NDUFB6 (NADH:ubiquinone oxidoreductase subunit B6) - Rat Genome Database

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Gene: NDUFB6 (NADH:ubiquinone oxidoreductase subunit B6) Chlorocebus sabaeus
Analyze
Symbol: NDUFB6
Name: NADH:ubiquinone oxidoreductase subunit B6
RGD ID: 18499825
Description: INVOLVED IN mitochondrial respiratory chain complex I assembly (ortholog); ASSOCIATED WITH acromesomelic dysplasia, Maroteaux type (ortholog); distal arthrogryposis type 1A (ortholog); frontotemporal dementia and/or amyotrophic lateral sclerosis 6 (ortholog); FOUND IN mitochondrial membrane (ortholog); mitochondrial respiratory chain complex I (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11247,682,066 - 47,701,467 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1247,682,192 - 47,701,273 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603844,574,190 - 44,593,784 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NDUFB6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11247,682,066 - 47,701,467 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1247,682,192 - 47,701,273 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603844,574,190 - 44,593,784 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
NDUFB6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38932,553,001 - 32,573,159 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl932,553,001 - 32,573,184 (-)EnsemblGRCh38hg38GRCh38
GRCh37932,552,999 - 32,573,157 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36932,543,523 - 32,563,182 (-)NCBINCBI36Build 36hg18NCBI36
Build 34932,543,522 - 32,563,182NCBI
Celera932,484,729 - 32,504,395 (-)NCBICelera
Cytogenetic Map9p21.1NCBI
HuRef932,510,306 - 32,529,979 (-)NCBIHuRef
CHM1_1932,553,559 - 32,573,243 (-)NCBICHM1_1
T2T-CHM13v2.0932,569,166 - 32,589,354 (-)NCBIT2T-CHM13v2.0
Ndufb6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39440,270,591 - 40,279,421 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl440,270,591 - 40,279,421 (-)EnsemblGRCm39 Ensembl
GRCm38440,270,591 - 40,279,421 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl440,270,591 - 40,279,421 (-)EnsemblGRCm38mm10GRCm38
MGSCv37440,217,696 - 40,226,401 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36440,459,334 - 40,468,039 (-)NCBIMGSCv36mm8
Celera439,933,667 - 39,942,372 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map420.24NCBI
Ndufb6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8560,196,585 - 60,206,152 (-)NCBIGRCr8
mRatBN7.2555,400,543 - 55,410,110 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl555,400,543 - 55,410,181 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx557,366,430 - 57,376,013 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0559,185,572 - 59,195,154 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0559,157,294 - 59,166,874 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0556,567,109 - 56,576,676 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl556,567,109 - 56,576,676 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0561,110,999 - 61,120,566 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4557,677,225 - 57,687,302 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1557,677,435 - 57,687,478 (-)NCBI
Celera554,016,558 - 54,026,125 (-)NCBICelera
Cytogenetic Map5q22NCBI
Ndufb6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554723,054,154 - 3,064,433 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554723,054,026 - 3,064,530 (+)NCBIChiLan1.0ChiLan1.0
NDUFB6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21192,039,523 - 92,061,250 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1992,045,465 - 92,067,192 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0932,327,973 - 32,347,518 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1933,137,836 - 33,157,006 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl933,137,836 - 33,157,006 (-)Ensemblpanpan1.1panPan2
NDUFB6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11149,821,998 - 49,833,624 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl223,526,115 - 3,526,501 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1148,444,163 - 48,455,988 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01150,762,716 - 50,774,556 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1150,762,715 - 50,774,556 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11149,425,777 - 49,437,612 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01149,292,319 - 49,304,367 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01150,051,004 - 50,062,839 (-)NCBIUU_Cfam_GSD_1.0
Ndufb6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947164,684,163 - 164,696,201 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365241,231,852 - 1,243,659 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365241,231,744 - 1,243,783 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFB6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1033,802,051 - 33,865,385 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11033,849,206 - 33,865,080 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21038,102,584 - 38,118,493 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Ndufb6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473637,223,153 - 37,235,027 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473637,223,046 - 37,235,144 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 17 60
Low 3
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007969028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000007933   ⟹   ENSCSAP00000006092
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1247,682,192 - 47,701,273 (+)Ensembl
RefSeq Acc Id: XM_007969028   ⟹   XP_007967219
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11247,682,066 - 47,701,467 (+)NCBI
Vero_WHO_p1.0NW_02366603844,574,190 - 44,593,784 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007967219 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000006092.1
Reference Protein Sequences
RefSeq Acc Id: XP_007967219   ⟸   XM_007969028
- UniProtKB: A0A0D9RBV3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000006092   ⟸   ENSCSAT00000007933


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000009865 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000007933.1 UniProtKB/TrEMBL
InterPro NADH_DH_b-subcmplx_su6 UniProtKB/TrEMBL
KEGG Report csab:103219306 UniProtKB/TrEMBL
NCBI Gene NDUFB6 ENTREZGENE
PANTHER NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 UniProtKB/TrEMBL
  PTHR15083 UniProtKB/TrEMBL
Pfam NDUF_B6 UniProtKB/TrEMBL
UniProt A0A0D9RBV3 ENTREZGENE, UniProtKB/TrEMBL