IMPA1 (inositol monophosphatase 1) - Rat Genome Database

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Gene: IMPA1 (inositol monophosphatase 1) Chlorocebus sabaeus
Analyze
Symbol: IMPA1
Name: inositol monophosphatase 1
RGD ID: 18485371
Description: ENCODES a protein that exhibits inositol monophosphate 1-phosphatase activity (ortholog); INVOLVED IN phosphatidylinositol biosynthetic process (ortholog); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; ASSOCIATED WITH autosomal recessive intellectual developmental disorder 59 (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN axon (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1877,073,577 - 77,100,418 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl877,074,805 - 77,100,862 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603964,094,905 - 64,121,746 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (ISO)
cytoplasm  (IEA)
neuronal cell body  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
IMPA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1877,073,577 - 77,100,418 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl877,074,805 - 77,100,862 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603964,094,905 - 64,121,746 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
IMPA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38881,656,914 - 81,686,325 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl881,656,914 - 81,686,331 (-)EnsemblGRCh38hg38GRCh38
GRCh37882,569,149 - 82,598,560 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36882,732,751 - 82,761,115 (-)NCBINCBI36Build 36hg18NCBI36
Build 34882,732,750 - 82,761,115NCBI
Celera878,574,122 - 78,603,090 (-)NCBICelera
Cytogenetic Map8q21.13NCBI
HuRef878,058,964 - 78,088,484 (-)NCBIHuRef
CHM1_1882,620,772 - 82,650,210 (-)NCBICHM1_1
T2T-CHM13v2.0882,088,505 - 82,118,041 (-)NCBIT2T-CHM13v2.0
Impa1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39310,377,016 - 10,396,499 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl310,377,016 - 10,396,499 (-)EnsemblGRCm39 Ensembl
GRCm38310,311,956 - 10,331,439 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl310,311,956 - 10,331,439 (-)EnsemblGRCm38mm10GRCm38
MGSCv37310,313,540 - 10,331,439 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36310,296,072 - 10,313,904 (-)NCBIMGSCv36mm8
Celera310,347,693 - 10,365,549 (-)NCBICelera
Cytogenetic Map3A1NCBI
cM Map32.61NCBI
Impa1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8293,370,200 - 93,391,474 (+)NCBIGRCr8
mRatBN7.2291,462,781 - 91,484,057 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl291,462,799 - 91,484,313 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx297,953,286 - 97,974,472 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0296,074,274 - 96,095,454 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0291,131,126 - 91,152,304 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0293,675,203 - 93,696,355 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl293,675,203 - 93,696,232 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02113,430,723 - 113,453,209 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4293,415,958 - 93,438,247 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1293,360,919 - 93,383,209 (+)NCBI
Celera287,065,842 - 87,086,646 (+)NCBICelera
Cytogenetic Map2q23NCBI
Impa1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541712,504 - 40,902 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541714,114 - 40,128 (-)NCBIChiLan1.0ChiLan1.0
IMPA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2797,392,378 - 97,423,805 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1873,019,820 - 73,053,140 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0878,177,200 - 78,209,901 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1879,800,265 - 79,829,713 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl879,800,257 - 79,829,935 (-)Ensemblpanpan1.1panPan2
IMPA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12928,772,044 - 28,799,170 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2928,771,853 - 28,799,077 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2929,050,877 - 29,078,089 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02928,903,802 - 28,931,360 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2928,902,020 - 28,931,365 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12928,973,370 - 29,000,580 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02928,987,403 - 29,014,731 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02929,344,086 - 29,371,303 (-)NCBIUU_Cfam_GSD_1.0
Impa1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530350,407,891 - 50,427,696 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366562,598,413 - 2,618,396 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366562,598,454 - 2,616,643 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IMPA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl454,935,860 - 54,984,238 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1454,935,838 - 54,968,672 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Impa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247449,817,004 - 9,839,760 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247449,817,723 - 9,839,186 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 20 2 58
Low 16 18 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008000975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000011330   ⟹   ENSCSAP00000009409
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl877,074,805 - 77,100,862 (-)Ensembl
RefSeq Acc Id: XM_008000975   ⟹   XP_007999166
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1877,073,577 - 77,100,418 (-)NCBI
Vero_WHO_p1.0NW_02366603964,094,905 - 64,121,746 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007999166 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000009409
  ENSCSAP00000009409.1
Reference Protein Sequences
RefSeq Acc Id: XP_007999166   ⟸   XM_008000975
RefSeq Acc Id: ENSCSAP00000009409   ⟸   ENSCSAT00000011330


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013240 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011330.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.190.80 UniProtKB/TrEMBL
  Fructose-1,6-Bisphosphatase, subunit A, domain 1 UniProtKB/TrEMBL
InterPro IMPase UniProtKB/TrEMBL
  Inositol_monoP_metal-BS UniProtKB/TrEMBL
  Inositol_monoPase_Li-sen UniProtKB/TrEMBL
  Inositol_monophosphatase-like UniProtKB/TrEMBL
  Inositol_monophosphatase_CS UniProtKB/TrEMBL
NCBI Gene IMPA1 ENTREZGENE
PANTHER INOSITOL MONOPHOSPHATASE UniProtKB/TrEMBL
  INOSITOL MONOPHOSPHATASE 1 UniProtKB/TrEMBL
Pfam Inositol_P UniProtKB/TrEMBL
PRINTS IMPHPHTASES UniProtKB/TrEMBL
  LIIMPHPHTASE UniProtKB/TrEMBL
PROSITE IMP_1 UniProtKB/TrEMBL
  IMP_2 UniProtKB/TrEMBL
Superfamily-SCOP Carbohydrate phosphatase UniProtKB/TrEMBL
UniProt A0A0D9RLC0_CHLSB UniProtKB/TrEMBL