CMTM2 (CKLF like MARVEL transmembrane domain containing 2)

Gene: CMTM2 (CKLF like MARVEL transmembrane domain containing 2) Chlorocebus sabaeus

Analyze

Symbol:

CMTM2

Name:

CKLF like MARVEL transmembrane domain containing 2

RGD ID:

18482011

Description:

ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); cataract 5 multiple types (ortholog); COVID-19 (ortholog); FOUND IN membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

CKLF-like MARVEL transmembrane domain-containing protein 2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	52,272,567 - 52,287,025 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	52,272,717 - 52,286,869 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	23,627,639 - 23,642,329 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant dyskeratosis congenita 6 (ISO)

cataract 5 multiple types (ISO)

COVID-19 (ISO)

genetic disease (ISO)

juvenile rheumatoid arthritis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

membrane (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

CMTM2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	52,272,567 - 52,287,025 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	52,272,717 - 52,286,869 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	23,627,639 - 23,642,329 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

CMTM2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	66,579,463 - 66,588,275 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	66,579,448 - 66,588,275 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	66,613,366 - 66,622,178 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	65,170,852 - 65,179,679 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	65,170,851 - 65,179,676	NCBI
Celera	16	51,119,925 - 51,128,752 (+)	NCBI		Celera
Cytogenetic Map	16	q21	NCBI
HuRef	16	52,489,275 - 52,498,102 (+)	NCBI		HuRef
CHM1_1	16	68,020,529 - 68,029,356 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	72,373,758 - 72,382,570 (+)	NCBI		T2T-CHM13v2.0

Cmtm2a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	105,007,674 - 105,019,813 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	105,007,674 - 105,019,813 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	104,281,042 - 104,293,181 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	104,281,042 - 104,293,181 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	106,804,942 - 106,817,081 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	107,170,171 - 107,182,303 (-)	NCBI		MGSCv36	mm8
Celera	8	108,512,498 - 108,524,606 (-)	NCBI		Celera
Cytogenetic Map	8	D3	NCBI
cM Map	8	53.04	NCBI

Cmtm2a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	678,154 - 685,274 (+)	NCBI		GRCr8
mRatBN7.2	19	671,719 - 678,839 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	671,719 - 678,837 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	667,469 - 674,643 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	1,434,271 - 1,441,445 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	709,482 - 716,657 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	880,024 - 887,144 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	880,024 - 887,144 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	878,307 - 885,427 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	629,381 - 636,501 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	629,380 - 636,501 (+)	NCBI
Celera	19	667,618 - 674,738 (+)	NCBI		Celera
Cytogenetic Map	19	p14	NCBI

Cmtm2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955433	23,140,178 - 23,149,252 (+)	NCBI	ChiLan1.0	ChiLan1.0

CMTM2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	76,082,023 - 76,097,886 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	81,994,432 - 82,008,654 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	46,897,655 - 46,906,760 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	65,999,059 - 66,007,895 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	65,999,285 - 66,007,739 (+)	Ensembl	panpan1.1		panPan2

CMTM2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	82,679,457 - 82,696,686 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	82,679,473 - 82,697,153 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	82,667,938 - 82,685,168 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	83,116,259 - 83,133,457 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	83,116,275 - 83,133,931 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	82,939,271 - 82,956,499 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	82,632,574 - 82,649,761 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	83,264,787 - 83,282,017 (-)	NCBI		UU_Cfam_GSD_1.0

Cmtm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	42,667,764 - 42,672,710 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936475	16,916,568 - 16,921,196 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CMTM2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	27,282,070 - 27,295,522 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	27,281,809 - 27,295,429 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium
Low	20	16	60
Below cutoff	15	3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007993579	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038008384	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000002682 ⟹ ENSCSAP00000000979

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	5	52,272,717 - 52,286,869 (+)	Ensembl

RefSeq Acc Id:

XM_007993579 ⟹ XP_007991770

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	5	52,272,567 - 52,287,025 (+)	NCBI
Vero_WHO_p1.0	NW_023666047	23,627,639 - 23,642,329 (-)	NCBI

Sequence:

show sequence

GCGTGGGAGTTGGCATTCGGTGGTCCTGGCAGTTAGCTGAGCGCGCCCTCTGAGCCGCTCGGTT
GACACCAGGCTCTCTAGTAGGCCTGGCCTACCCAGAAACAGCAGGAGAGAGAAGAAACAGGCCA
GCTGTGAGAAGTCAAGGACACCGAGTCAATCATGGCGGCAAAAGGGGCCAAGACAGAGCCAGCT
CCACCTCCAGCCGGGGCCAAACCCCAGGAGGACAAGAAGGACGATAAGGAGCCATTGGACAAAC
CTCAAAAGTTGGTGCAGCCCAAGCACGAAGTGGGCACGAGGAAGGGGTGTCGCCGCTACCGGTG
GGAATTAAAAGACAGCAATAGAGAGTTCTGGCTCTTGGGGCACGCTGAGGTCAAGATTCTGAGT
TTGGGCTGCCTAATAGCGGCAATGATACTGTTGTCCTCACTCAGCGTGCACCCCATCTTGACGC
TTATCATCACCATGGAGATATCCATCTTCAGTTTCTTCATCATACTGTACAGCTTTGCCATTCA
TAGATACATACCCTTCATCCTGTGGCCCATTTCTGACCTGTTCAACGACCTGTTTGCCTGTGCG
TTCCTGGTGGGAGCCGTGGTCTTTGCTGCGAGAAGTCGGCGATCCATGCATCTCCACTACTTAC
TTGCTGTGATCCTTATTGGTGTGGCTGGAGTTTTTGCTTTGATCGATATGTGTCTTCAAAGAAA
CAACTTCAGAGGCAAGAGGGCCAAAAAGCATATGCTGATTTCTCCTCCAGGCAAAGAAAAAGAA
CCCCAGCAGGGCAAGGGACCAGAACCCGCCAAGCCACCAGAGCCAGCAAAGGGAAAGAAATGAC
TTGGAGGAGGCTCCTACTGTCTGAAACGGCAGTGTATTTTACAGCAATACATTTCTACTCTCTT
CCTTGTCTTCTTTCTAGAATGGTTTTCTTTTCCATTTTCATTACCACCTTTGCTTGGAAAAGAA
TGGATTAATGGATTCTAAAAGCCTAAA

hide sequence

RefSeq Acc Id:

XM_038008384 ⟹ XP_037864312

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666047	23,627,639 - 23,642,329 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_007991770	(Get FASTA)	NCBI Sequence Viewer
	XP_037864312	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000000979.1

RefSeq Acc Id:	XP_007991770 ⟸ XM_007993579
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9QX90 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000000979 ⟸ ENSCSAT00000002682

RefSeq Acc Id:	XP_037864312 ⟸ XM_038008384
- Peptide Label:	isoform X2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000004650	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000002682.1	UniProtKB/TrEMBL
InterPro	Marvel	UniProtKB/TrEMBL
NCBI Gene	CMTM2	ENTREZGENE
PANTHER	CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2	UniProtKB/TrEMBL
	MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN	UniProtKB/TrEMBL
Pfam	MARVEL	UniProtKB/TrEMBL
PROSITE	MARVEL	UniProtKB/TrEMBL
UniProt	A0A0D9QX90	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD