VPS26A (VPS26, retromer complex component A) - Rat Genome Database

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Gene: VPS26A (VPS26, retromer complex component A) Chlorocebus sabaeus
Analyze
Symbol: VPS26A
Name: VPS26, retromer complex component A (Ensembl:VPS26 retromer complex component A)
RGD ID: 18502176
Description: INVOLVED IN endocytic recycling (ortholog); retrograde transport, endosome to Golgi (ortholog); PARTICIPATES IN retromer-mediated pathway; ASSOCIATED WITH diabetic retinopathy (ortholog); genetic disease (ortholog); type 2 diabetes mellitus (ortholog); FOUND IN lysosome (ortholog); retromer, cargo-selective complex (ortholog); tubular endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: vacuolar protein sorting-associated protein 26A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1962,148,194 - 62,199,167 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl962,148,025 - 62,199,447 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604822,888,357 - 22,939,899 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
VPS26A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1962,148,194 - 62,199,167 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl962,148,025 - 62,199,447 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604822,888,357 - 22,939,899 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
VPS26A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381069,124,178 - 69,174,412 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1069,123,512 - 69,174,412 (+)EnsemblGRCh38hg38GRCh38
GRCh371070,883,934 - 70,934,168 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361070,553,914 - 70,602,623 (+)NCBINCBI36Build 36hg18NCBI36
Build 341070,553,961 - 70,602,620NCBI
Celera1064,159,753 - 64,208,441 (+)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1064,883,995 - 64,932,609 (+)NCBIHuRef
CHM1_11071,165,664 - 71,214,351 (+)NCBICHM1_1
T2T-CHM13v2.01069,991,871 - 70,042,751 (+)NCBIT2T-CHM13v2.0
Vps26a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391062,290,622 - 62,322,584 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1062,291,014 - 62,322,584 (-)EnsemblGRCm39 Ensembl
GRCm381062,454,843 - 62,486,805 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1062,455,235 - 62,486,805 (-)EnsemblGRCm38mm10GRCm38
MGSCv371061,917,591 - 61,949,553 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361061,850,629 - 61,882,109 (-)NCBIMGSCv36mm8
Celera1063,558,008 - 63,589,887 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.41NCBI
Vps26a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82030,947,018 - 30,976,964 (-)NCBIGRCr8
mRatBN7.22030,404,320 - 30,434,266 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2030,404,325 - 30,434,131 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2031,416,512 - 31,445,105 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02030,807,416 - 30,836,009 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02031,544,156 - 31,572,783 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02032,085,465 - 32,115,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2032,086,746 - 32,115,357 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02033,873,719 - 33,903,564 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42029,709,097 - 29,737,707 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12029,722,899 - 29,751,507 (-)NCBI
Celera2031,825,749 - 31,854,343 (-)NCBICelera
Cytogenetic Map20q11NCBI
Vps26a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543721,910,680 - 21,944,428 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543721,911,111 - 21,944,888 (-)NCBIChiLan1.0ChiLan1.0
VPS26A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2881,270,600 - 81,319,081 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11081,275,921 - 81,324,403 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01065,591,415 - 65,639,894 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11068,125,404 - 68,173,317 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1068,125,409 - 68,173,317 (+)Ensemblpanpan1.1panPan2
VPS26A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1420,265,120 - 20,296,125 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl420,264,905 - 20,294,674 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha420,395,086 - 20,426,407 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0420,537,258 - 20,568,348 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl420,512,281 - 20,568,600 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1420,437,714 - 20,469,018 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0420,640,702 - 20,672,002 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0420,984,094 - 21,015,442 (+)NCBIUU_Cfam_GSD_1.0
Vps26a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721360,776,985 - 60,815,318 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365219,269,287 - 9,308,153 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365219,269,714 - 9,308,016 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VPS26A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1472,210,520 - 72,241,440 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11472,210,486 - 72,241,441 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21478,227,157 - 78,258,126 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Vps26a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247543,425,706 - 3,468,037 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247543,425,614 - 3,468,037 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 2 50
Low 18 10
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000005844   ⟹   ENSCSAP00000004060
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl962,148,025 - 62,199,447 (-)Ensembl
RefSeq Acc Id: XM_038009139   ⟹   XP_037865067
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604822,888,357 - 22,939,899 (-)NCBI
RefSeq Acc Id: XM_038009140   ⟹   XP_037865068
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604822,888,357 - 22,939,896 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037865067 (Get FASTA)   NCBI Sequence Viewer  
  XP_037865068 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004060.1
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000004060   ⟸   ENSCSAT00000005844
RefSeq Acc Id: XP_037865067   ⟸   XM_038009139
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R621 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037865068   ⟸   XM_038009140
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000007798 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000005844.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.640 UniProtKB/TrEMBL
InterPro Arrestin_C UniProtKB/TrEMBL
  Vps26-related UniProtKB/TrEMBL
NCBI Gene VPS26A ENTREZGENE
PANTHER PTHR12233 UniProtKB/TrEMBL
  VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26A UniProtKB/TrEMBL
Pfam Vps26 UniProtKB/TrEMBL
UniProt A0A0D9R621 ENTREZGENE, UniProtKB/TrEMBL