LYPLA1 (lysophospholipase 1) - Rat Genome Database

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Gene: LYPLA1 (lysophospholipase 1) Chlorocebus sabaeus
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Symbol: LYPLA1
Name: lysophospholipase 1
RGD ID: 18492380
Description: ENCODES a protein that exhibits lipase activity (ortholog); lysophospholipase activity (ortholog); phospholipase activity (ortholog); INVOLVED IN fatty acid transport (ortholog); negative regulation of aggrephagy (ortholog); negative regulation of Golgi to plasma membrane protein transport (ortholog); PARTICIPATES IN glycerophospholipid metabolic pathway; ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acyl-protein thioesterase 1; lysophospholipase I
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1850,120,930 - 50,171,517 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603991,764,068 - 91,814,847 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LYPLA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1850,120,930 - 50,171,517 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603991,764,068 - 91,814,847 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LYPLA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38854,046,367 - 54,101,947 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl854,046,367 - 54,102,017 (-)EnsemblGRCh38hg38GRCh38
GRCh37854,958,927 - 55,014,507 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36855,121,491 - 55,177,130 (-)NCBINCBI36Build 36hg18NCBI36
Build 34855,121,490 - 55,177,130NCBI
Celera850,949,236 - 51,005,140 (-)NCBICelera
Cytogenetic Map8q11.23NCBI
HuRef850,427,322 - 50,482,732 (-)NCBIHuRef
CHM1_1855,010,550 - 55,065,879 (-)NCBICHM1_1
T2T-CHM13v2.0854,423,759 - 54,479,027 (-)NCBIT2T-CHM13v2.0
Lypla1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914,878,046 - 4,916,958 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14,878,011 - 4,918,633 (+)EnsemblGRCm39 Ensembl
GRCm3814,807,823 - 4,846,735 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14,807,788 - 4,848,410 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714,797,974 - 4,836,816 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614,797,974 - 4,836,816 (+)NCBIMGSCv36mm8
Celera14,819,711 - 4,858,108 (+)NCBICelera
Cytogenetic Map1A1NCBI
cM Map11.79NCBI
Lypla1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8519,477,408 - 19,506,568 (-)NCBIGRCr8
mRatBN7.2514,679,605 - 14,708,774 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl514,679,606 - 14,708,746 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx516,873,890 - 16,902,965 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0518,487,392 - 18,516,463 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0518,208,564 - 18,237,635 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0514,559,333 - 14,588,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl514,559,334 - 14,588,422 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0519,341,836 - 19,370,929 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4514,882,196 - 14,911,284 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1514,882,195 - 14,911,284 (-)NCBI
Celera514,050,814 - 14,079,913 (-)NCBICelera
Cytogenetic Map5q12NCBI
Lypla1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545413,356,851 - 13,385,110 (-)NCBIChiLan1.0ChiLan1.0
LYPLA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2769,685,881 - 69,740,846 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1845,410,670 - 45,465,681 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0850,474,238 - 50,529,167 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1847,850,592 - 47,905,377 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl847,850,592 - 47,905,367 (-)Ensemblpanpan1.1panPan2
LYPLA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1295,656,376 - 5,696,901 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl295,616,961 - 5,697,284 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha296,031,347 - 6,072,546 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0295,732,636 - 5,773,863 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl295,691,587 - 5,773,875 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1295,669,309 - 5,710,546 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0295,874,942 - 5,916,139 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0295,957,952 - 5,999,169 (-)NCBIUU_Cfam_GSD_1.0
Lypla1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530373,814,174 - 73,848,519 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936496936,763 - 971,710 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936496937,918 - 971,315 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LYPLA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl477,083,548 - 77,102,408 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1477,083,624 - 77,102,407 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2484,154,849 - 84,172,657 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Lypla1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247351,582,169 - 1,622,307 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: XM_008000648   ⟹   XP_007998839
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1850,120,930 - 50,171,517 (-)NCBI
Vero_WHO_p1.0NW_02366603991,764,068 - 91,814,845 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008000649   ⟹   XP_007998840
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1850,120,930 - 50,171,431 (-)NCBI
Vero_WHO_p1.0NW_02366603991,764,078 - 91,813,310 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008000652   ⟹   XP_007998843
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1850,120,930 - 50,171,517 (-)NCBI
Vero_WHO_p1.0NW_02366603991,764,118 - 91,814,845 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008000654   ⟹   XP_007998845
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1850,120,930 - 50,171,029 (-)NCBI
Vero_WHO_p1.0NW_02366603991,764,545 - 91,813,310 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038000501   ⟹   XP_037856429
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603991,764,548 - 91,814,847 (+)NCBI
RefSeq Acc Id: XP_007998843   ⟸   XM_008000652
- Peptide Label: isoform X3
- UniProtKB: A0A0D9R4Q4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007998839   ⟸   XM_008000648
- Peptide Label: isoform X1
- UniProtKB: A0A0D9SDU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007998840   ⟸   XM_008000649
- Peptide Label: isoform X2
- UniProtKB: A0A0D9SDU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007998845   ⟸   XM_008000654
- Peptide Label: isoform X3
- UniProtKB: A0A0D9R4Q4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037856429   ⟸   XM_038000501
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000007333 UniProtKB/TrEMBL
  ENSCSAG00000019536 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000005376.1 UniProtKB/TrEMBL
  ENSCSAT00000019626.1 UniProtKB/TrEMBL
Gene3D-CATH alpha/beta hydrolase UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  PLipase/COase/thioEstase UniProtKB/TrEMBL
NCBI Gene LYPLA1 ENTREZGENE
PANTHER ACYL-PROTEIN THIOESTERASE 1 UniProtKB/TrEMBL
  LYSOPHOSPHOLIPASE-RELATED UniProtKB/TrEMBL
Pfam Abhydrolase_2 UniProtKB/TrEMBL
Superfamily-SCOP alpha/beta-Hydrolases UniProtKB/TrEMBL
UniProt A0A0D9R4Q4 ENTREZGENE, UniProtKB/TrEMBL
  A0A0D9SDU6 ENTREZGENE, UniProtKB/TrEMBL