LOC103237562 (DNA topoisomerase I mitochondrial) - Rat Genome Database

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Gene: LOC103237562 (DNA topoisomerase I mitochondrial) Chlorocebus sabaeus
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Symbol: LOC103237562 (Ensembl: TOP1MT)
Name: DNA topoisomerase I mitochondrial
RGD ID: 18490947
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA topoisomerase activity (inferred); DNA topoisomerase type I (single strand cut, ATP-independent) activity (inferred); INVOLVED IN DNA replication (inferred); DNA topological change (inferred); FOUND IN chromosome (inferred); mitochondrial nucleoid (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA topoisomerase I, mitochondrial; TOP1MT; topoisomerase (DNA) I, mitochondrial
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18137,523,739 - 137,574,672 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8137,523,955 - 137,552,407 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236670188,188 - 24,004 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008001737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008001759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037996039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000007173   ⟹   ENSCSAP00000005360
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl8137,523,955 - 137,552,407 (-)Ensembl
RefSeq Acc Id: XM_037996039   ⟹   XP_037851967
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236670188,188 - 24,004 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037851967 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000005360.1
Ensembl Acc Id: ENSCSAP00000005360   ⟸   ENSCSAT00000007173
RefSeq Acc Id: XP_037851967   ⟸   XM_037996039


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000009107 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000007173.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.41 UniProtKB/TrEMBL
  1.10.132.10 UniProtKB/TrEMBL
  2.170.11.10 UniProtKB/TrEMBL
InterPro DNA_brk_join_enz UniProtKB/TrEMBL
  DNA_topo_DNA_db_N_dom1 UniProtKB/TrEMBL
  DNA_topo_DNA_db_N_dom2 UniProtKB/TrEMBL
  TopoI UniProtKB/TrEMBL
  TopoI_AS UniProtKB/TrEMBL
  TopoI_C_dom UniProtKB/TrEMBL
  TopoI_cat_a-hlx-sub_euk UniProtKB/TrEMBL
  TopoI_cat_a/b-sub_euk UniProtKB/TrEMBL
  TopoI_cat_euk UniProtKB/TrEMBL
  TopoI_DNA-bd_euk UniProtKB/TrEMBL
  TopoI_DNA-bd_euk_N_sf UniProtKB/TrEMBL
  TopoI_euk UniProtKB/TrEMBL
  Topoisomer_I_DNA-bd UniProtKB/TrEMBL
  Topoisomerase_IB UniProtKB/TrEMBL
NCBI Gene TOP1MT ENTREZGENE
PANTHER DNA TOPOISOMERASE I UniProtKB/TrEMBL
  DNA TOPOISOMERASE I, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam Topo_C_assoc UniProtKB/TrEMBL
  Topoisom_I UniProtKB/TrEMBL
  Topoisom_I_N UniProtKB/TrEMBL
PRINTS EUTPISMRASEI UniProtKB/TrEMBL
PROSITE TOPOISOMERASE_I_EUK UniProtKB/TrEMBL
SMART TOPEUc UniProtKB/TrEMBL
Superfamily-SCOP Eukaryotic DNA topoisomerase I, dispensable insert domain UniProtKB/TrEMBL
  SSF56349 UniProtKB/TrEMBL
  SSF56741 UniProtKB/TrEMBL
UniProt A0A0D9R9S1_CHLSB UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 LOC103237562  DNA topoisomerase I mitochondrial  TOP1MT  DNA topoisomerase I mitochondrial  Symbol and/or name change 5135510 APPROVED