TASP1 (taspase 1) - Rat Genome Database

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Gene: TASP1 (taspase 1) Chlorocebus sabaeus
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Symbol: TASP1
Name: taspase 1
RGD ID: 18484484
Description: ENCODES a protein that exhibits asparaginase activity (inferred); beta-aspartyl-peptidase activity (inferred); identical protein binding (inferred); INVOLVED IN positive regulation of DNA-templated transcription (inferred); protein maturation (inferred); proteolysis (inferred); ASSOCIATED WITH Developmental Disabilities (ortholog); genetic disease (ortholog); Multiple Abnormalities (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: threonine aspartase 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1242,284,264 - 42,529,551 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl242,283,687 - 42,529,488 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660542,556,617 - 2,806,243 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TASP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1242,284,264 - 42,529,551 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl242,283,687 - 42,529,488 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660542,556,617 - 2,806,243 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TASP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382013,104,772 - 13,638,932 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2013,389,392 - 13,638,932 (-)EnsemblGRCh38hg38GRCh38
GRCh372013,370,041 - 13,619,579 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362013,318,036 - 13,567,583 (-)NCBINCBI36Build 36hg18NCBI36
Build 342013,318,038 - 13,558,799NCBI
Celera2013,440,107 - 13,689,648 (-)NCBICelera
Cytogenetic Map20p12.1NCBI
HuRef2013,324,503 - 13,574,057 (-)NCBIHuRef
CHM1_12013,370,132 - 13,618,116 (-)NCBICHM1_1
T2T-CHM13v2.02013,148,109 - 13,682,349 (-)NCBIT2T-CHM13v2.0
Tasp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392139,675,399 - 139,908,767 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2139,675,400 - 139,908,725 (-)EnsemblGRCm39 Ensembl
GRCm382139,833,479 - 140,066,847 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2139,833,480 - 140,066,805 (-)EnsemblGRCm38mm10GRCm38
MGSCv372139,659,216 - 139,892,521 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362139,525,027 - 139,758,201 (-)NCBIMGSCv36mm8
Celera2141,009,953 - 141,252,432 (-)NCBICelera
Cytogenetic Map2F3NCBI
cM Map269.2NCBI
Tasp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83147,630,092 - 147,861,710 (-)NCBIGRCr8
mRatBN7.23127,176,416 - 127,408,039 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3127,176,692 - 127,399,600 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3131,032,864 - 131,255,561 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03139,616,956 - 139,839,650 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03137,320,092 - 137,542,788 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03132,888,785 - 133,131,213 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3132,888,772 - 133,131,192 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03139,347,611 - 139,588,372 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43128,002,479 - 128,228,127 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13127,907,732 - 128,133,709 (-)NCBI
Celera3125,825,868 - 126,047,420 (-)NCBICelera
Cytogenetic Map3q36NCBI
Tasp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541522,855,822 - 23,091,732 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541522,856,382 - 23,091,732 (-)NCBIChiLan1.0ChiLan1.0
TASP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22114,277,972 - 14,527,701 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12014,274,800 - 14,524,549 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02013,350,135 - 13,599,861 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12013,335,443 - 13,584,376 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2013,335,443 - 13,584,378 (-)Ensemblpanpan1.1panPan2
TASP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1249,001,175 - 9,314,212 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl249,001,246 - 9,324,695 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha248,813,171 - 9,126,408 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0249,414,188 - 9,728,318 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl249,414,289 - 9,738,817 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1249,013,582 - 9,338,011 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0249,109,971 - 9,423,426 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0249,458,664 - 9,772,420 (+)NCBIUU_Cfam_GSD_1.0
Tasp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640157,732,386 - 158,028,997 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364856,163,809 - 6,460,360 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364856,163,809 - 6,460,361 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TASP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1722,083,819 - 22,357,476 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11721,963,369 - 22,358,444 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21724,534,792 - 24,918,068 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Tasp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474114,352,360 - 14,633,373 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474114,341,076 - 14,633,441 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 12 31
Low 24 20 29
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000009883   ⟹   ENSCSAP00000007989
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl242,283,687 - 42,529,488 (-)Ensembl
RefSeq Acc Id: XM_007960419   ⟹   XP_007958610
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1242,284,264 - 42,529,551 (-)NCBI
Vero_WHO_p1.0NW_0236660542,556,617 - 2,806,243 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007960427   ⟹   XP_007958618
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1242,284,266 - 42,529,339 (-)NCBI
Vero_WHO_p1.0NW_0236660542,556,617 - 2,806,132 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007960431   ⟹   XP_007958622
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1242,284,266 - 42,529,122 (-)NCBI
Vero_WHO_p1.0NW_0236660542,556,617 - 2,806,132 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037984750   ⟹   XP_037840678
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660542,556,617 - 2,806,211 (-)NCBI
RefSeq Acc Id: XM_037984751   ⟹   XP_037840679
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660542,556,617 - 2,763,105 (-)NCBI
RefSeq Acc Id: XR_005235672
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660542,556,617 - 2,806,243 (-)NCBI
RefSeq Acc Id: XR_005235673
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660542,556,617 - 2,806,243 (-)NCBI
RefSeq Acc Id: XP_007958610   ⟸   XM_007960419
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RHA0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007958618   ⟸   XM_007960427
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RHA0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007958622   ⟸   XM_007960431
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RHA0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000007989   ⟸   ENSCSAT00000009883
RefSeq Acc Id: XP_037840678   ⟸   XM_037984750
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037840679   ⟸   XM_037984751
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011790 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009883.1 UniProtKB/TrEMBL
Gene3D-CATH (Glycosyl)asparaginase UniProtKB/TrEMBL
InterPro Ntn_hydrolases_N UniProtKB/TrEMBL
  Peptidase_T2 UniProtKB/TrEMBL
  Taspase1 UniProtKB/TrEMBL
KEGG Report csab:103214434 UniProtKB/TrEMBL
NCBI Gene TASP1 ENTREZGENE
PANTHER PTHR10188 UniProtKB/TrEMBL
  THREONINE ASPARTASE 1 UniProtKB/TrEMBL
Pfam Asparaginase_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF56235 UniProtKB/TrEMBL
UniProt A0A0D9RHA0 ENTREZGENE, UniProtKB/TrEMBL