SLC37A4 (solute carrier family 37 member 4) - Rat Genome Database

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Gene: SLC37A4 (solute carrier family 37 member 4) Chlorocebus sabaeus
Analyze
Symbol: SLC37A4
Name: solute carrier family 37 member 4
RGD ID: 18501348
Description: ENCODES a protein that exhibits glucose-6-phosphate transmembrane transporter activity (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); glucose homeostasis (ortholog); glucose-6-phosphate transport (ortholog); PARTICIPATES IN electron transport chain pathway; fructose-1,6-bisphosphatase deficiency pathway; gluconeogenesis pathway; ASSOCIATED WITH CD3epsilon deficiency (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); congenital disorder of glycosylation (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glucose-6-phosphate exchanger SLC37A4; glucose-6-phosphate translocase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,396,133 - 110,402,737 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,395,612 - 110,401,358 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604315,631,589 - 15,638,169 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SLC37A4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,396,133 - 110,402,737 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,395,612 - 110,401,358 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604315,631,589 - 15,638,169 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SLC37A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811119,024,112 - 119,030,877 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11119,023,751 - 119,030,906 (-)EnsemblGRCh38hg38GRCh38
GRCh3711118,894,822 - 118,901,587 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,400,274 - 118,406,800 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411118,400,273 - 118,406,629NCBI
Celera11116,053,114 - 116,059,668 (-)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11114,834,720 - 114,841,274 (-)NCBIHuRef
CHM1_111118,781,352 - 118,787,906 (-)NCBICHM1_1
T2T-CHM13v2.011119,044,474 - 119,051,238 (-)NCBIT2T-CHM13v2.0
Slc37a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39944,308,243 - 44,314,263 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl944,308,149 - 44,314,265 (+)EnsemblGRCm39 Ensembl
GRCm38944,396,946 - 44,402,966 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,396,852 - 44,402,968 (+)EnsemblGRCm38mm10GRCm38
MGSCv37944,206,259 - 44,211,049 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36944,149,171 - 44,153,961 (+)NCBIMGSCv36mm8
Celera941,645,753 - 41,650,553 (+)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
Slc37a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8853,619,952 - 53,626,110 (+)NCBIGRCr8
mRatBN7.2844,723,216 - 44,729,301 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl844,723,339 - 44,729,301 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx850,219,432 - 50,225,517 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0848,498,149 - 48,504,234 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,368,147 - 46,374,232 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0848,716,914 - 48,723,024 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl848,716,939 - 48,723,024 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0847,335,891 - 47,341,995 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,363,896 - 47,369,981 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1847,372,661 - 47,378,744 (+)NCBI
Celera844,309,446 - 44,315,531 (+)NCBICelera
Cytogenetic Map8q22NCBI
Slc37a4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541220,133,652 - 20,139,542 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541220,133,652 - 20,140,134 (-)NCBIChiLan1.0ChiLan1.0
SLC37A4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29119,729,117 - 119,736,189 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111120,832,867 - 120,840,028 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011113,862,537 - 113,869,447 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111117,792,700 - 117,799,269 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11117,792,700 - 117,799,269 (-)Ensemblpanpan1.1panPan2
SLC37A4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1514,823,485 - 14,830,007 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl514,823,499 - 14,830,004 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha514,876,420 - 14,882,925 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0514,766,724 - 14,773,278 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl514,766,743 - 14,773,278 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1514,905,007 - 14,911,527 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0514,808,746 - 14,815,273 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0514,849,134 - 14,855,669 (+)NCBIUU_Cfam_GSD_1.0
Slc37a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947101,058,817 - 101,065,693 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365423,980,236 - 3,987,066 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365423,980,538 - 3,987,039 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC37A4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl946,247,284 - 46,254,031 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1946,247,278 - 46,254,068 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2951,282,374 - 51,289,162 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Slc37a4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478414,415,395 - 14,421,944 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478414,415,385 - 14,421,953 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 32
Low 20 28
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000000562   ⟹   ENSCSAP00000015499
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1110,395,612 - 110,401,358 (-)Ensembl
RefSeq Acc Id: XM_008021132   ⟹   XP_008019323
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11110,396,133 - 110,402,737 (-)NCBI
Vero_WHO_p1.0NW_02366604315,631,589 - 15,638,169 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021134   ⟹   XP_008019325
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11110,396,133 - 110,402,518 (-)NCBI
Vero_WHO_p1.0NW_02366604315,631,687 - 15,638,169 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021136   ⟹   XP_008019327
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11110,396,133 - 110,402,518 (-)NCBI
Vero_WHO_p1.0NW_02366604315,631,707 - 15,638,169 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021137   ⟹   XP_008019328
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11110,396,133 - 110,402,684 (-)NCBI
Vero_WHO_p1.0NW_02366604315,631,595 - 15,638,169 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021138   ⟹   XP_008019329
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11110,396,133 - 110,402,519 (-)NCBI
Vero_WHO_p1.0NW_02366604315,631,707 - 15,638,169 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021139   ⟹   XP_008019330
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11110,396,133 - 110,402,684 (-)NCBI
Vero_WHO_p1.0NW_02366604315,631,595 - 15,638,169 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038005102   ⟹   XP_037861030
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604315,631,625 - 15,638,169 (+)NCBI
RefSeq Acc Id: XM_038005103   ⟹   XP_037861031
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604315,631,649 - 15,638,169 (+)NCBI
RefSeq Acc Id: XM_038005104   ⟹   XP_037861032
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604315,631,707 - 15,638,169 (+)NCBI
RefSeq Acc Id: XP_008019323   ⟸   XM_008021132
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S3R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008019330   ⟸   XM_008021139
- Peptide Label: isoform X3
RefSeq Acc Id: XP_008019328   ⟸   XM_008021137
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S3R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008019329   ⟸   XM_008021138
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S3R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008019325   ⟸   XM_008021134
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S3R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008019327   ⟸   XM_008021136
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S3R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000015499   ⟸   ENSCSAT00000000562
RefSeq Acc Id: XP_037861030   ⟸   XM_038005102
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S3R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861031   ⟸   XM_038005103
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037861032   ⟸   XM_038005104
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002544 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000562.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro MFS UniProtKB/TrEMBL
  MFS_dom UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
  Sugar-P_transporter_CS UniProtKB/TrEMBL
  Sugar_P_transporter UniProtKB/TrEMBL
NCBI Gene SLC37A4 ENTREZGENE
PANTHER GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 UniProtKB/TrEMBL
  GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 UniProtKB/TrEMBL
Pfam MFS_1 UniProtKB/TrEMBL
PIRSF Hexose_phosphate_transp UniProtKB/TrEMBL
PROSITE GLPT UniProtKB/TrEMBL
  MFS UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
UniProt A0A0D9S3R0 ENTREZGENE, UniProtKB/TrEMBL