ZHX2 (zinc fingers and homeoboxes 2) - Rat Genome Database

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Gene: ZHX2 (zinc fingers and homeoboxes 2) Chlorocebus sabaeus
Analyze
Symbol: ZHX2
Name: zinc fingers and homeoboxes 2
RGD ID: 18499318
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); identical protein binding (inferred); INVOLVED IN mRNA catabolic process (ortholog); negative regulation of neuron differentiation (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH genetic disease (ortholog); Hirschsprung's disease (ortholog); trichorhinophalangeal syndrome type I (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc fingers and homeoboxes protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18117,360,134 - 117,550,818 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8117,531,654 - 117,534,167 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603922,683,909 - 22,875,372 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA,ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ZHX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18117,360,134 - 117,550,818 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8117,531,654 - 117,534,167 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603922,683,909 - 22,875,372 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ZHX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388122,780,379 - 122,974,510 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8122,781,655 - 122,974,510 (+)EnsemblGRCh38hg38GRCh38
GRCh378123,793,894 - 123,986,750 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368123,863,082 - 124,055,936 (+)NCBINCBI36Build 36hg18NCBI36
Build 348123,863,169 - 124,055,929NCBI
Celera8119,982,978 - 120,175,825 (+)NCBICelera
Cytogenetic Map8q24.13NCBI
HuRef8119,119,533 - 119,312,420 (+)NCBIHuRef
CHM1_18123,834,160 - 124,026,965 (+)NCBICHM1_1
T2T-CHM13v2.08123,911,550 - 124,105,660 (+)NCBIT2T-CHM13v2.0
Zhx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391557,558,063 - 57,703,228 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1557,558,061 - 57,703,228 (+)EnsemblGRCm39 Ensembl
GRCm381557,694,667 - 57,839,832 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1557,694,665 - 57,839,832 (+)EnsemblGRCm38mm10GRCm38
MGSCv371557,526,222 - 57,671,387 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361557,524,854 - 57,669,854 (+)NCBIMGSCv36mm8
Celera1559,214,205 - 59,360,402 (+)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1524.01NCBI
Zhx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8791,115,894 - 91,263,823 (+)NCBIGRCr8
mRatBN7.2789,226,358 - 89,374,266 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl789,226,463 - 89,374,378 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx791,104,191 - 91,239,446 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0793,305,463 - 93,440,722 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0793,117,212 - 93,252,387 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0797,559,653 - 97,707,872 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl797,559,841 - 97,695,739 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0798,166,854 - 98,314,735 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4794,528,435 - 94,530,945 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1794,563,246 - 94,563,739 (+)NCBI
Celera786,000,415 - 86,135,018 (+)NCBICelera
Cytogenetic Map7q33NCBI
Zhx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555401,805,666 - 1,890,409 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555401,805,648 - 1,890,409 (+)NCBIChiLan1.0ChiLan1.0
ZHX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27140,210,065 - 140,403,883 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18115,722,800 - 115,916,584 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08119,473,607 - 119,668,790 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18122,306,315 - 122,424,518 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8122,401,567 - 122,404,080 (+)Ensemblpanpan1.1panPan2
ZHX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11321,231,985 - 21,393,756 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1321,377,316 - 21,379,832 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1321,342,934 - 21,359,598 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01321,568,837 - 21,730,547 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1321,569,100 - 21,730,552 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11321,297,771 - 21,459,250 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01321,402,546 - 21,564,353 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01321,645,278 - 21,807,009 (+)NCBIUU_Cfam_GSD_1.0
Zhx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530316,889,272 - 17,048,441 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647024,315,404 - 24,474,282 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647024,315,371 - 24,476,063 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZHX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl416,374,902 - 16,553,002 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1416,374,900 - 16,553,859 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2417,144,095 - 17,315,274 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Zhx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473531,882,434 - 32,013,773 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 35 21
Low 1 20 39
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000018703   ⟹   ENSCSAP00000018146
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl8117,531,654 - 117,534,167 (+)Ensembl
RefSeq Acc Id: XM_008001455   ⟹   XP_007999646
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.18117,360,134 - 117,550,817 (+)NCBI
Vero_WHO_p1.0NW_02366603922,683,909 - 22,875,372 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008001457   ⟹   XP_007999648
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.18117,360,412 - 117,550,817 (+)NCBI
Vero_WHO_p1.0NW_02366603922,683,909 - 22,875,372 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038000184   ⟹   XP_037856112
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603922,683,909 - 22,875,372 (-)NCBI
RefSeq Acc Id: XM_038000185   ⟹   XP_037856113
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603922,683,909 - 22,875,372 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007999646 (Get FASTA)   NCBI Sequence Viewer  
  XP_007999648 (Get FASTA)   NCBI Sequence Viewer  
  XP_037856112 (Get FASTA)   NCBI Sequence Viewer  
  XP_037856113 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000018146
  ENSCSAP00000018146.1
Reference Protein Sequences
RefSeq Acc Id: XP_007999646   ⟸   XM_008001455
- UniProtKB: A0A0D9SBA7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007999648   ⟸   XM_008001457
- UniProtKB: A0A0D9SBA7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000018146   ⟸   ENSCSAT00000018703
RefSeq Acc Id: XP_037856112   ⟸   XM_038000184
- UniProtKB: A0A0D9SBA7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037856113   ⟸   XM_038000185
- UniProtKB: A0A0D9SBA7 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018613 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000018703.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  ZHX_Znf_C2H2 UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
KEGG Report csab:103237373 UniProtKB/TrEMBL
NCBI Gene ZHX2 ENTREZGENE
PANTHER ZINC FINGERS AND HOMEOBOXES PROTEIN 2 UniProtKB/TrEMBL
  ZINC-FINGERS AND HOMEOBOXES RELATED UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
  zf_C2H2_ZHX UniProtKB/TrEMBL
PROSITE HOMEOBOX_2 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A0D9SBA7 ENTREZGENE, UniProtKB/TrEMBL