GRIP1 (glutamate receptor interacting protein 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: GRIP1 (glutamate receptor interacting protein 1) Chlorocebus sabaeus
Analyze
Symbol: GRIP1
Name: glutamate receptor interacting protein 1
RGD ID: 18503326
Description: ENCODES a protein that exhibits GTPase binding (ortholog); ionotropic glutamate receptor binding (ortholog); PDZ domain binding (ortholog); INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to phorbol 13-acetate 12-myristate (ortholog); cerebral cortex development (ortholog); ASSOCIATED WITH clubfoot (ortholog); Fraser syndrome (ortholog); Fraser syndrome 1 (ortholog); FOUND IN dendrite (ortholog); dendritic shaft (ortholog); dendritic spine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glutamate receptor-interacting protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11162,018,037 - 62,464,440 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1162,015,463 - 62,335,876 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037182,985,387 - 183,705,463 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
GRIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11162,018,037 - 62,464,440 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1162,015,463 - 62,335,876 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037182,985,387 - 183,705,463 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
GRIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381266,347,431 - 67,069,338 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1266,347,431 - 67,069,162 (-)EnsemblGRCh38hg38GRCh38
GRCh371266,741,211 - 67,463,118 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361265,029,066 - 65,359,020 (-)NCBINCBI36Build 36hg18NCBI36
Build 341265,028,871 - 65,145,401NCBI
Celera1266,405,432 - 66,737,052 (-)NCBICelera
Cytogenetic Map12q14.3NCBI
HuRef1263,792,018 - 64,123,720 (-)NCBIHuRef
CHM1_11266,708,221 - 67,039,968 (-)NCBICHM1_1
T2T-CHM13v2.01266,326,883 - 67,048,770 (-)NCBIT2T-CHM13v2.0
Grip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910119,289,810 - 119,923,172 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10119,289,735 - 119,923,166 (+)EnsemblGRCm39 Ensembl
GRCm3810119,453,238 - 120,087,267 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10119,453,830 - 120,087,261 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710118,891,370 - 119,512,653 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610118,857,374 - 119,478,657 (+)NCBIMGSCv36mm8
Celera10121,814,033 - 122,436,941 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1067.33NCBI
Grip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8756,820,501 - 57,477,877 (+)NCBIGRCr8
mRatBN7.2754,934,856 - 55,592,274 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl754,934,250 - 55,592,273 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx757,218,667 - 57,489,247 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0759,421,818 - 59,692,413 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0759,199,652 - 59,469,780 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0764,672,723 - 64,854,939 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl764,672,722 - 64,864,404 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0764,890,319 - 65,072,097 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4759,157,276 - 59,306,131 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1759,170,845 - 59,326,858 (+)NCBI
Celera752,073,046 - 52,340,208 (+)NCBICelera
Cytogenetic Map7q22NCBI
Grip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545812,967,089 - 13,214,838 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545812,970,858 - 13,179,369 (-)NCBIChiLan1.0ChiLan1.0
GRIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21027,286,061 - 28,012,479 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11227,282,825 - 28,004,487 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01221,841,611 - 22,562,418 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11222,826,257 - 23,069,480 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1222,744,177 - 23,069,480 (+)Ensemblpanpan1.1panPan2
GRIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1108,801,023 - 9,187,684 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl108,802,529 - 9,063,848 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha108,731,329 - 9,389,361 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0108,912,752 - 9,572,589 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl108,914,210 - 9,176,615 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1108,789,226 - 9,449,620 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0109,034,586 - 9,695,263 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0109,155,858 - 9,816,627 (-)NCBIUU_Cfam_GSD_1.0
Grip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494549,107,221 - 49,757,054 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365454,353,040 - 5,002,725 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365454,353,056 - 4,606,196 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl530,697,040 - 31,020,901 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1530,697,018 - 31,175,412 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2533,972,164 - 34,714,229 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Grip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248021,264,833 - 1,964,202 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248021,558,364 - 1,954,695 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 15
Low 36 20 45
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008003932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008003933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008003934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008003935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008003936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008003937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008003938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037987711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037987719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037987730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037987732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037987734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037987740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037987743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037987749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000002386   ⟹   ENSCSAP00000000702
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1162,015,463 - 62,335,876 (-)Ensembl
RefSeq Acc Id: XM_008003932   ⟹   XP_008002123
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11162,018,037 - 62,464,440 (-)NCBI
Vero_WHO_p1.0NW_023666037183,258,310 - 183,705,445 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008003933   ⟹   XP_008002124
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11162,018,037 - 62,464,440 (-)NCBI
Vero_WHO_p1.0NW_023666037183,258,310 - 183,703,907 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008003934   ⟹   XP_008002125
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11162,018,037 - 62,338,355 (-)NCBI
Vero_WHO_p1.0NW_023666037183,382,965 - 183,705,445 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008003935   ⟹   XP_008002126
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11162,018,037 - 62,464,440 (-)NCBI
Vero_WHO_p1.0NW_023666037183,261,501 - 183,705,445 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008003936   ⟹   XP_008002127
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11162,018,037 - 62,464,440 (-)NCBI
Vero_WHO_p1.0NW_023666037183,261,501 - 183,705,445 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008003937   ⟹   XP_008002128
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11162,018,037 - 62,338,355 (-)NCBI
Vero_WHO_p1.0NW_023666037183,382,965 - 183,705,445 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008003938   ⟹   XP_008002129
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11162,018,037 - 62,338,355 (-)NCBI
Vero_WHO_p1.0NW_023666037183,382,965 - 183,705,445 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037987711   ⟹   XP_037843639
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037183,258,310 - 183,705,463 (+)NCBI
RefSeq Acc Id: XM_037987719   ⟹   XP_037843647
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037182,985,387 - 183,703,891 (+)NCBI
RefSeq Acc Id: XM_037987730   ⟹   XP_037843658
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037183,382,965 - 183,705,445 (+)NCBI
RefSeq Acc Id: XM_037987732   ⟹   XP_037843660
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037182,985,387 - 183,705,463 (+)NCBI
RefSeq Acc Id: XM_037987734   ⟹   XP_037843662
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037183,261,501 - 183,705,445 (+)NCBI
RefSeq Acc Id: XM_037987740   ⟹   XP_037843668
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037183,261,501 - 183,705,445 (+)NCBI
RefSeq Acc Id: XM_037987743   ⟹   XP_037843671
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037182,985,682 - 183,705,445 (+)NCBI
RefSeq Acc Id: XM_037987749   ⟹   XP_037843677
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037182,985,682 - 183,705,445 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008002127   ⟸   XM_008003936
- Peptide Label: isoform X10
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008002126   ⟸   XM_008003935
- Peptide Label: isoform X8
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008002124   ⟸   XM_008003933
- Peptide Label: isoform X3
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008002123   ⟸   XM_008003932
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008002129   ⟸   XM_008003938
- Peptide Label: isoform X14
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008002128   ⟸   XM_008003937
- Peptide Label: isoform X13
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008002125   ⟸   XM_008003934
- Peptide Label: isoform X5
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000000702   ⟸   ENSCSAT00000002386
RefSeq Acc Id: XP_037843660   ⟸   XM_037987732
- Peptide Label: isoform X7
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843647   ⟸   XM_037987719
- Peptide Label: isoform X4
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843671   ⟸   XM_037987743
- Peptide Label: isoform X12
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843677   ⟸   XM_037987749
- Peptide Label: isoform X15
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843639   ⟸   XM_037987711
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843662   ⟸   XM_037987734
- Peptide Label: isoform X9
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843668   ⟸   XM_037987740
- Peptide Label: isoform X11
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843658   ⟸   XM_037987730
- Peptide Label: isoform X6
- UniProtKB: A0A0D9QWG3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004360 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002386.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
InterPro GRIP1/2 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_6 UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
NCBI Gene GRIP1 ENTREZGENE
PANTHER PTHR46227 UniProtKB/TrEMBL
  PTHR46227:SF3 UniProtKB/TrEMBL
Pfam PDZ UniProtKB/TrEMBL
  PDZ_6 UniProtKB/TrEMBL
PROSITE PDZ UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
Superfamily-SCOP SSF50156 UniProtKB/TrEMBL
UniProt A0A0D9QWG3 ENTREZGENE, UniProtKB/TrEMBL