PSMD12 (proteasome 26S subunit, non-ATPase 12)

Gene: PSMD12 (proteasome 26S subunit, non-ATPase 12) Chlorocebus sabaeus

Analyze

Symbol:

PSMD12

Name:

proteasome 26S subunit, non-ATPase 12

RGD ID:

18492956

Description:

ASSOCIATED WITH contact dermatitis (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); proteasome accessory complex (inferred); proteasome complex (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

26S proteasome non-ATPase regulatory subunit 12

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	54,096,908 - 54,122,164 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	54,096,891 - 54,123,139 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	25,107,288 - 25,132,559 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

contact dermatitis (ISO)

Developmental Disabilities (ISO)

genetic disease (ISO)

intellectual disability (ISO)

Neurodevelopmental Disorders (ISO)

spermatogenic failure 18 (ISO)

Stankiewicz-Isidor Syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasm (IEA)

proteasome accessory complex (IEA)

proteasome complex (IEA)

proteasome regulatory particle (IEA)

proteasome regulatory particle, lid subcomplex (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

PSMD12
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	54,096,908 - 54,122,164 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	54,096,891 - 54,123,139 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	25,107,288 - 25,132,559 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

PSMD12
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	67,337,916 - 67,366,577 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	67,337,916 - 67,366,605 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	65,334,032 - 65,362,693 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	62,767,081 - 62,793,183 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	62,764,494 - 62,793,183	NCBI
Celera	17	61,909,217 - 61,935,322 (-)	NCBI		Celera
Cytogenetic Map	17	q24.2	NCBI
HuRef	17	60,723,677 - 60,749,765 (-)	NCBI		HuRef
CHM1_1	17	65,400,576 - 65,426,678 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	68,213,821 - 68,242,480 (-)	NCBI		T2T-CHM13v2.0

Psmd12
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	107,370,354 - 107,388,862 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	107,370,310 - 107,395,188 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	107,479,528 - 107,498,036 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	107,479,484 - 107,504,362 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	107,340,842 - 107,359,350 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	107,295,618 - 107,314,126 (+)	NCBI		MGSCv36	mm8
Celera	11	119,213,718 - 119,232,238 (+)	NCBI		Celera
Cytogenetic Map	11	E1	NCBI
cM Map	11	70.29	NCBI

Psmd12
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	92,937,957 - 92,956,601 (+)	NCBI		GRCr8
mRatBN7.2	10	92,438,223 - 92,457,323 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	92,438,298 - 92,457,287 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	97,496,377 - 97,515,021 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	96,959,397 - 96,978,042 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	92,361,004 - 92,379,705 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	95,706,808 - 95,725,452 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	95,706,685 - 95,725,812 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	95,441,589 - 95,460,233 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	96,881,373 - 96,907,258 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	96,895,742 - 96,921,629 (+)	NCBI
Celera	10	91,103,741 - 91,122,382 (+)	NCBI		Celera
Cytogenetic Map	10	q32.1	NCBI

Psmd12
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955478	6,535,694 - 6,558,156 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955478	6,536,207 - 6,558,156 (-)	NCBI	ChiLan1.0	ChiLan1.0

PSMD12
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	83,368,845 - 83,393,491 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	88,186,200 - 88,214,591 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	61,273,687 - 61,302,062 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	66,477,716 - 66,505,817 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	66,479,478 - 66,505,817 (-)	Ensembl	panpan1.1		panPan2

PSMD12
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	13,136,883 - 13,170,544 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	13,136,832 - 13,170,147 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	14,030,779 - 14,066,155 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	14,797,042 - 14,832,573 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	14,797,085 - 14,832,806 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	13,746,700 - 13,782,148 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	13,752,964 - 13,788,312 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	13,754,296 - 13,789,691 (-)	NCBI		UU_Cfam_GSD_1.0

Psmd12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	13,409,801 - 13,437,380 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936541	5,757,170 - 5,787,560 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936541	5,757,223 - 5,784,797 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PSMD12
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	13,705,343 - 13,742,776 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	13,704,112 - 13,730,072 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	14,069,036 - 14,095,588 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Psmd12
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624870	1,057,172 - 1,087,955 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624870	1,057,652 - 1,083,844 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	36		59
Low		20	1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008012023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008012024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037993767	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000002192 ⟹ ENSCSAP00000000520

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	16	54,096,891 - 54,123,139 (+)	Ensembl

RefSeq Acc Id:

XM_008012024 ⟹ XP_008010215

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	16	54,102,189 - 54,119,576 (+)	NCBI
Vero_WHO_p1.0	NW_023666077	25,107,326 - 25,132,559 (+)	NCBI

Sequence:

show sequence

GTTGTGTAACAAATCATTAAAAGATTGGATTCATTCAGGAATTAAAGGAGGCGCAAACAGAACT
TACAGATACTCAACATGTATTGATGTTGAACAAACTCATTAGTCGCTTACATCATTTACAAGGA
TTATTTTCATGAGAAAAATGAGTCACGGAAGTCACATGTTCTAACAGGAAGGAAGACTTCAAGA
AGTCATTGAAACCCTTCTCTCTCTGGAAAAGCAGACTCGTACTGCTTCCGATATGGTATCTACA
TCCCGTATCTTAGTTGCAGTAGTGAAGATGTGCTATGAGGCTAAAGAATGGGATTTACTTAATG
AAAACATTATGCTTTTGTCCAAAAGGCGGAGTCAGTTAAAACAGGCTGTTGCCAAAATGGTTCA
ACAGTGCTGTACGTATGTTGAGGAAATCACAGACCTTCCTATCAAACTTCGATTAATTGATACT
CTACGAATGGTTACTGAAGGCAAGATTTATGTTGAAATTGAGCGTGCTCGACTGACTAAAACAT
TAGCAACTATAAAAGAACAAAATGGTGATGTGAAAGAGGCAGCCTCCATTCTACAGGAGTTACA
GGTGGAAACCTACGGGTCAATGGAAAAGAAAGAGAGAGTGGAATTTATTTTGGAGCAAATGAGG
CTCTGCCTAGCTGTGAAGGATTACATTCGAACACAAATCATCAGCAAGAAAATTAACACCAAAT
TTTTCCAGGAAGAAAATACCGAGAAATTAAAGTTGAAGTACTATAATTTAATGATTCAGCTGGA
TCAACATGAGGGATCCTATTTGTCTATTTGTAAGCACTACAGAGCAATATATGATACTCCCTGT
ATACAGGCAGAAAGTGAAAAATGGCAGCAGGCTCTGAAGAGTGTTGTACTCTATGTTATCCTGG
CTCCTTTTGACAACGAACAGTCAGATTTGGTTCACCGAATAAGTGGTGACAAGAAGTTAGAAGA
AATTCCCAAATACAAGGATCTTTTAAAGCTTTTTACCACAATGGAGTTGATGCGTTGGTCCACA
CTTGTTGAGGACTATGGAATGGAATTAAGAAAAGGTTCCCTTGAGAGTCCTGCAACTGATGTTT
TTGGTTCCACGGAGGAAGGCGAAAAAAGGTGGAAAGACTTGAAGAACAGAGTTGTTGAACATAA
TATTAGAATAATGGCCAAGTATTATACTCGGATAACAATGAAAAGGATGGCACAGCTTCTGGAT
CTGTCTGTTGATGAGTCCGAAGCCTTTCTCTCAAATCTAGTAGTTAACAAGACCATCTTTGCTA
AAGTAGACAGATTAGCAGGAATTATCAACTTCCAGAGACCTAAGGATCCAAATAATTTATTAAA
TGACTGGTCTCAGAAACTGAACTCATTAATGTCTCTGGTTAACAAAACTACACATCTCATAGCC
AAAGAGGAGATGATACATAATCTACAATAAGGGTCTTAATGCTTTTAGAAAAAAGTTAAAATTG
GAAGTCATTAAAAAAGACTGTTATAATGGTGTATATGTTGGGGTTTTTTTTCTAAGCTTCTTTG
TCTTAAATTTTAAAATAGTGAATATGTTTTGAGACTCCCTTTGACCTTTCAGTTCCCCAAGTTC
ATTGTTAACTTTGCATTTGCAATTGGTGCAAAAATACACATTTCTGTCGTCTGAATACACAAAA
AGTTGTGTCATAACTTACCCGGATGTTTTTCTATCATTTGAAACCTTTTTAGCTACTGTTTGTT
TTCATTCAACTAACAAACATATTACAATAATAAAAGCAGTATATACACAT

hide sequence

RefSeq Acc Id:

XM_037993767 ⟹ XP_037849695

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666077	25,107,288 - 25,132,559 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008010215	(Get FASTA)	NCBI Sequence Viewer
	XP_037849695	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000000520.1

RefSeq Acc Id:	XP_008010215 ⟸ XM_008012024
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSCSAP00000000520 ⟸ ENSCSAT00000002192

RefSeq Acc Id:	XP_037849695 ⟸ XM_037993767
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9QVY1 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000004164	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000002192.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
InterPro	PCI_dom	UniProtKB/TrEMBL
	PSMD12/CSN4	UniProtKB/TrEMBL
	RPN5_C	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
KEGG Report	csab:103243162	UniProtKB/TrEMBL
NCBI Gene	PSMD12	ENTREZGENE
PANTHER	PTHR10855	UniProtKB/TrEMBL
	PTHR10855:SF1	UniProtKB/TrEMBL
Pfam	PCI	UniProtKB/TrEMBL
	RPN5_C	UniProtKB/TrEMBL
PROSITE	PCI	UniProtKB/TrEMBL
SMART	PINT	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46785	UniProtKB/TrEMBL
UniProt	A0A0D9QVY1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM