TRMT6 (tRNA methyltransferase 6 non-catalytic subunit) - Rat Genome Database

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Gene: TRMT6 (tRNA methyltransferase 6 non-catalytic subunit) Chlorocebus sabaeus
Analyze
Symbol: TRMT6
Name: tRNA methyltransferase 6 non-catalytic subunit
RGD ID: 18487053
Description: INVOLVED IN obsolete mRNA methylation (inferred); tRNA methylation (inferred); tRNA processing (inferred); ASSOCIATED WITH genetic disease (ortholog); Huntington's disease-like 1 (ortholog); pantothenate kinase-associated neurodegeneration (ortholog); FOUND IN tRNA (m1A) methyltransferase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; tRNA methyltransferase 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1232,181,276 - 32,195,024 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl232,181,279 - 32,195,019 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607112,346,452 - 12,360,021 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TRMT6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1232,181,276 - 32,195,024 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl232,181,279 - 32,195,019 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607112,346,452 - 12,360,021 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TRMT6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38205,937,228 - 5,950,533 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl205,937,228 - 5,950,558 (-)EnsemblGRCh38hg38GRCh38
GRCh37205,917,874 - 5,931,179 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36205,866,486 - 5,879,173 (-)NCBINCBI36Build 36hg18NCBI36
Celera205,990,095 - 6,002,785 (-)NCBICelera
Cytogenetic Map20p12.3NCBI
HuRef205,875,029 - 5,887,738 (-)NCBIHuRef
CHM1_1205,918,869 - 5,931,593 (-)NCBICHM1_1
T2T-CHM13v2.0205,977,563 - 5,990,868 (-)NCBIT2T-CHM13v2.0
Trmt6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392132,646,127 - 132,658,127 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2132,646,127 - 132,657,975 (-)EnsemblGRCm39 Ensembl
GRCm382132,804,207 - 132,816,054 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2132,804,207 - 132,816,055 (-)EnsemblGRCm38mm10GRCm38
MGSCv372132,629,951 - 132,641,790 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362132,495,656 - 132,507,496 (-)NCBIMGSCv36mm8
Celera2134,031,674 - 134,043,498 (-)NCBICelera
Cytogenetic Map2F2NCBI
cM Map264.74NCBI
Trmt6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83140,527,785 - 140,539,520 (-)NCBIGRCr8
mRatBN7.23120,074,899 - 120,086,639 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3120,074,911 - 120,086,559 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3123,969,956 - 123,981,674 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03132,573,585 - 132,585,306 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03130,226,090 - 130,237,808 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03125,458,692 - 125,470,413 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3125,458,692 - 125,470,413 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03131,942,467 - 131,954,194 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43120,602,570 - 120,614,291 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13120,509,438 - 120,519,743 (-)NCBI
Celera3118,860,870 - 118,872,591 (-)NCBICelera
Cytogenetic Map3q36NCBI
Trmt6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541516,330,482 - 16,344,973 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541516,333,766 - 16,390,112 (-)NCBIChiLan1.0ChiLan1.0
TRMT6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2216,859,872 - 6,872,629 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1206,856,698 - 6,869,445 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0205,932,217 - 5,944,930 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1205,715,016 - 5,727,726 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl205,715,015 - 5,727,726 (-)Ensemblpanpan1.1panPan2
TRMT6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12415,836,359 - 15,905,147 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2415,893,335 - 15,903,889 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2415,658,478 - 15,728,233 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02416,238,910 - 16,308,685 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2416,296,017 - 16,315,027 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12415,845,681 - 15,915,204 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02415,953,824 - 16,023,561 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02416,285,565 - 16,355,086 (+)NCBIUU_Cfam_GSD_1.0
Trmt6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640164,677,074 - 164,689,921 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648513,108,588 - 13,119,939 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648513,108,450 - 13,121,276 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRMT6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1714,777,683 - 14,965,130 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11714,777,683 - 14,790,318 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21715,885,122 - 15,896,868 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Trmt6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247416,775,944 - 6,788,161 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247416,774,767 - 6,787,461 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 33
Low 20 27
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000011551   ⟹   ENSCSAP00000009618
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl232,181,279 - 32,195,019 (+)Ensembl
RefSeq Acc Id: XM_008018698   ⟹   XP_008016889
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1232,181,276 - 32,195,024 (+)NCBI
Vero_WHO_p1.0NW_02366607112,346,452 - 12,360,021 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037990693   ⟹   XP_037846621
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607112,346,452 - 12,359,882 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008016889 (Get FASTA)   NCBI Sequence Viewer  
  XP_037846621 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000009618.1
Reference Protein Sequences
RefSeq Acc Id: XP_008016889   ⟸   XM_008018698
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RLX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000009618   ⟸   ENSCSAT00000011551
RefSeq Acc Id: XP_037846621   ⟸   XM_037990693
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013461 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011551.1 UniProtKB/TrEMBL
InterPro TRM6 UniProtKB/TrEMBL
KEGG Report csab:103246794 UniProtKB/TrEMBL
NCBI Gene TRMT6 ENTREZGENE
PANTHER PTHR12945 UniProtKB/TrEMBL
  TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6 UniProtKB/TrEMBL
Pfam Gcd10p UniProtKB/TrEMBL
PIRSF tRNA_m1A_mtfrase UniProtKB/TrEMBL
UniProt A0A0D9RLX9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-05-18 TRMT6  tRNA methyltransferase 6 non-catalytic subunit  TRMT6  tRNA methyltransferase 6  Symbol and/or name change 5135510 APPROVED