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Gene: PKD2 (polycystin 2, transient receptor potential cation channel) Chlorocebus sabaeus

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Symbol:

PKD2

Name:

polycystin 2, transient receptor potential cation channel

RGD ID:

18501101

Description:

ENCODES a protein that exhibits alpha-actinin binding (ortholog); ATPase binding (ortholog); calcium channel activity (ortholog); INVOLVED IN calcium ion transport (ortholog); cell surface receptor signaling pathway via JAK-STAT (ortholog); cellular response to calcium ion (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); autosomal dominant polycystic kidney disease (ortholog); autosomal recessive polycystic kidney disease (ortholog); FOUND IN cell-cell junction (ortholog); Golgi apparatus (ortholog); microtubule cytoskeleton (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

polycystin-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	36,369,226 - 36,445,713 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	36,369,524 - 36,443,612 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	15,121,642 - 15,193,435 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute kidney failure (ISO)

autosomal dominant polycystic kidney disease (ISO)

autosomal recessive polycystic kidney disease (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

hydrocele (ISO)

intracranial aneurysm (ISO)

Joubert syndrome 7 (ISO)

Kidney Reperfusion Injury (ISO)

neurodegenerative disease (ISO)

oligohydramnios (ISO)

polycystic kidney disease (ISO)

polycystic kidney disease 2 (ISO)

polycystic liver disease (ISO)

polycystic liver disease 1 (ISO)

retinal degeneration (ISO)

retinal disease (ISO)

vascular disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

aorta development (IEA)

branching involved in ureteric bud morphogenesis (IEA)

calcium ion transmembrane transport (IEA)

calcium ion transport (IEA,ISO)

calcium-mediated signaling (IEA)

cell surface receptor signaling pathway (IEA)

cell surface receptor signaling pathway via JAK-STAT (ISO)

cellular response to calcium ion (ISO)

cellular response to cAMP (IEA)

cellular response to fluid shear stress (IEA)

cellular response to hydrostatic pressure (IEA)

cellular response to osmotic stress (IEA)

cilium organization (IEA,ISO)

detection of mechanical stimulus (IEA,ISO)

detection of nodal flow (ISO)

determination of left/right symmetry (ISO)

determination of liver left/right asymmetry (IEA)

embryonic placenta development (ISO)

establishment of localization in cell (ISO)

heart development (IEA,ISO)

heart looping (IEA)

inorganic cation transmembrane transport (IEA)

intracellular calcium ion homeostasis (ISO)

kidney development (ISO)

liver development (IEA,ISO)

mesonephric duct development (IEA)

mesonephric tubule development (IEA)

metanephric ascending thin limb development (IEA)

metanephric cortex development (IEA)

metanephric cortical collecting duct development (IEA)

metanephric distal tubule development (IEA)

metanephric mesenchyme development (IEA)

metanephric part of ureteric bud development (IEA)

metanephric S-shaped body morphogenesis (IEA)

metanephric smooth muscle tissue development (IEA)

negative regulation of G1/S transition of mitotic cell cycle (IEA,ISO)

negative regulation of ryanodine-sensitive calcium-release channel activity (ISO)

neural tube development (IEA)

placenta blood vessel development (ISO)

positive regulation of cytosolic calcium ion concentration (ISO)

positive regulation of gene expression (ISO)

positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (ISO)

positive regulation of nitric oxide biosynthetic process (IEA)

positive regulation of transcription by RNA polymerase II (IEA)

potassium ion transmembrane transport (IEA)

potassium ion transport (ISO)

protein heterotetramerization (IEA)

protein homotetramerization (IEA)

protein tetramerization (IEA)

regulation of calcium ion import (IEA)

regulation of cell cycle (ISO)

regulation of cell population proliferation (IEA)

release of sequestered calcium ion into cytosol (IEA,ISO)

renal artery morphogenesis (IEA)

renal tubule morphogenesis (ISO)

sodium ion transmembrane transport (IEA)

sodium ion transport (ISO)

spinal cord development (IEA)

Wnt signaling pathway (IEA)

Cellular Component

basal cortex (IEA)

basal plasma membrane (IEA)

basolateral plasma membrane (IEA)

cation channel complex (IEA)

cell projection (IEA)

cell-cell junction (ISO)

ciliary basal body (IEA)

ciliary membrane (IEA)

cilium (IEA)

cytoplasm (IEA)

cytoplasmic side of endoplasmic reticulum membrane (IEA)

cytoplasmic vesicle (IEA)

cytoplasmic vesicle membrane (IEA)

cytosol (IEA)

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (IEA)

extracellular exosome (IEA)

Golgi apparatus (ISO)

lamellipodium (IEA)

lumenal side of endoplasmic reticulum membrane (IEA)

membrane (IEA)

microtubule cytoskeleton (ISO)

migrasome (IEA)

mitotic spindle (IEA)

monoatomic ion channel complex (IEA)

motile cilium (ISO)

non-motile cilium (ISO)

plasma membrane (IEA)

polycystin complex (IEA)

spindle microtubule (ISO)

Molecular Function

actinin binding (IEA)

alpha-actinin binding (ISO)

ATPase binding (ISO)

calcium channel activity (IEA,ISO)

calcium ion binding (IEA)

calcium-induced calcium release activity (IEA)

channel activity (ISO)

cytoskeletal protein binding (IEA)

HLH domain binding (IEA)

identical protein binding (IEA)

metal ion binding (IEA)

monoatomic cation channel activity (IEA)

muscle alpha-actinin binding (IEA,ISO)

outward rectifier potassium channel activity (ISO)

phosphoprotein binding (IEA)

potassium channel activity (IEA)

protein binding (ISO)

protein homodimerization activity (IEA)

signaling receptor binding (IEA)

sodium channel activity (ISO)

transcription regulator inhibitor activity (IEA)

transmembrane transporter binding (IEA)

voltage-gated calcium channel activity (IEA)

voltage-gated monoatomic cation channel activity (IEA)

voltage-gated monoatomic ion channel activity (IEA)

voltage-gated potassium channel activity (IEA)

voltage-gated sodium channel activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

PKD2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	36,369,226 - 36,445,713 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	36,369,524 - 36,443,612 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	15,121,642 - 15,193,435 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

PKD2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	88,007,635 - 88,077,777 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	88,007,635 - 88,077,777 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	88,928,787 - 88,998,929 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	89,147,844 - 89,217,953 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	89,285,998 - 89,356,107	NCBI
Celera	4	86,220,746 - 86,290,863 (+)	NCBI		Celera
Cytogenetic Map	4	q22.1	NCBI
HuRef	4	84,675,256 - 84,745,398 (+)	NCBI		HuRef
CHM1_1	4	88,905,594 - 88,975,728 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	91,334,123 - 91,404,269 (+)	NCBI		T2T-CHM13v2.0

Pkd2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	104,599,379 - 104,653,685 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	104,607,316 - 104,653,685 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	104,453,982 - 104,505,819 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	104,459,450 - 104,505,819 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	104,888,476 - 104,934,838 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	104,699,856 - 104,746,118 (+)	NCBI		MGSCv36	mm8
Celera	5	101,769,092 - 101,817,838 (+)	NCBI		Celera
Cytogenetic Map	5	E5	NCBI
cM Map	5	50.68	NCBI

Pkd2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	5,541,821 - 5,585,140 (-)	NCBI		GRCr8
mRatBN7.2	14	5,237,135 - 5,280,455 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	5,237,135 - 5,280,825 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	5,198,260 - 5,241,484 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	6,498,456 - 6,541,680 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	5,192,618 - 5,233,125 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	6,602,004 - 6,645,257 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	6,602,004 - 6,645,257 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	6,581,342 - 6,624,595 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	6,349,519 - 6,392,988 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	14	5,376,651 - 5,418,198 (-)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

Pkd2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955474	1,833,701 - 1,868,817 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955474	1,831,221 - 1,868,170 (-)	NCBI	ChiLan1.0	ChiLan1.0

PKD2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	86,009,202 - 86,079,254 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	86,271,612 - 86,341,660 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	80,295,243 - 80,365,271 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	91,019,739 - 91,088,858 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	91,019,734 - 91,086,775 (+)	Ensembl	panpan1.1		panPan2

PKD2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	11,383,441 - 11,437,603 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	11,383,424 - 11,435,438 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	30,517,045 - 30,571,324 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	11,435,888 - 11,490,399 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	11,435,683 - 11,490,397 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	11,519,719 - 11,571,825 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	11,345,806 - 11,399,834 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	28,555,188 - 28,609,469 (-)	NCBI		UU_Cfam_GSD_1.0

Pkd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	1,657,007 - 1,709,229 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936905	76,781 - 128,995 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PKD2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	131,005,407 - 131,058,932 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	131,002,973 - 131,058,932 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	140,233,075 - 140,289,084 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Pkd2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624872	4,539,847 - 4,594,793 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624872	4,539,965 - 4,592,004 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in PKD2
1596 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007999207	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037989839	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037989840	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000002335 ⟹ ENSCSAP00000000651

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	7	36,369,524 - 36,443,612 (+)	Ensembl

RefSeq Acc Id:

XM_007999207 ⟹ XP_007997398

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	7	36,369,226 - 36,445,713 (+)	NCBI
Vero_WHO_p1.0	NW_023666037	15,121,856 - 15,193,435 (+)	NCBI

Sequence:

show sequence

CAGGAGGCGGCGGGCGCCGCAAAGAAAGGAACATGGCTCCTGAGGCGCATAGCGCCGAGAGCGG
CGCCGGGCACCCGTGCGCCGGACGCCAGTGACCGCGATGGTGAACTCCAGCCGCGTGCAGCCTC
AGCAGCCCGGGGACGCCAAGCGGCCGCCCGCGCCCCGCGCGCCGGACCCGGGCCGGCTGATGGC
GGGCTGCGCGGCCGTGGGCGCCAGCCTCGCCGCCCCCGGCGGCCTCCGCGACCAGCGGGGCCTG
GAGATCGAGATGCAGCGCATCCGGCAGGCGGCTGCGCGGGACCCCCCGGCCGGAGCTTCGGCCT
CCCCTTCTCCTCCGCTCTCGTCGTGCTCCCGGCAGGCGTGGAGCCGCGATAACCCCGGCTTCGA
GGCCGAGGAGGAGGAGGAGGAGGAGGTGGAAGGGGAAGAAGGCGGAATGGTGGTGGAGATGGAC
GTAGAGTGGCGCCCGGGCAGCCGGAGGTCGGCGGCCTCCTCGGCCGTGAGCTCCGCAGGCGCGC
GGGGCCGGGGGCTTGGGGGCTACCACAGCGCGGGCCACCCGAGCGGGAGGCGGCGCCGGCGAGA
GGACCAGGGCCCGCCGTGCCCCAGCTCGGCCGGCGGTGGGGACCCGCTGCATCGCCACCTCCCC
CTGGACGGGCAGGCGCCCCGAGTGGCCTGGGCGGAGAGGCTGGTTCGCGGGCTGCGAGGTCTCT
GGGGAACAAGACTCATGGAGGAAAGCAGCACTAACCGAGAGAAATACCTTAAAAGTGTTTTACG
GGAACTGGTCACATACCTCCTTTTTCTCATAGTCTTGTGCATCTTGACCTACGGCATGATGAGC
TCCAATGTGTACTACTACACCCGGATGATGTCACAGCTCTTCCTAGACACCCCCGTGTCCAAAA
CAGAGAAAACTAACTTTAAAACTCTGTCTTCCATGGAAGACTTCTGGAAGTTCACAGAAGGCTC
CTTATTGGATGGGCTGTACTGGAAGATGCAGCCCAGTAACCAGACTGAAGCTGACAACCGAAGT
TTCATCTTCTATGAGAACCTGTTGTTAGGGGTACCACGAATACGGCAACTCCGAGTCAGAAATG
GATCCTGCTCTATCCCCCAGGACTTGAGAGATGAAATTAAAGAGTGCTATGATGTCTACTCTGT
CAGTAGTGAAGATAGGGCTCCCTTCGGGCCCCGAAATGGAACCGCTTGGATCTACACAAGTGAA
AAAGACTTGAATGGTAGTAGCCACTGGGGAATCATTGCAACTTATAGTGGAGCTGGCTATTATC
TGGATTTGTCAAGAACAAGAGAGGAAACAGCTGCACAAGTTGCTAGCCTCAAGAAAAATGTCTG
GCTGGACCGAGGAACCAGGGCAACTTTTATTGACTTCTCAGTGTACAACGCCAACATTAACCTG
TTCTGTGTGGTCAGGTTATTGGTTGAATTCCCAGCAACAGGCGGTGTGATTCCATCTTGGCAAT
TTCAGCCTTTAAAGCTGATCCGATATGTCACAACTTTTGATTTCTTCCTGGCAGCCTGTGAGAT
TATCTTTTGTTTCTTTATCCTTTACTACGTGGTGGAAGAGATATTGGAAATTCGCATTCACAAA
CTACACTATTTCAGGAGTTTCTGGAATTGTCTGGATGTTGTGATCGTTGTGCTATCAGTGGTAG
CTATAGGAATTAGCATATACAGAACATCAAATGTGGAGGTGCTCTTACAGTTTCTGGAAGATCA
AAATACTTTCCCCAACTTTGAGCATCTGGCATATTGGCAAATACAGTTCAACAATATAGCTGCT
GTCACAGTATTTTTTGTCTGGATTAAGCTCTTCAAATTCATCAATTTTAACAGGACCATGAGCC
AGCTCTCGACAACCATGTCTCGATGTGCCAAAGACCTGTTTGGCTTTGCTATTATGTTCTTCAT
TATTTTCCTAGCATATGCTCAGTTGGCATACCTTGTCTTTGGCACTCAGGTCGATGACTTCAGT
ACTTTCCAAGAGTGTATCTTCACTCAATTCCGTATCATTTTGGGCGATATCAACTTTGCAGAGA
TTGAGGAAGCTAATCGAGTTTTGGGACCAATTTATTTCACTACATTTGTGTTCTTTATGTTCTT
CATTCTTTTGAATATGTTTTTGGCTATCATCAATGATACTTACTCTGAAGTGAAATCTGACTTG
GCACAGCAGAAAGCTGAAATGGAACTCTCAGATCTTATCAGAAAGGGCTACCATAAAGCTTTGG
TCAAACTAAAACTGAAAAAAAACACTGTGGATGACATTTCAGAGAGTCTGCGGCAAGGGGGAGG
CAAGTTAAACTTTGACGAACTTCGACAAGATCTCAAAGGGAAGGGCCATACTGATGCAGAGATT
GAGGCAATATTCACAAAGTACGACCAAGATGGAGACCAAGAACTGACCGAACATGAACATCAGC
AGATGAGAGACGACTTGGAGAAAGAGAGGGAGGATCTGGATTTGGATCACAGTTCTTTACCACG
TCCCATGAGCAGCCGAAGTTTCCCTCGAAGCCTGGATGACTCTGAGGAGGATGATGATGAAGAC
AGCGGACATAGCTCCAGAAGGAGGGGAAGCATTTCTAGTGGCGTTTCTTATGAAGAGTTTCAAG
TCCTGGTGAGACGAGTGGACCGGATGGAGCATTCCATCGGCAGCATAGTGTCCAAGATCGACGC
TGTGATCGTGAAGCTGGAGATTATGGAGCGAGCCAAACTGAAGAGGAGGGAGGTGCTGGGAAGG
CTGCTGGATGGGGTGGCCGAGGATGAAAGGCTGGGTCGTGACAGTGAAATCCACAGGGAACAGA
TGGAACGGCTAGTGCGTGAAGAGTTGGAACGCTGGGAATCCGATGATGCAGCTTCCCAGATCAG
TCATGGTTTAGGCACGCCAGTGGGACTAAATGGTCAACCTCGCCCCAGAAGCTCCCGCCCGTCT
TCCTCCCAGTCTACCGAAGGCATGGAAGGTGCAGGTGGAAATGGGAGTTCTAATGTCCACGTAT
GATATGTGTGTGTTAGTATGTGTGTTTCTAATAAGTGAGGAAGCGGCTGTCCTGAGTTGCTGTA
ACAAGCACAGTATTTATATGCCCTGACCACCACAGGATGCAAGTCTTTGTGACTGATTGCTAAC
CTTCTGCACTTTAATTTATTTTATATAAACTTTACCCATGGTTCAAAGGTTTTTTTTCTTTTTC
TCATATAAGAAATCTAGGTGTAAATATCGAGTACAGAAAAAAAAATCTTCGTGAAGTGTATTGA
GTGGTACGCCCAGTTGCCACCATGCCTGAGTCTTCTCAGTTGACAATGAAGTAGCCTTTTAAAG
CTAGAAAATCGTCAAAGGGCTTCTGAGTTTCATTTCCAGTCACAAAAATCAGTATTGTTATTTT
TTTCCAAGTGTGTGAAGGAGAATGGGGCATTCCTTTCCACTCTGGCTTAGTTCATGAGCTTAAT
ACATAGTTTTCTTTTAAGAAAGGAGCCTTTTATTTCAACTACCTTCCTGGGGTAAACTTTTCTA
AAAGATAAAATGGAACAGAACTCCAAATCATAGAATGGGTATGTAGTCATTAATAGAATCTGTG
TGAATGGTTAAGATGAATGTTAAATACTATGCTTTTTTGTAAGTTTATCATATCTGATGTCTGT
GGGACTACCTGTATCACTTAATTTTTAAATTATTTTGGCTCTAATTTGAATAAGCTGAGTAAAG
CCACCAAAGGTCAGTTATAGGATAAAATGGCATCTCTAACCATAACACAGGAGAATTGGAGGGA
GCCCTAAGTTGTCACTATGTTTAATTTCTTTTAATGGTTAGTTTAGCATAAAGATTGATCTACA
TGTTCTTTTTCCCATGTGGCTCTACTCATTTGCAACTGAATTTAATGTTATAACGAATCTAGTA
GGAACAAGTTACTAAATTTTTAGTATGCACTGAAAGTTTTAATTCAACAATTATGTTCATTTTA
AGCAAAATCTTAAGAAAGTTTTGAAATCCATAAAGCATTTGGTTTTAAACTATTTTAAGAATAT
AGTACTCAGTCAGGTATGACAGCTCACACCTGTAATCCCAGCCCTTTGGGAGGCCGAGGCAGGC
GAATCACTTGAGCCCAGGAGTTCAAGACCAACGTGGGTAATGTGGTGAAACCCCATCTCTACAA
AAAATGCAAAAATAAAAAATACAGTACTCAAGTATTCTTGATCCTGTGTTTCAAAACTAGAATG
TATAATCCAAATGGAGCTCAATCTAATAAGAAAGAGATTTTGGTATTGAAAGTTCATACATTAG
ACAGTATCAGCCAAAATTTGAGTTAGCAACACTGTTTTCTTTACGAGAGGGTTTCACCCAAATT
TATGGGGAGAAATCTGTTTCTCAAAAAGAAAATCTTTTACAGAAATGTTGAGTAAGGTGACATT
TTGAGAGCTAATAAGCAAAAGAGCATGCAGTGGTGTTGAATAACCCTCACTTGGAGAACCAAGA
GAATCCTGTCGTTTAATGCTATATTTTAAATTCACAAGTTGTTCATTTAACTAGTAGAATGTCA
GTCCAATCTCCAATGAGAACATGAGCAAATAGGCCTTTCCAGTTTGAAAGTGAAACATACTGGG
TTTCTGTTAAGTTTTTTCCTCATGGCTTCATCTCTATCTTTACTTTCTCTTGAATATGCTACAC
AAAGTTCTTTATTACTACATACTAAAGTTTGCATTCCAGGGATATTGACTGTACATATTTATGT
ATATGTACCATGTTGTTACATGTAAACAAACTTCAATTTGAAGTGCAGCTATTATGTGGTATCC
ATGTGTATCGACCGTGTGCCATATATCAATTATGGTCACTAGAAAGTCTTTTAATGATACCTTT
ATTATACCGTTTTTCATTTCACTTGCAAAATTTCACAGAATTCCTCCTTTCTACCCATAAATTA
CATATATTTTTCTTCTTTAGTCATGGAGAATTCCCCCCTCATCTCTTCCCTATTATCTTTCCCT
GTGTACTGGTATTATTAAAAAGATGTTACATATGCAAGTCTTTCTCGACAATCAAGAATGTTAT
TAATGTGTAATACTGAGCACTTTACTTCTTAATAAAAACTTGATATAGTAGCAGA

hide sequence

RefSeq Acc Id:

XM_037989839 ⟹ XP_037845767

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666037	15,121,842 - 15,193,435 (+)	NCBI

RefSeq Acc Id:

XM_037989840 ⟹ XP_037845768

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666037	15,121,642 - 15,193,435 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_007997398	(Get FASTA)	NCBI Sequence Viewer
	XP_037845767	(Get FASTA)	NCBI Sequence Viewer
	XP_037845768	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000000651
	ENSCSAP00000000651.1

RefSeq Acc Id:	XP_007997398 ⟸ XM_007999207
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9QWB2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000000651 ⟸ ENSCSAT00000002335

RefSeq Acc Id:	XP_037845768 ⟸ XM_037989840
- Peptide Label:	isoform X3
- UniProtKB:	A0A0D9QWB2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_037845767 ⟸ XM_037989839
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9QWB2 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000004305	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000002335.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.70	UniProtKB/TrEMBL
	1.20.120.350	UniProtKB/TrEMBL
	1.20.5.340	UniProtKB/TrEMBL
	EF-hand	UniProtKB/TrEMBL
InterPro	EF-hand-dom_pair	UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/TrEMBL
	PKD1_2_channel	UniProtKB/TrEMBL
	PKD_2	UniProtKB/TrEMBL
	Polycystin	UniProtKB/TrEMBL
	Polycystin_dom	UniProtKB/TrEMBL
	Volt_channel_dom_sf	UniProtKB/TrEMBL
NCBI Gene	PKD2	ENTREZGENE
PANTHER	POLYCYSTIN FAMILY MEMBER	UniProtKB/TrEMBL
	POLYCYSTIN-2	UniProtKB/TrEMBL
Pfam	Fer4_24	UniProtKB/TrEMBL
	PKD_channel	UniProtKB/TrEMBL
	Polycystin_dom	UniProtKB/TrEMBL
PRINTS	POLYCYSTIN2	UniProtKB/TrEMBL
PROSITE	EF_HAND_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/TrEMBL
	Voltage-gated potassium channels	UniProtKB/TrEMBL
UniProt	A0A0D9QWB2	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM