 - 102,229,006 (-)NCBICelera
Cytogenetic Map7E2NCBI
cM Map754.67NCBI
Folr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81165,612,047 - 165,630,382 (-)NCBIGRCr8
mRatBN7.21156,200,044 - 156,218,380 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1156,200,060 - 156,205,724 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1164,190,379 - 164,208,686 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01171,370,469 - 171,388,780 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01164,247,973 - 164,266,440 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01166,915,045 - 166,933,377 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,915,045 - 166,919,302 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,104,830 - 173,123,162 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41159,295,773 - 159,314,107 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11159,374,969 - 159,379,040 (-)NCBI
Celera1154,279,465 - 154,297,790 (-)NCBICelera
Cytogenetic Map1q32NCBI
FOLR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2973,163,720 - 73,168,884 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11174,207,141 - 74,212,292 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01167,295,305 - 67,300,463 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11170,518,931 - 70,524,088 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1170,518,931 - 70,524,088 (+)Ensemblpanpan1.1panPan2
LOC476816
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12125,917,476 - 25,923,267 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2125,687,133 - 25,692,920 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02126,126,072 - 26,131,869 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12125,917,551 - 25,923,336 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02126,133,737 - 26,139,526 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02126,035,288 - 26,041,078 (-)NCBIUU_Cfam_GSD_1.0
Folr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494759,917,164 - 59,922,642 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364981,516,710 - 1,522,347 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364981,516,719 - 1,522,187 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOLR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl96,785,303 - 6,790,465 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.196,785,308 - 6,790,466 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.297,546,813 - 7,551,961 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC101721569
(Heterocephalus glaber - naked mole-rat)		 No map positions available.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 36 16 59
Below cutoff 4 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000002189   ⟹   ENSCSAP00000000516
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl163,436,684 - 63,441,743 (+)Ensembl
RefSeq Acc Id: XM_008020017   ⟹   XP_008018208
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1163,436,434 - 63,441,924 (+)NCBI
Vero_WHO_p1.0NW_02366604362,442,495 - 62,447,791 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038005519   ⟹   XP_037861447
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604362,442,495 - 62,447,826 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008018208 (Get FASTA)   NCBI Sequence Viewer  
  XP_037861447 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000000516
  ENSCSAP00000000516.1
Reference Protein Sequences
RefSeq Acc Id: XP_008018208   ⟸   XM_008020017
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QVX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000000516   ⟸   ENSCSAT00000002189
RefSeq Acc Id: XP_037861447   ⟸   XM_038005519
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QVX7 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004161 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002189.1 UniProtKB/TrEMBL
InterPro Folate_rcpt UniProtKB/TrEMBL
  Folate_rcpt-like UniProtKB/TrEMBL
NCBI Gene FOLR2 ENTREZGENE
PANTHER PTHR10517 UniProtKB/TrEMBL
  PTHR10517:SF8 UniProtKB/TrEMBL
Pfam Folate_rec UniProtKB/TrEMBL
UniProt A0A0D9QVX7 ENTREZGENE, UniProtKB/TrEMBL