CHRNB4 (cholinergic receptor nicotinic beta 4 subunit)

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Gene: CHRNB4 (cholinergic receptor nicotinic beta 4 subunit) Chlorocebus sabaeus

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Symbol:

CHRNB4

Name:

cholinergic receptor nicotinic beta 4 subunit

RGD ID:

18492883

Description:

ENCODES a protein that exhibits acetylcholine binding (ortholog); heterocyclic compound binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN behavioral response to nicotine (ortholog); locomotory behavior (ortholog); neuronal action potential (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); Bloom syndrome (ortholog); chronic obstructive pulmonary disease (ortholog); FOUND IN acetylcholine-gated channel complex (ortholog); cholinergic synapse (ortholog); postsynaptic specialization membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

neuronal acetylcholine receptor subunit beta-4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	4,700,217 - 4,717,363 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	4,701,321 - 4,719,319 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	137,078,808 - 137,095,082 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amyotrophic lateral sclerosis (ISO)

Bloom syndrome (ISO)

chronic obstructive pulmonary disease (ISO)

cocaine abuse (ISO)

colorectal cancer (ISO)

depressive disorder (ISO)

esophagus squamous cell carcinoma (ISO)

frontotemporal dementia (ISO)

lung adenocarcinoma (ISO)

lung cancer (ISO)

Lung Neoplasms (ISO)

lung non-small cell carcinoma (ISO)

lung small cell carcinoma (ISO)

lung squamous cell carcinoma (ISO)

nicotine dependence (ISO)

oral cavity cancer (ISO)

Tobacco Use Disorder (ISO)

Transplant Rejection (ISO)

withdrawal disorder (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

behavioral response to nicotine (ISO)

chemical synaptic transmission (IEA)

excitatory postsynaptic potential (IEA)

locomotory behavior (ISO)

monoatomic ion transmembrane transport (IEA)

nervous system process (IEA)

neuronal action potential (ISO)

positive regulation of transmission of nerve impulse (ISO)

regulation of membrane potential (IEA,ISO)

regulation of postsynaptic membrane potential (IEA)

regulation of smooth muscle contraction (ISO)

response to nicotine (ISO)

signal transduction (IEA)

smooth muscle contraction (ISO)

synaptic transmission involved in micturition (IEA,ISO)

synaptic transmission, cholinergic (IEA)

Cellular Component

acetylcholine-gated channel complex (IEA,ISO)

cholinergic synapse (ISO)

neuron projection (IEA)

plasma membrane (IEA)

postsynaptic membrane (IEA)

postsynaptic specialization membrane (ISO)

protein-containing complex (ISO)

synapse (IEA)

Molecular Function

acetylcholine binding (ISO)

acetylcholine receptor activity (IEA)

acetylcholine-gated monoatomic cation-selective channel activity (IEA)

heterocyclic compound binding (ISO)

protein binding (ISO)

protein-containing complex binding (ISO)

transmembrane signaling receptor activity (IEA)

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

acetylcholine signaling pathway via nicotinic acetylcholine receptor (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CHRNB4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	4,700,217 - 4,717,363 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	4,701,321 - 4,719,319 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	137,078,808 - 137,095,082 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

CHRNB4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	78,624,111 - 78,661,641 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	78,624,111 - 78,727,754 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	78,916,453 - 78,933,552 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	76,703,691 - 76,720,642 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	76,703,690 - 76,720,642	NCBI
Celera	15	55,852,898 - 55,869,734 (-)	NCBI		Celera
Cytogenetic Map	15	q25.1	NCBI
HuRef	15	55,674,500 - 55,691,566 (-)	NCBI		HuRef
CHM1_1	15	79,035,191 - 79,052,089 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	76,487,585 - 76,519,049 (-)	NCBI		T2T-CHM13v2.0

Chrnb4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	54,935,438 - 54,956,236 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	54,935,438 - 54,956,063 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	55,028,154 - 55,048,953 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	55,028,154 - 55,048,779 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	54,875,963 - 54,896,351 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	54,826,293 - 54,846,681 (-)	NCBI		MGSCv36	mm8
Celera	9	52,271,558 - 52,291,872 (-)	NCBI		Celera
Cytogenetic Map	9	B	NCBI
cM Map	9	29.84	NCBI

Chrnb4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	64,312,644 - 64,333,319 (-)	NCBI		GRCr8
mRatBN7.2	8	55,417,583 - 55,437,027 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	55,418,313 - 55,437,027 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	60,959,884 - 60,978,450 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	59,238,885 - 59,257,451 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	57,103,128 - 57,121,694 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	59,610,489 - 59,629,073 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	59,609,693 - 59,629,133 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	58,192,375 - 58,210,959 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	58,586,961 - 58,605,545 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	58,605,220 - 58,624,659 (-)	NCBI
Celera	8	54,902,516 - 54,921,100 (-)	NCBI		Celera
RH 3.4 Map	8	614.4	RGD
Cytogenetic Map	8	q24	NCBI

Chrnb4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955450	1,013,607 - 1,030,282 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955450	1,013,897 - 1,030,232 (-)	NCBI	ChiLan1.0	ChiLan1.0

CHRNB4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	67,837,116 - 67,880,179 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	72,003,030 - 72,045,815 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	57,552,697 - 57,570,828 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	76,515,683 - 76,532,905 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	76,515,455 - 76,532,712 (-)	Ensembl	panpan1.1		panPan2

CHRNB4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	38,312,537 - 38,327,242 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	38,312,173 - 38,328,341 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	38,273,110 - 38,288,065 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	38,786,382 - 38,801,494 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	38,786,222 - 38,800,419 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	38,477,587 - 38,492,683 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	38,586,959 - 38,602,041 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	39,061,951 - 39,077,068 (+)	NCBI		UU_Cfam_GSD_1.0

Chrnb4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	118,560,402 - 118,577,508 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	36,408,447 - 36,426,021 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	36,408,471 - 36,425,571 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CHRNB4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	7	47,338,819 - 47,359,064 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	52,808,908 - 52,829,172 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Chrnb4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624894	2,305,820 - 2,322,505 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624894	2,305,815 - 2,322,264 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008015701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008015702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000013092 ⟹ ENSCSAP00000011104

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	26	4,701,321 - 4,719,319 (+)	Ensembl

RefSeq Acc Id:

XM_008015701 ⟹ XP_008013892

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	26	4,700,219 - 4,717,363 (+)	NCBI
Vero_WHO_p1.0	NW_023666048	137,078,808 - 137,095,080 (-)	NCBI

Sequence:

show sequence

GCATCCCAAAGGGAGAAATCTGCTCCACTTCAACAGTGTTGTTTTTGAAGACTGTATGACAACA
TGTCAGATTATAGCAACATGGTGTGGGGGGAGCAATATGAAAGCAAGACTGAGAGTCTTGGAGA
TAAGGTGGCAAAGCTGCCTTTTTACAGGTGTCACTCCCTCAGACCCTGCCCTTTCCTGCCTTGT
TCCTCCAGTTGTCAGATTTGCCTGTTAGGGCCCACATGGGAGCAGGTAGGAGGACTGGACTGAG
AGGGAGAGGGAGATGCTGCCAGAGGCCCTTCTGGATCCAGAAATGAGGCAGCAGTTCCAGCCAG
GTCCTGAGGTGGCACCTGTCCCACCACCCGCAAGAGAATGGTACTGATTCCAAAAATGCGTCAA
GGAGAGGGCTAGGAGAGGGATGTGCTTGTTGCCTTGAATCACCTGAGCGGCCTCTGTTCAGCCC
AGATTGGAAGGCCCACGGGGGAGGATGAGGCCAGCCCACTCCAGCCCCATCCCCTCCCTTTTAA
CTCTGCTCCTTCCCCAGCCCCCAAGCTGGGTGAGGGGCCCTGAGCTATTCACCCTCCCAGATTC
CACTCACTTTTCCTAAACGCCCTCCCTGCGAAGTCTGCAAAGAGCAGCGCTCCCTCGTGTCGGC
TCACCCCGCAGTGTCGTTTCTTTCAGCAAACCCCATGCGAATGAACTTGAGATGACTCATTTGC
CTAAAAGCCTCTTCGAGGTGAGGGAAGGCAAAGGCCAAGGACCTCCCGGCTCAAGCACATGCTC
CTTCCCCAACAGTAGAGGGATCCTGCGCTAGCGTCTGCTGCCCTCGAGGGCTCACTCTCCCCAG
CTGTACCAAGGGTGCCCGCACTGTCCTGCCTGCCTTCCTTGGGGGAAGGTTGCGAGGCCCGAGG
AGATCGGGAAGCCAGGTGGCGGGTGGGGTCCAGACCACCCCCGGCGTCGAAGCGGAGCAGCGGG
CCCAGTTCATCCCCAGAGTGGGCGGGACTCCCAGCTGCTGCCCACGCGGGGCTTGGCGGGGTTC
GGCGGGGCGCTCCGCGGGGTCCTAGTGAGCGCCGCTGCGCCAGCAAACCTCCGGGGCCAGGACC
GGCGCTCACTCGACCGCGCGGCTCACGGGTGCCCTGTGACCCCAAAGCGGAGCTCGCAGCGGCT
GCCACCCGGCCCTGCCAGCCATGAGGCATGCGCCTTCCCTGGTCCTTTTCCTCCTGGTCGCCCT
TTGCGGGCGGGGGGACTGCCGCATGGCCAATGCAGAGGAAAAGCTGATGGACGACCTTCTGAAC
AAAACCCGTTACAACAACCTGATCCGCCCAGCCACCAGCTCCTCACAGCTCATCTCCATCAAGC
TGCAGCTCTCCCTGGCCCAGCTTATCAGCGTGAATGAGCGAGAGCAGATCATGACCACCAATGT
CTGGCTGAAACAGGAATGGACTGATTACCGCCTGACCTGGAACAGCTCCCGCTACGAGGGTGTG
AACATCCTGAGGATCCCCGCCAAGCGCATCTGGTTGCCTGACATCGTGCTTTACAACAATGCTG
ACGGGACCTATGAGGTGTCTGTCTACACCAACTTGGTAGTCCGGTCCAACGGCAGGGTCCTGTG
GCTGCCCCCTGCCATCTACAAGAGCGCCTGCAAGATTGAGGTGAAGTACTTTCCCTTCGACCAG
CAGAACTGCACCCTCAAGTTCCGCTCCTGGACCTATGACCACACAGAGATAGACATGGTCCTCA
TGACACCCACAGCCAGCATGGATGACTTTACTCCCAGTGGTGAGTGGGACATAGTGGCCCTCCC
AGGGAGAAGGACAGTGAACCCACAGGACCCCAGCTATGTGGACGTGACTTACGACTTCATCATC
AAGCGCAAGCCTCTGTTCTACACCATCAACCTCATCATCCCCTGCGTGCTCATCACCTCGCTGG
CCATCCTCGTCTTCTACCTGCCGTCCGACTGCGGCGAGAAGATGACGCTGTGCATCTCTGTGCT
GCTGGCGCTCACAGTCTTCCTGCTGCTCATCTCCAAGATCGTGCCACCCACCTCCCTCGATGTG
CCTCTCATTGGCAAGTACCTCATGTTCACCATGGTGCTGGTCACCTTCTCCATCGTCACCAGCG
TCTGTGTGCTCAATGTGCACCACCGCTCACCCAGCACCCACACGATGGCACCCTGGGTCAAGCG
CTGCTTCCTGCACAAGCTGCCTACCTTCCTCTTCATGAAGCGCCCTGGCCCTGACAGCAGCCTG
GCCAGAGCCTTCCCGCCCAGCAAGTCACACGTGACCAAGCCCAAGGCCACCACCACCTCCACCA
GCCCCTCCAAACTCTATGGGAACTCCATGTACTTTGTGAACCCTGCCTCTGCAGCTCCCAAGTC
TCCAGCCGGCTCCAGGGATTTCTGGCTGCGGTCCTCTGGGAGGTTCCGACAGGATGTGCAGGAG
GCATTAGAAGGTGTCAGCTTCATCCCCCAGCACATGAAGAATGACAATGAAGACCAGAGTGTCG
TTGAGGACTGGAAGTACGTGGCTATGGTGGTAGACCGGCTGTTCCTGTGGGTGTTCGTGTTTGT
GTGCGTACTGGGCACTGTTGGGCTCTTCCTACCGCCCCTCTTCCAGACCCACACAGCTTCCGAA
GGGCCCTACGCTGCCCAGCGTGACTGAGGGCCCCCTGGGTTGTGGGATGACAGGATGTGAGTGG
CCGGGTGAGCAGTTTGCTGCTTCCTTCTGGGTTGTGGCTGATGAGGCCCTAAATAAATTGGACC
ACTGGCCATCAACCCCATCAAACCAGCCACAGCCATGGAAGAGGCAAGGATGGGGGCCTGGACT
GTCCTCTCTGAATGCCTTGGAGGGATCCCAGGAAGCCCCAGCAGGAGGGAGCTTCAGACAGTTC
AATTCTGGCCTGTCTTCCTTCCCTGCACCGGGCAATGGGGATAAAGATGATATCATAGCAGCAC
CTA

hide sequence

RefSeq Acc Id:

XM_008015702 ⟹ XP_008013893

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	26	4,700,217 - 4,717,160 (+)	NCBI
Vero_WHO_p1.0	NW_023666048	137,078,808 - 137,095,082 (-)	NCBI

Sequence:

show sequence

AAGCATCCCAAAGGGAGAAATCTGCTCCACTTCAACAGTGTTGTTTTTGAAGACTGTATGACAA
CATGTCAGATTATAGCAACATGGTGTGGGGGGAGCAATATGAAAGCAAGACTGAGAGTCTTGGA
GATAAGGTGGCAAAGCTGCCTTTTTACAGGTGTCACTCCCTCAGACCCTGCCCTTTCCTGCCTT
GTTCCTCCAGTTGTCAGATTTGCCTGTTAGGGCCCACATGGGAGCAGGTAGGAGGACTGGACTG
AGAGGGAGAGGGAGATGCTGCCAGAGGCCCTTCTGGATCCAGAAATGAGGCAGCAGTTCCAGCC
AGGTCCTGAGGTGGCACCTGTCCCACCACCCGCAAGAGAATGGTACTGATTCCAAAAATGCGTC
AAGGAGAGGGCTAGGAGAGGGATGTGCTTGTTGCCTTGAATCACCTGAGCGGCCTCTGTTCAGC
CCAGATTGGAAGGCCCACGGGGGAGGATGAGGCCAGCCCACTCCAGCCCCATCCCCTCCCTTTT
AACTCTGCTCCTTCCCCAGCCCCCAAGCTGGGTGAGGGGCCCTGAGCTATTCACCCTCCCAGAT
TCCACTCACTTTTCCTAAACGCCCTCCCTGCGAAGTCTGCAAAGAGCAGCGCTCCCTCGTGTCG
GCTCACCCCGCAGTGTCGTTTCTTTCAGCAAACCCCATGCGAATGAACTTGAGATGACTCATTT
GCCTAAAAGCCTCTTCGAGGTGAGGGAAGGCAAAGGCCAAGGACCTCCCGGCTCAAGCACATGC
TCCTTCCCCAACAGTAGAGGGATCCTGCGCTAGCGTCTGCTGCCCTCGAGGGCTCACTCTCCCC
AGCTGTACCAAGGGTGCCCGCACTGTCCTGCCTGCCTTCCTTGGGGGAAGGTTGCGAGGCCCGA
GGAGATCGGGAAGCCAGGTGGCGGGTGGGGTCCAGACCACCCCCGGCGTCGAAGCGGAGCAGCG
GGCCCAGTTCATCCCCAGAGTGGGCGGGACTCCCAGCTGCTGCCCACGCGGGGCTTGGCGGGGT
TCGGCGGGGCGCTCCGCGGGGTCCTAGTGAGCGCCGCTGCGCCAGCAAACCTCCGGGGCCAGGA
CCGGCGCTCACTCGACCGCGCGGCTCACGGGTGCCCTGTGACCCCAAAGCGGAGCTCGCAGCGG
CTGCCACCCGGCCCTGCCAGCCATGAGGCATGCGCCTTCCCTGGTCCTTTTCCTCCTGGTCGCC
CTTTGCGGGCGGGAATGAGCGAGAGCAGATCATGACCACCAATGTCTGGCTGAAACAGGAATGG
ACTGATTACCGCCTGACCTGGAACAGCTCCCGCTACGAGGGTGTGAACATCCTGAGGATCCCCG
CCAAGCGCATCTGGTTGCCTGACATCGTGCTTTACAACAATGCTGACGGGACCTATGAGGTGTC
TGTCTACACCAACTTGGTAGTCCGGTCCAACGGCAGGGTCCTGTGGCTGCCCCCTGCCATCTAC
AAGAGCGCCTGCAAGATTGAGGTGAAGTACTTTCCCTTCGACCAGCAGAACTGCACCCTCAAGT
TCCGCTCCTGGACCTATGACCACACAGAGATAGACATGGTCCTCATGACACCCACAGCCAGCAT
GGATGACTTTACTCCCAGTGGTGAGTGGGACATAGTGGCCCTCCCAGGGAGAAGGACAGTGAAC
CCACAGGACCCCAGCTATGTGGACGTGACTTACGACTTCATCATCAAGCGCAAGCCTCTGTTCT
ACACCATCAACCTCATCATCCCCTGCGTGCTCATCACCTCGCTGGCCATCCTCGTCTTCTACCT
GCCGTCCGACTGCGGCGAGAAGATGACGCTGTGCATCTCTGTGCTGCTGGCGCTCACAGTCTTC
CTGCTGCTCATCTCCAAGATCGTGCCACCCACCTCCCTCGATGTGCCTCTCATTGGCAAGTACC
TCATGTTCACCATGGTGCTGGTCACCTTCTCCATCGTCACCAGCGTCTGTGTGCTCAATGTGCA
CCACCGCTCACCCAGCACCCACACGATGGCACCCTGGGTCAAGCGCTGCTTCCTGCACAAGCTG
CCTACCTTCCTCTTCATGAAGCGCCCTGGCCCTGACAGCAGCCTGGCCAGAGCCTTCCCGCCCA
GCAAGTCACACGTGACCAAGCCCAAGGCCACCACCACCTCCACCAGCCCCTCCAAACTCTATGG
GAACTCCATGTACTTTGTGAACCCTGCCTCTGCAGCTCCCAAGTCTCCAGCCGGCTCCAGGGAT
TTCTGGCTGCGGTCCTCTGGGAGGTTCCGACAGGATGTGCAGGAGGCATTAGAAGGTGTCAGCT
TCATCCCCCAGCACATGAAGAATGACAATGAAGACCAGAGTGTCGTTGAGGACTGGAAGTACGT
GGCTATGGTGGTAGACCGGCTGTTCCTGTGGGTGTTCGTGTTTGTGTGCGTACTGGGCACTGTT
GGGCTCTTCCTACCGCCCCTCTTCCAGACCCACACAGCTTCCGAAGGGCCCTACGCTGCCCAGC
GTGACTGAGGGCCCCCTGGGTTGTGGGATGACAGGATGTGAGTGGCCGGGTGAGCAGTTTGCTG
CTTCCTTCTGGGTTGTGGCTGATGAGGCCCTAAATAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008013892	(Get FASTA)	NCBI Sequence Viewer
	XP_008013893	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000011104.1

RefSeq Acc Id:	XP_008013893 ⟸ XM_008015702
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9RR65 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_008013892 ⟸ XM_008015701
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RR65 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000011104 ⟸ ENSCSAT00000013092

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000014997	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000013092.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.58.390	UniProtKB/TrEMBL
	2.70.170.10	UniProtKB/TrEMBL
InterPro	Neur_chan_lig-bd	UniProtKB/TrEMBL
	Neur_chan_lig-bd_sf	UniProtKB/TrEMBL
	Neur_channel	UniProtKB/TrEMBL
	Neuro-gated_channel_TM_sf	UniProtKB/TrEMBL
	Neuro_actylchol_rec	UniProtKB/TrEMBL
	Neurotrans-gated_channel_TM	UniProtKB/TrEMBL
	Neurotransmitter_ion_chnl_CS	UniProtKB/TrEMBL
	Nicotinic_acetylcholine_rcpt	UniProtKB/TrEMBL
KEGG Report	csab:103245246	UniProtKB/TrEMBL
NCBI Gene	CHRNB4	ENTREZGENE
PANTHER	NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-4	UniProtKB/TrEMBL
	PTHR18945	UniProtKB/TrEMBL
Pfam	Neur_chan_LBD	UniProtKB/TrEMBL
	Neur_chan_memb	UniProtKB/TrEMBL
PRINTS	NICOTINICR	UniProtKB/TrEMBL
	NRIONCHANNEL	UniProtKB/TrEMBL
PROSITE	NEUROTR_ION_CHANNEL	UniProtKB/TrEMBL
Superfamily-SCOP	SSF63712	UniProtKB/TrEMBL
	SSF90112	UniProtKB/TrEMBL
UniProt	A0A0D9RR65	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations